BR0111497A - Processo de obtenção de uma população celular, população de células e utilização da mesma - Google Patents

Processo de obtenção de uma população celular, população de células e utilização da mesma

Info

Publication number
BR0111497A
BR0111497A BR0111497-2A BR0111497A BR0111497A BR 0111497 A BR0111497 A BR 0111497A BR 0111497 A BR0111497 A BR 0111497A BR 0111497 A BR0111497 A BR 0111497A
Authority
BR
Brazil
Prior art keywords
cell
cell population
obtaining
preparation
muscle tissue
Prior art date
Application number
BR0111497-2A
Other languages
English (en)
Inventor
Jean-Thomas Vilquin
Jean-Pierre Marolleau
Jacques Tremblay
Isabelle Robert
Brigitte Ternaux
Original Assignee
Assist Publ Hopitaux De Paris
Inst Nat Sante Rech Med
Ass Fr Contre Les Myopathies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Assist Publ Hopitaux De Paris, Inst Nat Sante Rech Med, Ass Fr Contre Les Myopathies filed Critical Assist Publ Hopitaux De Paris
Publication of BR0111497A publication Critical patent/BR0111497A/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Adornments (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"PROCESSO DE OBTENçãO DE UMA POPULAçãO CELULAR, POPULAçãO DE CéLULAS E UTILIZAçãO DA MESMA". A invenção trata de um processo de obtenção de populações celulares provenientes do tecido muscular e sua utilização na preparação de produtos de terapia celular. Ela consiste, particularmente, em colocar em cultura as células previamente retiradas por biópsia dos tecidos musculares esqueléticos, em identificar os diferentes tipos celulares presentes nos diferentes estados da cultura, em escolher o estado de cultura em função da população celular procurada e em coletar as células no estado de cultura escolhidas para a preparação de um produto de terapia celular. Ela refere-se igualmente às populações celulares provenientes do tecido muscular obtidas pela realização do processo cujo tipo celular dominante é CD34+, CD15+ ou CD56+ ou HLA Classe 1+, ou compreende um tipo celular duplamente negativo CD56-/CD15-, ou pode compreender tipos celulares mais minoritários CD10+ , Stro-1+ e CD117+.
BR0111497-2A 2000-06-07 2001-06-07 Processo de obtenção de uma população celular, população de células e utilização da mesma BR0111497A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0007304A FR2810045B1 (fr) 2000-06-07 2000-06-07 Procede d'obtention de population cellulaires caracterisees d'origine musculaire et utilisations
PCT/FR2001/001768 WO2001094555A1 (fr) 2000-06-07 2001-06-07 Procede d'obtention de populations cellulaires caracterisees d'origine musculaire et utilisations

Publications (1)

Publication Number Publication Date
BR0111497A true BR0111497A (pt) 2004-04-06

Family

ID=8851058

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0111497-2A BR0111497A (pt) 2000-06-07 2001-06-07 Processo de obtenção de uma população celular, população de células e utilização da mesma

Country Status (14)

Country Link
US (3) US20040043008A1 (pt)
EP (1) EP1292671B9 (pt)
JP (1) JP2003535586A (pt)
AT (1) ATE449163T1 (pt)
AU (2) AU6612701A (pt)
BR (1) BR0111497A (pt)
CA (1) CA2411762A1 (pt)
CY (1) CY1109745T1 (pt)
DE (1) DE60140536D1 (pt)
DK (1) DK1292671T3 (pt)
ES (1) ES2335747T3 (pt)
FR (1) FR2810045B1 (pt)
PT (1) PT1292671E (pt)
WO (1) WO2001094555A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE365045T1 (de) * 2000-04-14 2007-07-15 Univ Pittsburgh Vermehrung des weich- sowie des knochengewebes anhand von aus muskeln stammenden vorläuferzellen,sowie damit verbundene zusammensetzungen und behandlungsformen
FR2810045B1 (fr) * 2000-06-07 2004-09-03 Assist Publ Hopitaux De Paris Procede d'obtention de population cellulaires caracterisees d'origine musculaire et utilisations
JP2005532090A (ja) * 2002-05-10 2005-10-27 イソラゲン テクノロジーズ，インコーポレーテッド 自己線維芽細胞を用いた治療
CN103230415B (zh) * 2003-04-25 2016-05-04 匹兹堡大学联邦制高等教育 用于促进和增强神经修复和再生的肌肉来源的细胞（mdc）
US20070202592A1 (en) * 2004-07-08 2007-08-30 Yasuo Kitagawa Pluripotent Cells Distributed Ubiquitously In Animal Tissue, Which Proliferate Selectively In Lower-Serum Culture
FR2890977A1 (fr) * 2005-09-19 2007-03-23 Assist Publ Hopitaux De Paris Procede d'obtention de cellules musculaires lisses humaines et leurs applications
FR2909559B1 (fr) * 2006-12-06 2012-09-07 Inst Vaisseaux Et Du Sang Preparations cellulaires pour une utilisation comme agent stimulant la revascularisation
ATE554160T1 (de) * 2007-05-29 2012-05-15 Univ Pittsburgh Knochenaufbau anhand von vorläuferzusammensetzungen aus muskeln und behandlungen damit
EP2206774A1 (en) 2008-12-23 2010-07-14 Genzyme Corporation Muscle-derived cells having differentiation capacities
MX338100B (es) * 2009-07-09 2016-04-01 Janssen Biotech Inc Celulas derivadas de tejido cardiaco.
FR3074018B1 (fr) 2017-11-27 2020-09-11 Lab Francais Du Fractionnement Procede de cryoconservation de cellules a visee therapeutique
FR3088541B1 (fr) 2018-11-15 2021-11-05 Lab Francais Du Fractionnement Procede de conservation de cellules a visee therapeutique
EP3976069A4 (en) 2019-05-31 2023-07-19 Figene, LLC FIBROBLAST THERAPY FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY
EP4026587A4 (en) * 2019-09-30 2022-11-16 TERUMO Kabushiki Kaisha METHOD OF INCREASING THE PERCENTAGE OF CD56+ CELLS
KR20240085728A (ko) * 2022-12-08 2024-06-17 주식회사 팡세 근육줄기세포의 분화능 예측을 위한 cd56의 용도

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143842A (en) * 1988-11-01 1992-09-01 The University Of Colorado Foundation, Inc. Media for normal human muscle satellite cells
US5538722A (en) * 1989-06-13 1996-07-23 Stanford University Isolation, growth, differentiation and genetic engineering of human muscle cells
US5574205A (en) * 1989-07-25 1996-11-12 Cell Genesys Homologous recombination for universal donor cells and chimeric mammalian hosts
ATE163971T1 (de) * 1989-08-03 1998-03-15 Univ California Verfahren zur isolierung von fetalen zytotrophoblastzellen
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5196315A (en) * 1990-05-01 1993-03-23 The Johns Hopkins University Human neuronal cell line
AU2593192A (en) * 1992-09-14 1994-04-12 Oystein Fodstad Detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations
EP0714510B1 (en) * 1993-08-27 2002-06-19 Dana Farber Cancer Institute Natural killer cell-specific antigen and antibodies that identify the same
US6110459A (en) * 1997-05-28 2000-08-29 Mickle; Donald A. G. Transplants for myocardial scars and methods and cellular preparations
JP2002507407A (ja) * 1998-03-23 2002-03-12 ザイモジェネティクス，インコーポレイティド 心臓由来幹細胞
WO1999056785A2 (en) * 1998-05-01 1999-11-11 University Of Pittsburgh Cell mediated gene delivery using muscle derived cells for treating muscle-and bone-related injury or dysfunction
US7368420B1 (en) * 1998-10-02 2008-05-06 Caritas St. Elizabeth's Medical Center Of Boston, Inc. Akt compositions for enhancing survival of cells
WO2001007568A2 (en) * 1999-07-23 2001-02-01 Diacrin, Inc. Muscle cells and their use in cardiac repair
US20030113301A1 (en) * 1999-07-23 2003-06-19 Albert Edge Muscle cells and their use in cardiac repair
FR2810045B1 (fr) * 2000-06-07 2004-09-03 Assist Publ Hopitaux De Paris Procede d'obtention de population cellulaires caracterisees d'origine musculaire et utilisations

Also Published As

Publication number Publication date
EP1292671B9 (fr) 2010-05-19
FR2810045A1 (fr) 2001-12-14
EP1292671A1 (fr) 2003-03-19
AU2001266127B2 (en) 2007-01-04
US20060088508A1 (en) 2006-04-27
DE60140536D1 (de) 2009-12-31
CA2411762A1 (fr) 2001-12-13
ES2335747T3 (es) 2010-04-05
WO2001094555A1 (fr) 2001-12-13
US20040043008A1 (en) 2004-03-04
US20110014159A1 (en) 2011-01-20
FR2810045B1 (fr) 2004-09-03
AU6612701A (en) 2001-12-17
DK1292671T3 (da) 2010-03-15
JP2003535586A (ja) 2003-12-02
ATE449163T1 (de) 2009-12-15
EP1292671B1 (fr) 2009-11-18
CY1109745T1 (el) 2014-09-10
PT1292671E (pt) 2010-02-05

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
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B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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Ipc: C12N 5/077 (2010.01), A61K 35/12 (2015.01), A61K 4