BR0008711A - Encapsulação de complexos bioativos em lipossomas - Google Patents

Encapsulação de complexos bioativos em lipossomas

Info

Publication number
BR0008711A
BR0008711A BR0008711-4A BR0008711A BR0008711A BR 0008711 A BR0008711 A BR 0008711A BR 0008711 A BR0008711 A BR 0008711A BR 0008711 A BR0008711 A BR 0008711A
Authority
BR
Brazil
Prior art keywords
liposomes
encapsulation
bioactive
complexes
nucleic acids
Prior art date
Application number
BR0008711-4A
Other languages
English (en)
Inventor
Paul Meers
Tong Shangguan
Donna Cabral-Lilly
Andrew Janoff
Patrick Ahl
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of BR0008711A publication Critical patent/BR0008711A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

"ENCAPSULAçãO DE COMPLEXOS BIOATIVOS EM LIPOSSOMAS". Esta invenção fornece um método para preparar agentes bioativos encapsuladas por lipossomas tal como ácidos nucléicos, compreendendo complexação dos agentes bioativos em micelas reversas antes da formação de Lipossomas, bem como métodos de uso nos lipossomas então formados e formulações para liberar ácidos nucléicos para as células.
BR0008711-4A 1999-03-02 2000-03-01 Encapsulação de complexos bioativos em lipossomas BR0008711A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12236599P 1999-03-02 1999-03-02
PCT/US2000/005395 WO2000051565A1 (en) 1999-03-02 2000-03-01 Encapsulation of bioactive complexes in liposomes

Publications (1)

Publication Number Publication Date
BR0008711A true BR0008711A (pt) 2002-10-01

Family

ID=22402271

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008711-4A BR0008711A (pt) 1999-03-02 2000-03-01 Encapsulação de complexos bioativos em lipossomas

Country Status (20)

Country Link
US (2) US7491409B1 (pt)
EP (1) EP1156783B1 (pt)
JP (1) JP2002538096A (pt)
KR (1) KR20010112301A (pt)
CN (1) CN1349402A (pt)
AT (1) ATE376413T1 (pt)
AU (1) AU3715900A (pt)
BR (1) BR0008711A (pt)
CA (1) CA2362485A1 (pt)
CZ (1) CZ20013103A3 (pt)
DE (1) DE60036861T2 (pt)
EA (1) EA200100856A1 (pt)
ES (1) ES2295018T3 (pt)
HU (1) HUP0200114A2 (pt)
IL (1) IL145117A0 (pt)
NO (1) NO20014231L (pt)
NZ (1) NZ513829A (pt)
PL (1) PL351487A1 (pt)
WO (1) WO2000051565A1 (pt)
ZA (1) ZA200107205B (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20013103A3 (cs) * 1999-03-02 2002-01-16 The Liposome Company, Inc. Způsob zapouzdřování bioaktivních komplexů do liposomů
AU9418501A (en) * 2000-10-04 2002-04-15 Kyowa Hakko Kogyo Kk Method of coating fine particle with lipid film
WO2002080981A2 (en) * 2001-04-04 2002-10-17 Nordic Vaccine Technology A/S Polynucleotide binding complexes comprising sterols and saponins
US7713942B2 (en) 2001-04-04 2010-05-11 Nordic Vaccine Technology A/S Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
JP4370451B2 (ja) * 2001-09-28 2009-11-25 大塚製薬株式会社 医薬組成物
EP1478341A4 (en) * 2002-01-09 2009-05-20 Transave Inc EFFICIENT ENCAPSULATION OF NUCLEIC ACIDS IN MEDIUM SIZE LIPOSOMES
CA2471918A1 (en) * 2002-01-09 2003-07-24 Elan Pharmaceuticals, Inc. Efficient liposomal encapsulation under mild conditions
AU2003220119A1 (en) 2002-03-07 2003-09-22 University Of Delaware Methods, compositions, and kits for enhancing oligonucleotide-mediated nucleic acid sequence alteration using compositions comprising a histone deacetylase inhibitor, lambda phage beta protein, or hydroxyurea
JP2005529959A (ja) * 2002-06-14 2005-10-06 マイラス コーポレイション 細胞へのポリヌクレオチドの伝達をするための新規な方法
JP5085313B2 (ja) * 2005-01-28 2012-11-28 協和発酵キリン株式会社 被覆微粒子の製造方法
WO2006101201A1 (ja) * 2005-03-24 2006-09-28 National University Corporation Hokkaido University 目的物質を効率的に核内に送達可能なリポソーム
EP1930436B1 (en) * 2005-09-30 2011-04-27 National University Corporation Hokkaido University Vector for delivering target substance into nucleus or cell
US20100143937A1 (en) * 2007-05-31 2010-06-10 Sanofi-Aventis ASSAY METHODS FOR IDENTIFYING AGENTS THAT MODIFY THE ACTIVITY OF NAPE-PLD OR Abh4
US8784659B2 (en) 2007-08-08 2014-07-22 General Electric Company Method for controlling microbial biofilm in aqueous systems
AU2009238175C1 (en) 2008-04-15 2023-11-30 Arbutus Biopharma Corporation Novel lipid formulations for nucleic acid delivery
HUE037082T2 (hu) 2008-11-10 2018-08-28 Arbutus Biopharma Corp Új lipidek és készítmények terápiás hatóanyagok szállítására
CA2767127A1 (en) 2009-07-01 2011-01-06 Protiva Biotherapeutics, Inc. Novel lipid formulations for delivery of therapeutic agents to solid tumors
US20110177147A1 (en) 2010-01-21 2011-07-21 General Electric Company Stable biocidal delivery systems
KR101102834B1 (ko) * 2010-02-24 2012-01-05 충남대학교산학협력단 신규한 리포좀 제조 방법 및 장치
KR101198715B1 (ko) * 2010-05-14 2012-11-13 한국생명공학연구원 핵산 및 친수성 음이온 화합물의 고효율 포획을 위한 비대칭 리포솜 및 이의 제조방법
WO2012000104A1 (en) 2010-06-30 2012-01-05 Protiva Biotherapeutics, Inc. Non-liposomal systems for nucleic acid delivery
FR2964569B1 (fr) * 2010-09-10 2012-10-19 Ct De Cooperation Internationale En Rech Agronomique Pour Le Dev Cirad Nouveaux liposomes de vaccination genique
EP2683410A2 (en) * 2011-03-08 2014-01-15 Access Pharmaceuticals, Inc. Targeted nanocarrier systems for delivery of actives across biological membranes
US9758395B2 (en) 2011-04-28 2017-09-12 Aquero Company, Llc Lysine-based polymer coagulants for use in clarification of process waters
JP6346662B2 (ja) 2013-05-17 2018-06-20 スリーエム イノベイティブ プロパティズ カンパニー 反応混合物、多孔質粒子及び作製方法
CN105209024B (zh) 2013-05-17 2018-04-27 3M创新有限公司 生物活性剂从聚合物复合颗粒的释放
WO2020023311A1 (en) * 2018-07-21 2020-01-30 University Of Tennessee Research Foundation Neutral liposomes containing biologically active agents
AU2020252005A1 (en) * 2019-03-29 2021-11-04 Glycomine Inc. Liposomal formulations, and methods of using and preparing thereof
EP3739321B1 (de) * 2019-05-17 2023-03-08 Xtal Concepts GmbH Qualifizierungsverfahren für kryoelektronenmikroskopie-proben sowie dazugehöriger probenhalter
JPWO2022045009A1 (pt) * 2020-08-24 2022-03-03
EP4314327A1 (en) 2021-03-22 2024-02-07 Illumina Cambridge Limited Methods for improving nucleic acid cluster clonality
CN113785975B (zh) * 2021-09-09 2023-08-29 天津医科大学 精胺、亚精胺脂质体在抗氧化、抗衰老中的应用
DE102022134188B3 (de) 2022-12-20 2024-03-28 Universität Augsburg - Körperschaft des öffentlichen Rechts Verfahren zur in-situ Erfassung von Änderungen eines Lipidsystems bei dessen Lagerung bei einer Lagertemperatur unterhalb von -60 °C

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723147A (en) 1987-02-23 1998-03-03 Depotech Corporation Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
US5286634A (en) * 1989-09-28 1994-02-15 Stadler Joan K Synergistic method for host cell transformation
WO1994023697A1 (en) * 1993-04-22 1994-10-27 Depotech Corporation Cyclodextrin liposomes encapsulating pharmacologic compounds and methods for their use
US5795587A (en) * 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
JP2001510457A (ja) * 1996-11-12 2001-07-31 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア インビボ送達に有効な、脂質―核酸複合体の安定な製剤の調製
CZ20013103A3 (cs) * 1999-03-02 2002-01-16 The Liposome Company, Inc. Způsob zapouzdřování bioaktivních komplexů do liposomů

Also Published As

Publication number Publication date
HUP0200114A2 (hu) 2002-05-29
US7491409B1 (en) 2009-02-17
KR20010112301A (ko) 2001-12-20
WO2000051565A1 (en) 2000-09-08
EP1156783A4 (en) 2003-05-21
NZ513829A (en) 2001-09-28
CN1349402A (zh) 2002-05-15
DE60036861T2 (de) 2008-07-24
EP1156783B1 (en) 2007-10-24
EA200100856A1 (ru) 2002-02-28
EP1156783A1 (en) 2001-11-28
US20090068256A1 (en) 2009-03-12
IL145117A0 (en) 2002-06-30
NO20014231L (no) 2001-10-03
CA2362485A1 (en) 2000-09-08
ZA200107205B (en) 2002-12-02
AU3715900A (en) 2000-09-21
CZ20013103A3 (cs) 2002-01-16
PL351487A1 (en) 2003-04-22
WO2000051565A9 (en) 2002-02-14
DE60036861D1 (de) 2007-12-06
NO20014231D0 (no) 2001-08-31
ES2295018T3 (es) 2008-04-16
JP2002538096A (ja) 2002-11-12
ATE376413T1 (de) 2007-11-15

Similar Documents

Publication Publication Date Title
BR0008711A (pt) Encapsulação de complexos bioativos em lipossomas
BR0314354A (pt) Formação para gentes lipofìlicos
IL140710A0 (en) Pulmonary delivery of active agents
PT1093819E (pt) Compostos e composicoes para fornecimento de agentes activos
AU8533101A (en) Phosphate derivatives as immunoregulatory agents
WO2002038105A3 (en) Novel polyamine analog-amino acid conjugates useful as anticancer agents
ATE355826T1 (de) Verfahren zur verkapselung von nukleinsäuren in lipiddoppelschichten
WO2000040203A3 (en) Polymeric delivery agents and delivery agent compounds
BR0112311A (pt) Compostos e composições para liberar agentes ativos, forma de dosagem unitária, método para preparar ditas composições e seu uso
FR2811552B1 (fr) Composition notamment cosmetique ou pharmaceutique se presentant sous forme solide
CA2333601A1 (en) Surfactant for use in external preparations for skin and external preparation for skin containing the same
DE60003938D1 (de) Wirkstoffe in hydrogel-mikroperlen
FR2827192B1 (fr) Preparations contenant des agents tensio-actifs non ioniques comme agents d'extraction
HUP0301211A3 (en) Haemostatically active preparation containing vwf and method for the production thereof
WO2000053231A3 (en) Fatty acid-anticancer conjugates and uses thereof
EP1295611A4 (en) COMPOUNDS FOR THE TRANSFER OF OLIGONUCLEOTIDES (03.01.02)
ITMI20001591A0 (it) Processo per la preparazione di 2-fenil-imidazo (1,2-a)lpiridini-3-acetammidi
AR025731A1 (es) "ditiepino [6,5-b] piridinas benzo-fusionadas y composiciones y metodos relacionados"
IT1319168B1 (it) Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono.
SE9902742D0 (sv) New pharmaceutical formultion
HK1062139A1 (en) Compositions for improving lipids in blood
ATE397615T1 (de) 6-o-alkyl-2-nor-2-substituierte ketolidderivate
IT1316152B1 (it) Metodo e impianto per la preparazione e distribuzione di farmacicitostatici.
ES2179730A1 (es) Uso de combinaciones de acidos dicarboxilicos de bajo peso molecular, de sus monoesteres y de sus carboxilatos, para la elaboracion de productos agricolas.
ID29944A (id) Formulasi yang ditingkatkan untuk pemberian topikal in vivo non-invasif

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A , 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 NA RPI2003 DE 26/05/2009.