BR0007993A - Método para identificar um composto que inibe abiossìntese do triptofano, inibidor herbicida,métodos para identificar um composto que podeinibir a triptofano sintase (ts), e para identificaruma proteìna variante de triptofano sintase (ts)resistente a herbicida potencial, ensaios in vitropara quantificar uma reação de tsalfa, e umareação de tsbeta, e, método para identificar umorganismo expressando uma proteìna variante detriptofano sintase (ts) resistente a herbicidapotencial - Google Patents
Método para identificar um composto que inibe abiossìntese do triptofano, inibidor herbicida,métodos para identificar um composto que podeinibir a triptofano sintase (ts), e para identificaruma proteìna variante de triptofano sintase (ts)resistente a herbicida potencial, ensaios in vitropara quantificar uma reação de tsalfa, e umareação de tsbeta, e, método para identificar umorganismo expressando uma proteìna variante detriptofano sintase (ts) resistente a herbicidapotencialInfo
- Publication number
- BR0007993A BR0007993A BR0007993-6A BR0007993A BR0007993A BR 0007993 A BR0007993 A BR 0007993A BR 0007993 A BR0007993 A BR 0007993A BR 0007993 A BR0007993 A BR 0007993A
- Authority
- BR
- Brazil
- Prior art keywords
- identifying
- methods
- resistant
- tryptophan
- reaction
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 9
- 239000004009 herbicide Substances 0.000 title abstract 8
- 230000002363 herbicidal effect Effects 0.000 title abstract 5
- 108010075344 Tryptophan synthase Proteins 0.000 title abstract 4
- 238000006243 chemical reaction Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 title abstract 3
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000000099 in vitro assay Methods 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 4
- 241000196324 Embryophyta Species 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
"MéTODO PARA IDENTIFICAR UM COMPOSTO QUE INIBE ABIOSSìNTESE DO TRIPTOFANO, INIBIDOR HERBICIDA,MéTODOS PARA IDENTIFICAR UM COMPOSTO QUE PODEINIBIR A TRIPTOFANO SINTASE (TS), E PARA IDENTIFICARUMA PROTEìNA VARIANTE DE TRIPTOFANO SINTASE (TS)RESISTENTE A HERBICIDA POTENCIAL, ENSAIOS IN VITROPARA QUANTIFICAR UMA REAçãO DE TSalfa, E UMA REAçãODE TSbeta, E, MéTODO PARA IDENTIFICAR UM ORGANISMOEXPRESSANDO UMA PROTEìNA VARIANTE DE TRIPTOFANOSINTASE (TS) RESISTENTE A HERBICIDA POTENCIAL". Ainvenção refere-se a métodos de identificar inibidores da triptofanosintase (TS), que são úteis como herbicidas, herbicidas inibidoresda TS, métodos de projetar variantes de enzima de TS que sãoresistentes aos herbicidas da invenção e outros herbicidasconhecidos, as próprias variantes de enzima TS, polinucleotídeoscodificando estas variantes de enzima TS, plantas expressando asvariantes de enzima TS e métodos de controle de ervas daninhas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11920899P | 1999-02-05 | 1999-02-05 | |
| PCT/US2000/003188 WO2000046394A2 (en) | 1999-02-05 | 2000-02-04 | Tryptophan synthase as a site of herbicide action |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0007993A true BR0007993A (pt) | 2001-10-30 |
Family
ID=22383118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0007993-6A BR0007993A (pt) | 1999-02-05 | 2000-02-04 | Método para identificar um composto que inibe abiossìntese do triptofano, inibidor herbicida,métodos para identificar um composto que podeinibir a triptofano sintase (ts), e para identificaruma proteìna variante de triptofano sintase (ts)resistente a herbicida potencial, ensaios in vitropara quantificar uma reação de tsalfa, e umareação de tsbeta, e, método para identificar umorganismo expressando uma proteìna variante detriptofano sintase (ts) resistente a herbicidapotencial |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20050050594A1 (pt) |
| EP (1) | EP1144672A3 (pt) |
| JP (1) | JP2003529320A (pt) |
| CN (1) | CN1371428A (pt) |
| AU (1) | AU3484600A (pt) |
| BR (1) | BR0007993A (pt) |
| CA (1) | CA2361703A1 (pt) |
| IL (1) | IL144332A0 (pt) |
| WO (1) | WO2000046394A2 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003078613A2 (de) * | 2002-03-20 | 2003-09-25 | Basf Aktiengesellschaft | Serin hydroxymethyltransferase als target für herbizide |
| ES2657240T3 (es) * | 2009-01-09 | 2018-03-02 | Sigma-Aldrich Co. Llc | Procedimiento de síntesis de beta glicerol fosfato |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635449A (en) * | 1995-04-07 | 1997-06-03 | American Cyanamid Company | Arylthioalkyl- and arylthioalkenylphosphonic acids and derivatives thereof useful as herbicidal agents |
| US5853973A (en) * | 1995-04-20 | 1998-12-29 | American Cyanamid Company | Structure based designed herbicide resistant products |
| WO1999049058A2 (en) * | 1998-03-26 | 1999-09-30 | E.I. Du Pont De Nemours And Company | Tryptophan biosynthetic enzymes |
-
2000
- 2000-02-04 AU AU34846/00A patent/AU3484600A/en not_active Abandoned
- 2000-02-04 CN CN00804650.6A patent/CN1371428A/zh active Pending
- 2000-02-04 WO PCT/US2000/003188 patent/WO2000046394A2/en not_active Application Discontinuation
- 2000-02-04 CA CA002361703A patent/CA2361703A1/en not_active Abandoned
- 2000-02-04 IL IL14433200A patent/IL144332A0/xx unknown
- 2000-02-04 JP JP2000597453A patent/JP2003529320A/ja not_active Withdrawn
- 2000-02-04 BR BR0007993-6A patent/BR0007993A/pt not_active IP Right Cessation
- 2000-02-04 EP EP00913389A patent/EP1144672A3/en not_active Withdrawn
-
2004
- 2004-04-06 US US10/818,451 patent/US20050050594A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000046394A9 (en) | 2001-10-18 |
| WO2000046394A2 (en) | 2000-08-10 |
| CA2361703A1 (en) | 2000-08-10 |
| AU3484600A (en) | 2000-08-25 |
| CN1371428A (zh) | 2002-09-25 |
| US20050050594A1 (en) | 2005-03-03 |
| EP1144672A3 (en) | 2002-03-27 |
| EP1144672A2 (en) | 2001-10-17 |
| WO2000046394A3 (en) | 2000-12-21 |
| IL144332A0 (en) | 2002-05-23 |
| JP2003529320A (ja) | 2003-10-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1929 DE 26/12/2007. |