BR0009775A - Método para melhorar a migração e invasão de mioblastos no contexto de terapia genética - Google Patents

Método para melhorar a migração e invasão de mioblastos no contexto de terapia genética

Info

Publication number
BR0009775A
BR0009775A BR0009775-6A BR0009775A BR0009775A BR 0009775 A BR0009775 A BR 0009775A BR 0009775 A BR0009775 A BR 0009775A BR 0009775 A BR0009775 A BR 0009775A
Authority
BR
Brazil
Prior art keywords
migration
invasion
context
myoblasts
improve
Prior art date
Application number
BR0009775-6A
Other languages
English (en)
Inventor
Kotoku Kurachi
Original Assignee
Universtiy Of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23127762&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0009775(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Universtiy Of Michigan filed Critical Universtiy Of Michigan
Publication of BR0009775A publication Critical patent/BR0009775A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Microbiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"MéTODO PARA MELHORAR A MIGRAçãO E INVASãO DE MIOBLASTOS NO CONTEXTO DE TERAPIA GENéTICA". A presente invenção refere-se a uma nova composição derivada empiricamente de citocinas e mioblastos, que possibilita a migração de mioblastos através de barreiras conectivas, e a método que empregam a composição na migração in vivo de mioblastos para fins terapêuticos e terapia genética, bem como a métodos para a identificação de agentes que são agonistas ou antagonistas à migração de mioblastos in vitro ou in vivo.
BR0009775-6A 1999-04-16 2000-02-09 Método para melhorar a migração e invasão de mioblastos no contexto de terapia genética BR0009775A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/293,125 US6284242B1 (en) 1999-04-16 1999-04-16 Method for enhancing myoblast migration and invasion in the context of gene therapy
PCT/US2000/003409 WO2000063396A1 (en) 1999-04-16 2000-02-09 Method for enhancing myoblast migration and invasion in the context of gene therapy

Publications (1)

Publication Number Publication Date
BR0009775A true BR0009775A (pt) 2002-12-31

Family

ID=23127762

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0009775-6A BR0009775A (pt) 1999-04-16 2000-02-09 Método para melhorar a migração e invasão de mioblastos no contexto de terapia genética

Country Status (7)

Country Link
US (2) US6284242B1 (pt)
EP (1) EP1171616A4 (pt)
JP (1) JP2002542265A (pt)
AU (1) AU3593800A (pt)
BR (1) BR0009775A (pt)
CA (1) CA2370527A1 (pt)
WO (1) WO2000063396A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998017784A1 (en) * 1996-10-18 1998-04-30 Universite Laval Method for in vitro preconditioning of myoblasts before transplantation
AU2003220562A1 (en) * 2002-04-01 2003-10-20 Peter K. Law Cellular transplantation for heart regeneration
WO2004030706A2 (en) * 2002-10-01 2004-04-15 Law Peter K Bioactive implants
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
WO2005099758A2 (en) * 2004-04-17 2005-10-27 The Board Of Trustees The Leland Standford Junior University Injectable bioartificial tissue matrix
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7828711B2 (en) 2004-08-16 2010-11-09 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular growth and regeneration using ventricular assist device
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US20110301228A1 (en) * 2009-02-11 2011-12-08 The University Of North Carolina At Chapel Hill Gene therapy vector for treatment of steroid glaucoma

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5833978A (en) * 1995-03-16 1998-11-10 Universite Laval Method of in vitro preconditioning healthy donor's myoblasts before transplantation thereof in compatible patients suffering of recessive myopathies like muscular dystrophy, for improving transplantation success
WO1998017784A1 (en) * 1996-10-18 1998-04-30 Universite Laval Method for in vitro preconditioning of myoblasts before transplantation

Also Published As

Publication number Publication date
EP1171616A4 (en) 2002-07-17
AU3593800A (en) 2000-11-02
JP2002542265A (ja) 2002-12-10
WO2000063396A1 (en) 2000-10-26
US20010055590A1 (en) 2001-12-27
US6284242B1 (en) 2001-09-04
CA2370527A1 (en) 2000-10-26
EP1171616A1 (en) 2002-01-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1925 DE 27/11/2007.