BR0008468A - Método para fertilização humana in vitro, uso de um hormÈnio hipotalânico e/ou hormÈnio pituitário ou de um agonista ou antagonista do mesmo ou de um derivado ativo do mesmo, kit farmacêutico em forma de dosagem única, e, qualquer novo aspecto ou combinação de aspectos - Google Patents

Método para fertilização humana in vitro, uso de um hormÈnio hipotalânico e/ou hormÈnio pituitário ou de um agonista ou antagonista do mesmo ou de um derivado ativo do mesmo, kit farmacêutico em forma de dosagem única, e, qualquer novo aspecto ou combinação de aspectos

Info

Publication number
BR0008468A
BR0008468A BR0008468-9A BR0008468A BR0008468A BR 0008468 A BR0008468 A BR 0008468A BR 0008468 A BR0008468 A BR 0008468A BR 0008468 A BR0008468 A BR 0008468A
Authority
BR
Brazil
Prior art keywords
hormone
same
agonist
antagonist
aspects
Prior art date
Application number
BR0008468-9A
Other languages
English (en)
Inventor
Christian Grondahl
Thomas Host Hansen
Alexander Ruebig
Christa Hegele-Hartung
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of BR0008468A publication Critical patent/BR0008468A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0609—Oocytes, oogonia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C12N2501/392—Sexual steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/10—Conditioning of cells for in vitro fecondation or nuclear transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"MéTODO PARA FERTILIZAçãO HUMANA IN VITRO, USO DE UM HORMÈNIO HIPOTALâMICO E/OU HORMÈNIO PITUITáRIO OU DE UM AGONISTA OU ANTAGONISTA DO MESMO OU DE UM DERIVADO ATIVO DO MESMO, KIT FARMACêUTICO EM FORMA DE DOSAGEM úNICA, E, QUALQUER NOVO ASPECTO OU COMBINAçãO DE ASPECTOS". A fertilização in vitro pode ser aperfeiçoada adicionando-se um composto ativador da meiose.
BR0008468-9A 1999-02-24 2000-02-23 Método para fertilização humana in vitro, uso de um hormÈnio hipotalânico e/ou hormÈnio pituitário ou de um agonista ou antagonista do mesmo ou de um derivado ativo do mesmo, kit farmacêutico em forma de dosagem única, e, qualquer novo aspecto ou combinação de aspectos BR0008468A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA199900255 1999-02-24
US13081699P 1999-04-23 1999-04-23
DKPA199901310 1999-09-16
PCT/DK2000/000074 WO2000050066A1 (en) 1999-02-24 2000-02-23 Treatment of infertility

Publications (1)

Publication Number Publication Date
BR0008468A true BR0008468A (pt) 2002-02-05

Family

ID=27220546

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008468-9A BR0008468A (pt) 1999-02-24 2000-02-23 Método para fertilização humana in vitro, uso de um hormÈnio hipotalânico e/ou hormÈnio pituitário ou de um agonista ou antagonista do mesmo ou de um derivado ativo do mesmo, kit farmacêutico em forma de dosagem única, e, qualquer novo aspecto ou combinação de aspectos

Country Status (13)

Country Link
US (1) US6585982B1 (pt)
EP (1) EP1156822B1 (pt)
JP (1) JP2002537349A (pt)
KR (1) KR20010093280A (pt)
CN (1) CN1353617A (pt)
AT (1) ATE317266T1 (pt)
AU (1) AU2794100A (pt)
BR (1) BR0008468A (pt)
CZ (1) CZ20012967A3 (pt)
DE (1) DE60025905T2 (pt)
ES (1) ES2258445T3 (pt)
HU (1) HUP0200157A3 (pt)
WO (1) WO2000050066A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
EP1157096A2 (en) * 1999-02-26 2001-11-28 Novo Nordisk A/S Culture medium comprising meiosis activating sterols (mas) and method for invitro fertilisation
AU3376501A (en) * 2000-02-25 2001-09-03 Novo Nordisk A/S Improvement of implantation rate
CA2399036A1 (en) * 2000-02-25 2001-08-30 Schering Aktiengesellschaft Improvement of implantation rate
EP1285058A2 (en) * 2000-05-18 2003-02-26 Schering Aktiengesellschaft Fertilization of aged oocytes
EP1287033A2 (en) * 2000-05-25 2003-03-05 Queen's University At Kingston Pt32 sperm protein, sperm c-yes, oocyte cytoplasmic c-yes, and uses thereof
EP1216701A1 (en) * 2000-12-22 2002-06-26 Schering Aktiengesellschaft Process to increase the concentration of meiosis-activating sterols (MAS) in the cholesterol synthesis and the use of potent inhibitors in the process
EP1245572A1 (en) 2001-03-26 2002-10-02 Schering Aktiengesellschaft Aminosterol compounds, their use in the preparation of meiosis-regulating medicaments and method for their preparation
DK1425033T3 (da) * 2001-09-12 2011-01-10 Merck Serono Sa Anvendelse af hCG og LH i styret ovariestimulation
IL160780A0 (en) 2001-09-12 2004-08-31 Applied Research Systems USE OF hCG IN THE MANUFACTURE OF A MEDICAMENT
AU2002324183B2 (en) * 2001-09-12 2007-10-25 Merck Serono Sa Use of hCG and LH in controlled ovarian hyperstimulation
WO2003070766A2 (en) * 2002-02-22 2003-08-28 Novo Nordisk A/S A transducer of mas signalling
JP2005518823A (ja) 2002-03-08 2005-06-30 マクギル・ユニバーシテイ 未成熟ヒト卵母細胞の体外成熟
EA009371B1 (ru) * 2002-06-07 2007-12-28 Арес Трейдинг С.А. Способ управляемой гиперстимуляции яичников и фармацевтический набор для использования в таком способе
PL1765085T3 (pl) 2004-05-17 2015-11-30 Massachusetts Gen Hospital Kompozycje zawierające komórki macierzyste żeńskiej linii germinalnej i sposoby ich zastosowania
EP2422803A3 (en) 2006-03-07 2013-03-13 Geeta Shroff Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation
NZ706806A (en) 2011-04-14 2016-12-23 Gen Hospital Corp Compositions and methods for autologous germline mitochondrial energy transfer
EP3495470A1 (en) 2011-06-29 2019-06-12 The General Hospital Corporation In vivo methods for enhancing bioenergetic status in female germ cells
US20150272622A1 (en) 2011-12-22 2015-10-01 Previvo Genetics, Llc Recovery and processing of human embryos formed in vivo

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5563059A (en) * 1993-02-23 1996-10-08 Genentech, Inc. Use of human inhibin and human activin to increase the number of mature primate oocytes
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
PL322106A1 (en) * 1995-03-06 1998-01-05 Novo Nordisk As Meiosis stimulation
WO1997000884A1 (en) * 1995-06-23 1997-01-09 Novo Nordisk A/S Meiosis regulating compounds
AU6122696A (en) * 1995-06-23 1997-01-22 Novo Nordisk A/S Meiosis regulating compounds
DE69721304T2 (de) * 1996-12-20 2004-03-04 Novo Nordisk A/S Verbindungen zur Regulierung der Meiose
CA2289524A1 (en) * 1997-06-04 1998-12-10 Akzo Nobel Nv 17.beta.-allyloxy(thio)alkyl-androstane derivatives for the modulation of meiosis
US5866599A (en) * 1997-06-06 1999-02-02 Basf Aktiengesellschaft Fungicidal mixtures
CA2363074A1 (en) * 1999-02-24 2000-08-31 Novo Nordisk A/S Treatment of infertility

Also Published As

Publication number Publication date
KR20010093280A (ko) 2001-10-27
CN1353617A (zh) 2002-06-12
JP2002537349A (ja) 2002-11-05
DE60025905D1 (de) 2006-04-20
WO2000050066A1 (en) 2000-08-31
EP1156822A1 (en) 2001-11-28
AU2794100A (en) 2000-09-14
US6585982B1 (en) 2003-07-01
CZ20012967A3 (cs) 2001-12-12
ES2258445T3 (es) 2006-09-01
ATE317266T1 (de) 2006-02-15
HUP0200157A2 (hu) 2002-05-29
HUP0200157A3 (en) 2002-06-28
EP1156822B1 (en) 2006-02-08
DE60025905T2 (de) 2006-09-14

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 4A, 5A, 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1925 DE 27/11/2007.