BG62968B1 - N-//1-/4-(4-флорфенокси)бутил/-4-пиперидинил/-n-метиламино/-2- бензотиазололи като антиаритмични средства от клас iii - Google Patents

N-//1-/4-(4-флорфенокси)бутил/-4-пиперидинил/-n-метиламино/-2- бензотиазололи като антиаритмични средства от клас iii Download PDF

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Publication number
BG62968B1
BG62968B1 BG100210A BG10021095A BG62968B1 BG 62968 B1 BG62968 B1 BG 62968B1 BG 100210 A BG100210 A BG 100210A BG 10021095 A BG10021095 A BG 10021095A BG 62968 B1 BG62968 B1 BG 62968B1
Authority
BG
Bulgaria
Prior art keywords
compound
piperidinyl
methylamino
butyl
fluorophenoxy
Prior art date
Application number
BG100210A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100210A (bg
Inventor
Jozef HEYKANTS
Marcel Borgers
Doris Wilhelm
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of BG100210A publication Critical patent/BG100210A/bg
Publication of BG62968B1 publication Critical patent/BG62968B1/bg

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG100210A 1993-06-11 1995-12-08 N-//1-/4-(4-флорфенокси)бутил/-4-пиперидинил/-n-метиламино/-2- бензотиазололи като антиаритмични средства от клас iii BG62968B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201685 1993-06-11
PCT/EP1994/001849 WO1994029305A1 (en) 1993-06-11 1994-06-06 N-[[1-[4-(4-fluorophenoxy)butyl]-4-piperidinyl]-n-methylamino]-2-benzothiazolols as class iii antiarrhythmic agents

Publications (2)

Publication Number Publication Date
BG100210A BG100210A (bg) 1996-07-31
BG62968B1 true BG62968B1 (bg) 2000-12-29

Family

ID=8213890

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100210A BG62968B1 (bg) 1993-06-11 1995-12-08 N-//1-/4-(4-флорфенокси)бутил/-4-пиперидинил/-n-метиламино/-2- бензотиазололи като антиаритмични средства от клас iii

Country Status (34)

Country Link
US (1) US5691354A (de)
EP (1) EP0701556B1 (de)
JP (1) JP3498145B2 (de)
KR (1) KR100337984B1 (de)
CN (1) CN1039120C (de)
AT (1) ATE159254T1 (de)
AU (1) AU678841B2 (de)
BG (1) BG62968B1 (de)
BR (1) BR9406765A (de)
CA (1) CA2163018A1 (de)
CZ (1) CZ285766B6 (de)
DE (1) DE69406284T2 (de)
DK (1) DK0701556T3 (de)
ES (1) ES2108471T3 (de)
FI (1) FI955916A (de)
GR (1) GR3025805T3 (de)
HU (1) HU221620B1 (de)
IL (1) IL109975A (de)
LV (1) LV11544B (de)
MY (1) MY111222A (de)
NO (1) NO305123B1 (de)
NZ (1) NZ268575A (de)
OA (1) OA10201A (de)
PH (1) PH31126A (de)
PL (1) PL176775B1 (de)
RO (1) RO115523B1 (de)
RU (1) RU2122546C1 (de)
SG (1) SG48821A1 (de)
SI (1) SI9420036A (de)
SK (1) SK281175B6 (de)
TW (1) TW282469B (de)
UA (1) UA41936C2 (de)
WO (1) WO1994029305A1 (de)
ZA (1) ZA944106B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0204496A3 (en) 2000-01-20 2004-07-28 Eisai Co Ltd Novel piperidine compounds and pharmaceutical compositions containing the same and process for preparation the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
US4861785A (en) * 1984-12-03 1989-08-29 Janssen Pharmaceutica N.V. Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents
US5010198A (en) * 1984-12-03 1991-04-23 Janssen Pharmaceutica N.V. Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
US4749702A (en) * 1985-04-15 1988-06-07 Janssen Pharmaceutica N. V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol

Also Published As

Publication number Publication date
SI9420036A (en) 1996-10-31
LV11544B (en) 1997-08-20
LV11544A (lv) 1996-10-20
UA41936C2 (uk) 2001-10-15
OA10201A (en) 1996-12-18
PL176775B1 (pl) 1999-07-30
DK0701556T3 (da) 1998-01-26
KR100337984B1 (ko) 2002-10-25
AU7183894A (en) 1995-01-03
US5691354A (en) 1997-11-25
RU2122546C1 (ru) 1998-11-27
BR9406765A (pt) 1996-02-21
NO305123B1 (no) 1999-04-06
AU678841B2 (en) 1997-06-12
SK281175B6 (sk) 2000-12-11
NO954801D0 (no) 1995-11-27
CN1039120C (zh) 1998-07-15
IL109975A (en) 1999-04-11
CZ319295A3 (en) 1996-03-13
ZA944106B (en) 1995-12-11
SK154495A3 (en) 1996-06-05
CN1125443A (zh) 1996-06-26
CA2163018A1 (en) 1994-12-22
HU221620B1 (hu) 2002-12-28
HUT73679A (en) 1996-09-30
CZ285766B6 (cs) 1999-11-17
JP3498145B2 (ja) 2004-02-16
NO954801L (no) 1995-11-27
WO1994029305A1 (en) 1994-12-22
EP0701556A1 (de) 1996-03-20
FI955916A0 (fi) 1995-12-08
FI955916A (fi) 1995-12-08
GR3025805T3 (en) 1998-03-31
HU9501971D0 (en) 1995-09-28
ES2108471T3 (es) 1997-12-16
ATE159254T1 (de) 1997-11-15
TW282469B (de) 1996-08-01
JPH08511014A (ja) 1996-11-19
MY111222A (en) 1999-09-30
DE69406284D1 (de) 1997-11-20
BG100210A (bg) 1996-07-31
PH31126A (en) 1998-02-23
RO115523B1 (ro) 2000-03-30
SG48821A1 (en) 1998-05-18
EP0701556B1 (de) 1997-10-15
PL311965A1 (en) 1996-03-18
IL109975A0 (en) 1994-10-07
NZ268575A (en) 1996-08-27
DE69406284T2 (de) 1998-02-19

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