BR0007993A - Método para identificar um composto que inibe abiossìntese do triptofano, inibidor herbicida,métodos para identificar um composto que podeinibir a triptofano sintase (ts), e para identificaruma proteìna variante de triptofano sintase (ts)resistente a herbicida potencial, ensaios in vitropara quantificar uma reação de tsalfa, e umareação de tsbeta, e, método para identificar umorganismo expressando uma proteìna variante detriptofano sintase (ts) resistente a herbicidapotencial - Google Patents
Método para identificar um composto que inibe abiossìntese do triptofano, inibidor herbicida,métodos para identificar um composto que podeinibir a triptofano sintase (ts), e para identificaruma proteìna variante de triptofano sintase (ts)resistente a herbicida potencial, ensaios in vitropara quantificar uma reação de tsalfa, e umareação de tsbeta, e, método para identificar umorganismo expressando uma proteìna variante detriptofano sintase (ts) resistente a herbicidapotencialInfo
- Publication number
- BR0007993A BR0007993A BR0007993-6A BR0007993A BR0007993A BR 0007993 A BR0007993 A BR 0007993A BR 0007993 A BR0007993 A BR 0007993A BR 0007993 A BR0007993 A BR 0007993A
- Authority
- BR
- Brazil
- Prior art keywords
- identifying
- methods
- resistant
- tryptophan
- reaction
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 9
- 239000004009 herbicide Substances 0.000 title abstract 8
- 230000002363 herbicidal effect Effects 0.000 title abstract 5
- 108010075344 Tryptophan synthase Proteins 0.000 title abstract 4
- 238000006243 chemical reaction Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 title abstract 3
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000000099 in vitro assay Methods 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 4
- 241000196324 Embryophyta Species 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
"MéTODO PARA IDENTIFICAR UM COMPOSTO QUE INIBE ABIOSSìNTESE DO TRIPTOFANO, INIBIDOR HERBICIDA,MéTODOS PARA IDENTIFICAR UM COMPOSTO QUE PODEINIBIR A TRIPTOFANO SINTASE (TS), E PARA IDENTIFICARUMA PROTEìNA VARIANTE DE TRIPTOFANO SINTASE (TS)RESISTENTE A HERBICIDA POTENCIAL, ENSAIOS IN VITROPARA QUANTIFICAR UMA REAçãO DE TSalfa, E UMA REAçãODE TSbeta, E, MéTODO PARA IDENTIFICAR UM ORGANISMOEXPRESSANDO UMA PROTEìNA VARIANTE DE TRIPTOFANOSINTASE (TS) RESISTENTE A HERBICIDA POTENCIAL". Ainvenção refere-se a métodos de identificar inibidores da triptofanosintase (TS), que são úteis como herbicidas, herbicidas inibidoresda TS, métodos de projetar variantes de enzima de TS que sãoresistentes aos herbicidas da invenção e outros herbicidasconhecidos, as próprias variantes de enzima TS, polinucleotídeoscodificando estas variantes de enzima TS, plantas expressando asvariantes de enzima TS e métodos de controle de ervas daninhas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11920899P | 1999-02-05 | 1999-02-05 | |
| PCT/US2000/003188 WO2000046394A2 (en) | 1999-02-05 | 2000-02-04 | Tryptophan synthase as a site of herbicide action |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0007993A true BR0007993A (pt) | 2001-10-30 |
Family
ID=22383118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0007993-6A BR0007993A (pt) | 1999-02-05 | 2000-02-04 | Método para identificar um composto que inibe abiossìntese do triptofano, inibidor herbicida,métodos para identificar um composto que podeinibir a triptofano sintase (ts), e para identificaruma proteìna variante de triptofano sintase (ts)resistente a herbicida potencial, ensaios in vitropara quantificar uma reação de tsalfa, e umareação de tsbeta, e, método para identificar umorganismo expressando uma proteìna variante detriptofano sintase (ts) resistente a herbicidapotencial |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20050050594A1 (pt) |
| EP (1) | EP1144672A3 (pt) |
| JP (1) | JP2003529320A (pt) |
| CN (1) | CN1371428A (pt) |
| AU (1) | AU3484600A (pt) |
| BR (1) | BR0007993A (pt) |
| CA (1) | CA2361703A1 (pt) |
| IL (1) | IL144332A0 (pt) |
| WO (1) | WO2000046394A2 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7319013B2 (en) * | 2002-03-20 | 2008-01-15 | Basf Aktiengesellschaft | Serine hydroxymethyltransferase as a target for herbicides |
| CN102272080A (zh) * | 2009-01-09 | 2011-12-07 | 西格马-奥利奇有限公司 | β磷酸甘油的合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635449A (en) * | 1995-04-07 | 1997-06-03 | American Cyanamid Company | Arylthioalkyl- and arylthioalkenylphosphonic acids and derivatives thereof useful as herbicidal agents |
| US5853973A (en) * | 1995-04-20 | 1998-12-29 | American Cyanamid Company | Structure based designed herbicide resistant products |
| BR9908101A (pt) * | 1998-03-26 | 2000-12-12 | Du Pont | Fragmento de ácido nucléico isolado codificador de toda ou uma parte substancial de uma sub-unidade alfa e/ou beta de sintase de antranilato, gene quimério, célula hospedeira transformada, polipeptìdeo sub-unidade alfa de sintase de antranilato, método de alteração do nìvel de expressão de uma enzima biossintética de triptofano em uma célula hospedeira, método de obtenção de um fragmento de ácido nucléico codificador de uma parte substancial de uma sequência de aminoácido codificadora de uma enzima biossintética de triptofano e método de avaliação da capacidade de pelo menos um composto em inibir a atividade de uma enzima biossintética de triptofano. |
-
2000
- 2000-02-04 CN CN00804650.6A patent/CN1371428A/zh active Pending
- 2000-02-04 CA CA002361703A patent/CA2361703A1/en not_active Abandoned
- 2000-02-04 IL IL14433200A patent/IL144332A0/xx unknown
- 2000-02-04 AU AU34846/00A patent/AU3484600A/en not_active Abandoned
- 2000-02-04 EP EP00913389A patent/EP1144672A3/en not_active Withdrawn
- 2000-02-04 WO PCT/US2000/003188 patent/WO2000046394A2/en not_active Application Discontinuation
- 2000-02-04 BR BR0007993-6A patent/BR0007993A/pt not_active IP Right Cessation
- 2000-02-04 JP JP2000597453A patent/JP2003529320A/ja not_active Withdrawn
-
2004
- 2004-04-06 US US10/818,451 patent/US20050050594A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003529320A (ja) | 2003-10-07 |
| EP1144672A3 (en) | 2002-03-27 |
| CN1371428A (zh) | 2002-09-25 |
| CA2361703A1 (en) | 2000-08-10 |
| IL144332A0 (en) | 2002-05-23 |
| WO2000046394A3 (en) | 2000-12-21 |
| US20050050594A1 (en) | 2005-03-03 |
| AU3484600A (en) | 2000-08-25 |
| EP1144672A2 (en) | 2001-10-17 |
| WO2000046394A9 (en) | 2001-10-18 |
| WO2000046394A2 (en) | 2000-08-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Galichet et al. | Protein farnesylation in plants—conserved mechanisms but different targets | |
| Hartl et al. | Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis | |
| Gelb et al. | Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics | |
| Field | Green magic: regulation of the chloroplast stress response by (p) ppGpp in plants and algae | |
| Hemsley | The importance of lipid modified proteins in plants | |
| Chiu et al. | ABA‐dependent inhibition of the ubiquitin proteasome system during germination at high temperature in Arabidopsis | |
| Van Ree et al. | Nitric oxide accumulation in Arabidopsis is independent of NOA1 in the presence of sucrose | |
| BRPI0413973A (pt) | compostos | |
| Sim et al. | Analysis of the regulatory and catalytic domains of PTEN‐induced kinase‐1 (PINK1) | |
| WO2003006652A3 (en) | Inhibition of specific histone deacetylase isoforms | |
| EP2287292A3 (en) | Plant derived hydroxy phenyl pyruvate dioxygneases (hppd) resistant against triketone herbicides and transgenic plants containing these dioxygenases | |
| Williams et al. | Two pathways for cysteine biosynthesis in Leishmania major | |
| CR10065A (es) | Pirrol[2,3-b] piridinas y pirrol [2,3-b]pirimidinas heteroarilo sustituidas como inhibidores de quinasas janus | |
| Enayetallah et al. | Effects of human soluble epoxide hydrolase polymorphisms on isoprenoid phosphate hydrolysis | |
| Flohé | The trypanothione system and its implications in the therapy of trypanosomatid diseases | |
| ATE373715T1 (de) | Isoprenoid biosynthese | |
| Servillo et al. | Ophthalmic acid is a marker of oxidative stress in plants as in animals | |
| Loring et al. | Initial kinetic characterization of sterile alpha and toll/interleukin receptor motif-containing protein 1 | |
| BR0317284A (pt) | Inibidores aminocianopiridina de proteìna quinase-2 ativada com proteìna quinase ativada com mitógeno | |
| Rütgers et al. | Not changes in membrane fluidity but proteotoxic stress triggers heat shock protein expression in Chlamydomonas reinhardtii | |
| Nisbett et al. | NosP signaling modulates the NO/H-NOX-mediated multicomponent c-di-GMP network and biofilm formation in Shewanella oneidensis | |
| Rizhsky et al. | Integrating metabolomics and transcriptomics data to discover a biocatalyst that can generate the amine precursors for alkamide biosynthesis | |
| Ieda et al. | An irreversible inhibitor of peptidyl-prolyl cis/trans isomerase Pin1 and evaluation of cytotoxicity | |
| Du | Transcription, DNA damage and beyond: the roles of histone ubiquitination and deubiquitination | |
| WO2002006512A3 (en) | Method for detecting uracil biosynthesis inhibitors and their use as herbicides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1929 DE 26/12/2007. |