BR0005721A - Plasmìdeos de corynebacterium glutamicum e uso dos mesmos - Google Patents
Plasmìdeos de corynebacterium glutamicum e uso dos mesmosInfo
- Publication number
- BR0005721A BR0005721A BR0005721-5A BR0005721A BR0005721A BR 0005721 A BR0005721 A BR 0005721A BR 0005721 A BR0005721 A BR 0005721A BR 0005721 A BR0005721 A BR 0005721A
- Authority
- BR
- Brazil
- Prior art keywords
- plasmids
- seq
- corynebacterium glutamicum
- plasmid
- kbp
- Prior art date
Links
- 239000013612 plasmid Substances 0.000 title abstract 6
- 241000186226 Corynebacterium glutamicum Species 0.000 title abstract 3
- 239000002773 nucleotide Substances 0.000 abstract 3
- 125000003729 nucleotide group Chemical group 0.000 abstract 3
- 230000010076 replication Effects 0.000 abstract 3
- 241000894006 Bacteria Species 0.000 abstract 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 abstract 2
- 150000008575 L-amino acids Chemical class 0.000 abstract 1
- 239000004098 Tetracycline Substances 0.000 abstract 1
- 101150067314 aadA gene Proteins 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000013600 plasmid vector Substances 0.000 abstract 1
- UNFWWIHTNXNPBV-WXKVUWSESA-N spectinomycin Chemical compound O([C@@H]1[C@@H](NC)[C@@H](O)[C@H]([C@@H]([C@H]1O1)O)NC)[C@]2(O)[C@H]1O[C@H](C)CC2=O UNFWWIHTNXNPBV-WXKVUWSESA-N 0.000 abstract 1
- 229960000268 spectinomycin Drugs 0.000 abstract 1
- 229960005322 streptomycin Drugs 0.000 abstract 1
- 101150107585 tetA gene Proteins 0.000 abstract 1
- 229930101283 tetracycline Natural products 0.000 abstract 1
- 229960002180 tetracycline Drugs 0.000 abstract 1
- 235000019364 tetracycline Nutrition 0.000 abstract 1
- 150000003522 tetracyclines Chemical class 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
"PLASMìDEOS DE CORYNEBACTERIUM GLUTAMICUM E USO DOS MESMOS". A invenção refere-se a plasmídeos mutuamente compatíveis pTET3 e pCRY4, isolados da cepa de Corynebacterium glutamicum depositado sob DSM número 5816, em que o plasmídeo pTET3 é caracterizado por: 1.1 um comprimento de ~27,8 kbp e o mapa de restrição mostrado na Figura 1 1.2 uma região de replicação compreendendo a seq³ência de nucleotídeo mostrada em SEQ. ID. NO. 1 e 1.3 uma região de resistência a antibiótico consistindo de um gene tetA que confere resistência à tetraciclina e um gene aadA que confere resistência à estreptomicina e espectinomicina, mostrada em SEQ. ID. NO. 6 e o plasmídeo pCRY4 é caracterizado por: 1.4 um comprimento de ~48 kbp e o mapa de restrição mostrado na Figura 2 e 1.5 uma região de replicação compreendendo a seq³ência de nucleotídeo mostrada em SEQ. ID. NO. 4, a vetores de plasmídeos compostos desses plasmídeos os quais são capazes de replicação autónoma em bactérias corineformes e a processos para a produção de L-aminoácidos, vitaminas e nucleotídeos usando-se essas bactérias.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19953206A DE19953206A1 (de) | 1999-11-05 | 1999-11-05 | Plasmide aus Corynebacterium glutamicum und deren Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0005721A true BR0005721A (pt) | 2002-07-23 |
Family
ID=7927972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0005721-5A BR0005721A (pt) | 1999-11-05 | 2000-11-06 | Plasmìdeos de corynebacterium glutamicum e uso dos mesmos |
Country Status (15)
Country | Link |
---|---|
US (1) | US6777229B1 (pt) |
EP (1) | EP1097998B1 (pt) |
JP (1) | JP2001178480A (pt) |
KR (1) | KR20010070189A (pt) |
CN (1) | CN1295127A (pt) |
AT (1) | ATE394495T1 (pt) |
AU (1) | AU6807700A (pt) |
BR (1) | BR0005721A (pt) |
CA (1) | CA2322657A1 (pt) |
DE (2) | DE19953206A1 (pt) |
HU (1) | HUP0004275A2 (pt) |
ID (1) | ID28192A (pt) |
PL (1) | PL343703A1 (pt) |
SK (1) | SK16462000A3 (pt) |
ZA (1) | ZA200006271B (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002008406A2 (en) * | 2000-07-24 | 2002-01-31 | Degussa Ag | Alanine racemase (alr) of corynebacterium glutamicum |
KR100694389B1 (ko) * | 2004-12-30 | 2007-03-12 | 씨제이 주식회사 | 표적 유전자 변형 원핵 세포 생산 방법 |
DE102010032484A1 (de) * | 2010-07-28 | 2012-02-02 | Evonik Goldschmidt Gmbh | Zellen und Verfahren zur Herstellung von Rhamnolipiden |
CN102191258A (zh) * | 2011-01-27 | 2011-09-21 | 南京农业大学 | 水稻白叶枯病菌抗链霉素检测基因及其检测方法 |
DE102012016716A1 (de) | 2012-08-22 | 2014-02-27 | Forschungszentrum Jülich GmbH | Verfahren zur Herstellung von Vektoren enthaltend ein für in seiner feedback-Inhibierung gemindertes oder ausgeschaltetes Enzym kodierendes Gen und deren Verwendung für die Herstellung von Aminosäuren und Nukleotiden |
CN103374540B (zh) * | 2013-08-13 | 2015-04-22 | 廊坊梅花生物技术开发有限公司 | 谷氨酸棒杆菌及其应用 |
WO2016054792A1 (en) | 2014-10-09 | 2016-04-14 | Cathay R&D Center Co., Ltd. | Expression of recombinant tetracycline efflux pumps for the production of lysine or lysine-derived products, and methods and applications thereof |
CN111019966B (zh) * | 2019-12-26 | 2023-01-24 | 华南农业大学 | 一种具有较高棒状杆菌复制能力的表达质粒及其构建方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4027453A1 (de) | 1990-08-30 | 1992-03-05 | Degussa | Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren |
DE4400926C1 (de) * | 1994-01-14 | 1995-06-01 | Forschungszentrum Juelich Gmbh | Herstellung von L-Isoleucin mittels rekombinanter Mikroorganismen mit deregulierter Threonindehydratase |
-
1999
- 1999-11-05 DE DE19953206A patent/DE19953206A1/de not_active Withdrawn
-
2000
- 2000-10-11 AT AT00122056T patent/ATE394495T1/de not_active IP Right Cessation
- 2000-10-11 DE DE50015143T patent/DE50015143D1/de not_active Expired - Lifetime
- 2000-10-11 EP EP00122056A patent/EP1097998B1/de not_active Expired - Lifetime
- 2000-10-25 AU AU68077/00A patent/AU6807700A/en not_active Abandoned
- 2000-10-27 ID IDP20000925A patent/ID28192A/id unknown
- 2000-10-31 SK SK1646-2000A patent/SK16462000A3/sk unknown
- 2000-11-02 JP JP2000336502A patent/JP2001178480A/ja active Pending
- 2000-11-02 ZA ZA200006271A patent/ZA200006271B/xx unknown
- 2000-11-02 CN CN00130368A patent/CN1295127A/zh active Pending
- 2000-11-02 CA CA002322657A patent/CA2322657A1/en not_active Abandoned
- 2000-11-03 US US09/704,725 patent/US6777229B1/en not_active Expired - Lifetime
- 2000-11-03 HU HU0004275A patent/HUP0004275A2/hu unknown
- 2000-11-03 KR KR1020000065217A patent/KR20010070189A/ko not_active Application Discontinuation
- 2000-11-06 BR BR0005721-5A patent/BR0005721A/pt not_active Application Discontinuation
- 2000-11-06 PL PL00343703A patent/PL343703A1/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US6777229B1 (en) | 2004-08-17 |
HU0004275D0 (pt) | 2001-01-29 |
PL343703A1 (en) | 2001-05-07 |
JP2001178480A (ja) | 2001-07-03 |
ATE394495T1 (de) | 2008-05-15 |
SK16462000A3 (sk) | 2001-12-03 |
DE50015143D1 (de) | 2008-06-19 |
HUP0004275A2 (en) | 2002-09-28 |
KR20010070189A (ko) | 2001-07-25 |
CA2322657A1 (en) | 2001-05-05 |
AU6807700A (en) | 2001-05-10 |
EP1097998B1 (de) | 2008-05-07 |
ID28192A (id) | 2001-05-10 |
CN1295127A (zh) | 2001-05-16 |
EP1097998A1 (de) | 2001-05-09 |
ZA200006271B (en) | 2001-05-25 |
DE19953206A1 (de) | 2001-05-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |