BR0012386A - (oxatiepino-[6,5-b]-dihidropiridinas e composições e processos relacionados - Google Patents
(oxatiepino-[6,5-b]-dihidropiridinas e composições e processos relacionadosInfo
- Publication number
- BR0012386A BR0012386A BR0012386-2A BR0012386A BR0012386A BR 0012386 A BR0012386 A BR 0012386A BR 0012386 A BR0012386 A BR 0012386A BR 0012386 A BR0012386 A BR 0012386A
- Authority
- BR
- Brazil
- Prior art keywords
- dihydropyridines
- processes
- disorders
- oxatiepino
- related compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
"OXATIEPINO-[ 6,5-b ]-DIHIDROPIRIDINAS E COMPOSIçõES E PROCESSOS RELACIONADOS". Esta invenção proporciona novas oxatiepino-[ 6,5-b ]-dihidropiridinas. Esses compostos são úteis como antagonistas de canais de cálcio com atividade cardiovascular, antiasmática e antibroncoconstrição. Assim, essa invenção também proporciona composições farmacêuticas, assim como processos, para prevenção e tratamento de distúrbios tais como hipersensibilidade, alergia, asma, broncoespasmo, dismenorréia, espasmo esofágico, glaucoma, parto prematuro, distúrbios do trato urinário, distúrbios da motilidade gastrointestinal e distúrbios cardiovasculares.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14335499P | 1999-07-12 | 1999-07-12 | |
PCT/US2000/017310 WO2001004124A1 (en) | 1999-07-12 | 2000-06-23 | OXATHIEPINO[6,5-b]DIHYDROPYRIDINES, AND RELATED COMPOSITIONS AND METHODS |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0012386A true BR0012386A (pt) | 2002-05-28 |
Family
ID=22503704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0012386-2A BR0012386A (pt) | 1999-07-12 | 2000-06-23 | (oxatiepino-[6,5-b]-dihidropiridinas e composições e processos relacionados |
Country Status (22)
Country | Link |
---|---|
US (1) | US6476022B1 (pt) |
EP (1) | EP1200446B1 (pt) |
JP (1) | JP2003504373A (pt) |
KR (1) | KR20020012308A (pt) |
CN (1) | CN1188416C (pt) |
AR (1) | AR030396A1 (pt) |
AT (1) | ATE302206T1 (pt) |
AU (1) | AU779498B2 (pt) |
BR (1) | BR0012386A (pt) |
CA (1) | CA2379199A1 (pt) |
CZ (1) | CZ2002126A3 (pt) |
DE (1) | DE60022056T2 (pt) |
DK (1) | DK1200446T3 (pt) |
ES (1) | ES2246248T3 (pt) |
HK (1) | HK1045506B (pt) |
HU (1) | HUP0202265A3 (pt) |
IL (2) | IL147540A0 (pt) |
MX (1) | MXPA02000436A (pt) |
PL (1) | PL352760A1 (pt) |
RU (1) | RU2257388C2 (pt) |
TW (1) | TWI256394B (pt) |
WO (1) | WO2001004124A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100870527B1 (ko) * | 2003-03-28 | 2008-11-26 | 닛산 가가쿠 고교 가부시키 가이샤 | T형 칼슘 채널 저해제 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA429975A (en) | 1945-09-11 | F. D'alelio Gaetano | Triazine derivative | |
US4285955A (en) | 1978-10-31 | 1981-08-25 | Bayer Aktiengesellschaft | 1,4-Dihydropyridinecarboxylic acids |
US4483985A (en) | 1978-10-31 | 1984-11-20 | Bayer Aktiengesellschaft | Production of 1,4-dihydropyridinecarboxylic acids |
NZ201395A (en) | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
JPS58201764A (ja) | 1982-05-17 | 1983-11-24 | Maruko Seiyaku Kk | ジヒドロピリジン誘導体 |
JPS6139760A (ja) | 1984-07-31 | 1986-02-25 | Toshiba Electric Equip Corp | 集合住宅用インタ−ホン装置 |
JPS62253161A (ja) | 1986-01-29 | 1987-11-04 | Fuji Photo Film Co Ltd | カラ−画像形成法 |
US4845225A (en) | 1986-04-09 | 1989-07-04 | Ortho Pharmaceutical Corporation | Substituted thiacycloalkeno [3,2-b] pyridines |
US4777167A (en) * | 1986-04-09 | 1988-10-11 | Ortho Pharmaceutical Corporation | Pharmaceutically useful substituted thiacycloalkeno [3,2-b]pyridines, compositions and method of use |
US4879384A (en) | 1988-06-15 | 1989-11-07 | Ortho Pharmaceutical Corporation | Preparation of thiocycloalkno [3,2-b] pyridines |
US5075440A (en) * | 1990-05-03 | 1991-12-24 | Ortho Pharmaceutical Corporation | Novel pyrido[2,3-f](1,4)thiazepines and pyrido[3,2-b](1,5)benzothiazepines |
DE19532320A1 (de) | 1995-09-01 | 1997-03-06 | Bayer Ag | Verfahren zur Herstellung von optisch aktiven ortho-substituierten 4-Aryl-Dihydropyridinen |
AU771033B2 (en) * | 1999-06-14 | 2004-03-11 | Ortho-Mcneil Pharmaceutical, Inc. | Dithiepino(6,5-b)pyridines, and related compositions and methods |
-
2000
- 2000-06-23 IL IL14754000A patent/IL147540A0/xx not_active IP Right Cessation
- 2000-06-23 KR KR1020027000454A patent/KR20020012308A/ko not_active Application Discontinuation
- 2000-06-23 HU HU0202265A patent/HUP0202265A3/hu unknown
- 2000-06-23 ES ES00953634T patent/ES2246248T3/es not_active Expired - Lifetime
- 2000-06-23 JP JP2001509733A patent/JP2003504373A/ja active Pending
- 2000-06-23 DK DK00953634T patent/DK1200446T3/da active
- 2000-06-23 WO PCT/US2000/017310 patent/WO2001004124A1/en not_active Application Discontinuation
- 2000-06-23 CZ CZ2002126A patent/CZ2002126A3/cs unknown
- 2000-06-23 MX MXPA02000436A patent/MXPA02000436A/es active IP Right Grant
- 2000-06-23 CA CA002379199A patent/CA2379199A1/en not_active Abandoned
- 2000-06-23 RU RU2002103384/04A patent/RU2257388C2/ru not_active IP Right Cessation
- 2000-06-23 US US09/603,262 patent/US6476022B1/en not_active Expired - Lifetime
- 2000-06-23 AT AT00953634T patent/ATE302206T1/de not_active IP Right Cessation
- 2000-06-23 BR BR0012386-2A patent/BR0012386A/pt not_active IP Right Cessation
- 2000-06-23 EP EP00953634A patent/EP1200446B1/en not_active Expired - Lifetime
- 2000-06-23 DE DE60022056T patent/DE60022056T2/de not_active Expired - Fee Related
- 2000-06-23 AU AU66050/00A patent/AU779498B2/en not_active Ceased
- 2000-06-23 CN CNB008124957A patent/CN1188416C/zh not_active Expired - Fee Related
- 2000-06-23 PL PL00352760A patent/PL352760A1/xx not_active Application Discontinuation
- 2000-07-11 AR ARP000103544A patent/AR030396A1/es not_active Application Discontinuation
- 2000-09-01 TW TW089113806A patent/TWI256394B/zh not_active IP Right Cessation
-
2002
- 2002-01-09 IL IL147540A patent/IL147540A/en unknown
- 2002-09-20 HK HK02106888.0A patent/HK1045506B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US6476022B1 (en) | 2002-11-05 |
CA2379199A1 (en) | 2001-01-18 |
WO2001004124A1 (en) | 2001-01-18 |
MXPA02000436A (es) | 2002-10-11 |
KR20020012308A (ko) | 2002-02-15 |
DE60022056D1 (de) | 2005-09-22 |
AR030396A1 (es) | 2003-08-20 |
IL147540A (en) | 2006-12-10 |
EP1200446B1 (en) | 2005-08-17 |
ATE302206T1 (de) | 2005-09-15 |
EP1200446A1 (en) | 2002-05-02 |
ES2246248T3 (es) | 2006-02-16 |
RU2257388C2 (ru) | 2005-07-27 |
HUP0202265A3 (en) | 2004-12-28 |
DE60022056T2 (de) | 2006-06-08 |
IL147540A0 (en) | 2002-08-14 |
DK1200446T3 (da) | 2005-10-24 |
CN1372563A (zh) | 2002-10-02 |
HK1045506A1 (en) | 2002-11-29 |
HUP0202265A2 (en) | 2002-10-28 |
AU6605000A (en) | 2001-01-30 |
PL352760A1 (en) | 2003-09-08 |
TWI256394B (en) | 2006-06-11 |
CZ2002126A3 (cs) | 2003-04-16 |
AU779498B2 (en) | 2005-01-27 |
HK1045506B (zh) | 2006-02-03 |
JP2003504373A (ja) | 2003-02-04 |
CN1188416C (zh) | 2005-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009. |