BG61683B1 - Получаване и използване на убити с формалин организми от видае. coli, експресиращи антиген на колонийобразуващия фактор, заваксиниране срещу чревни инфекции/диарии, причинени отентеротоксични бактерии на e. coli у хората - Google Patents

Получаване и използване на убити с формалин организми от видае. coli, експресиращи антиген на колонийобразуващия фактор, заваксиниране срещу чревни инфекции/диарии, причинени отентеротоксични бактерии на e. coli у хората Download PDF

Info

Publication number
BG61683B1
BG61683B1 BG98070A BG9807093A BG61683B1 BG 61683 B1 BG61683 B1 BG 61683B1 BG 98070 A BG98070 A BG 98070A BG 9807093 A BG9807093 A BG 9807093A BG 61683 B1 BG61683 B1 BG 61683B1
Authority
BG
Bulgaria
Prior art keywords
cfa
coli
bacteria
formalin
colony
Prior art date
Application number
BG98070A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG98070A (bg
Inventor
Jan Holmgren
Ann-Mari Svennerholm
Original Assignee
Jan Holmgren
Ann-Mari Svennerholm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jan Holmgren, Ann-Mari Svennerholm filed Critical Jan Holmgren
Publication of BG98070A publication Critical patent/BG98070A/bg
Publication of BG61683B1 publication Critical patent/BG61683B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG98070A 1991-02-26 1993-08-25 Получаване и използване на убити с формалин организми от видае. coli, експресиращи антиген на колонийобразуващия фактор, заваксиниране срещу чревни инфекции/диарии, причинени отентеротоксични бактерии на e. coli у хората BG61683B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9100556A SE9100556D0 (sv) 1991-02-26 1991-02-26 Preparation and use of formalin-killed colonization-factor-antigen (cfa)-expressing e coli organisms for vaccination against enteric infection/diarrhea caused by enterotoxigenic e coli bacteria in humans
PCT/SE1992/000110 WO1992014487A1 (en) 1991-02-26 1992-02-25 Preparation and use of formalin-killed colonization-factor-antigen (cfa)-expressing e. coli organisms for vaccination against enteric infection/diarrhea caused by enterotoxigenic e. coli bacteria in humans

Publications (2)

Publication Number Publication Date
BG98070A BG98070A (bg) 1994-06-30
BG61683B1 true BG61683B1 (bg) 1998-03-31

Family

ID=20381987

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98070A BG61683B1 (bg) 1991-02-26 1993-08-25 Получаване и използване на убити с формалин организми от видае. coli, експресиращи антиген на колонийобразуващия фактор, заваксиниране срещу чревни инфекции/диарии, причинени отентеротоксични бактерии на e. coli у хората

Country Status (22)

Country Link
US (1) US6558678B1 (sk)
EP (1) EP0573527B1 (sk)
JP (1) JP3169608B2 (sk)
KR (1) KR100221452B1 (sk)
AT (1) ATE170755T1 (sk)
AU (1) AU663864B2 (sk)
BG (1) BG61683B1 (sk)
BR (1) BR9205677A (sk)
CA (1) CA2104877C (sk)
CZ (1) CZ281556B6 (sk)
DE (1) DE69226944T2 (sk)
DK (1) DK0573527T3 (sk)
ES (1) ES2123550T3 (sk)
FI (1) FI108775B (sk)
HU (1) HU213924B (sk)
NO (1) NO307867B1 (sk)
OA (1) OA09865A (sk)
RO (1) RO109819B1 (sk)
RU (1) RU2127121C1 (sk)
SE (1) SE9100556D0 (sk)
SK (1) SK280919B6 (sk)
WO (1) WO1992014487A1 (sk)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118758B1 (en) * 1997-01-24 2006-10-10 The United States Of America As Represented By The Secretary Of The Army Transformed bacteria producing CS6 antigens as vaccines
SE9401921D0 (sv) * 1994-06-03 1994-06-03 Sbl Vaccin Ab A method of cultivating bacteria
US7404961B2 (en) 1996-08-02 2008-07-29 The United States Of America As Represented By The Secretary Of The Army Peptides responsive to antibodies against consensus peptide of the CS4-CFA/I family proteins
US7094883B1 (en) 1996-08-02 2006-08-22 The United States Of America As Represented By The Secretary Of The Army Monoclonal antibody which agglutinates E. coli having the CS4-CFA/I family protein
US5994078A (en) * 1997-07-31 1999-11-30 Maine Medical Center Stable encapsulated reference nucleic acid and method of making
SE515285C2 (sv) * 1998-12-18 2001-07-09 Sbl Vaccin Ab Oralt vaccin mot diarré
GB0121998D0 (en) 2001-09-11 2001-10-31 Acambis Res Ltd Attenuated bacteria useful in vaccines
JP5100122B2 (ja) * 2003-10-31 2012-12-19 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 細菌の病原因子とそれらの使用
CN101378780A (zh) * 2006-02-01 2009-03-04 Sbl疫苗公司 重组细菌中的肠产毒性大肠杆菌定居因子(cf)抗原
JPWO2012157699A1 (ja) * 2011-05-18 2014-07-31 味の素株式会社 動物用免疫賦活剤、それを含む飼料及びその製造方法
US8926980B2 (en) 2011-07-11 2015-01-06 Camas Incorporated Compositions against bacterial toxins
KR101940357B1 (ko) 2011-09-12 2019-01-18 스칸디나비안 바이오파마 홀딩 에이비 세포 표면 상 ｅｔｅｃ ｃｓ６ 항원 제시의 증가 방법 및 그것의 수득가능한 산물들
WO2013037397A1 (en) 2011-09-12 2013-03-21 Scandinavian Biopharma Holding Ab Vaccine for protection against etec induced diarrhea comprising dmlt.
RO132299A3 (ro) 2017-06-06 2018-12-28 Fântână Raul Sorin Compoziţie şi metodă de preparare şi evaluare a unui imunogen complex numit i-spga, destinat producerii de proteine imunologic active ()

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD62894A (sk) *
DE1208038B (de) * 1963-08-01 1965-12-30 Wellcome Found Verfahren zur Herstellung von Impfstoffen gegen Coli-Infektionen
GB1472624A (en) 1974-09-02 1977-05-04 Canadian Patents Dev Enteric disease vaccine
US4338298A (en) * 1980-04-04 1982-07-06 Endowment And Research Foundation At Montana State University Vaccine for passive immunization against enteric colibacillosis and method of use
DK41885A (da) * 1985-01-31 1986-11-13 Slagteriernes Forskningsinst 987p-fimbrie-producerende mikroorganisme, vaccine til immunisering af grise samt fremgangsmaade til fremstilling af vaccinen
DE3650065T2 (de) * 1985-07-31 1995-03-02 Univ Leland Stanford Junior Invasive Mikroorganismen.
FI76484C (fi) 1986-02-03 1988-11-10 Osmo Norvasto Kundstol.
JPS6399020A (ja) 1986-06-05 1988-04-30 ベイラ−　カレツジ　オブ　メデイシン ワクチンとその製法
SU1723116A1 (ru) * 1988-04-15 1992-03-30 Оренбургский Государственный Медицинский Институт Штамм бактерий BacILLUS SUвтILIS, используемый дл получени препарата дл профилактики и лечени воспалительных процессов и аллергических заболеваний
WO1990002484A1 (en) * 1988-09-06 1990-03-22 Washington University Oral immunization by transgenic plants
SE9401921D0 (sv) * 1994-06-03 1994-06-03 Sbl Vaccin Ab A method of cultivating bacteria

Also Published As

Publication number Publication date
BR9205677A (pt) 1994-05-17
HU213924B (en) 1997-11-28
CZ281556B6 (cs) 1996-11-13
RO109819B1 (ro) 1995-06-30
SE9100556D0 (sv) 1991-02-26
ES2123550T3 (es) 1999-01-16
FI933728A0 (fi) 1993-08-25
NO933037L (no) 1993-08-25
US6558678B1 (en) 2003-05-06
OA09865A (en) 1994-08-15
DK0573527T3 (da) 1999-06-07
HUT67198A (en) 1995-02-28
CA2104877A1 (en) 1992-08-27
WO1992014487A1 (en) 1992-09-03
HU9302410D0 (en) 1993-11-29
AU663864B2 (en) 1995-10-26
EP0573527A1 (en) 1993-12-15
DE69226944T2 (de) 1999-02-11
NO307867B1 (no) 2000-06-13
ATE170755T1 (de) 1998-09-15
NO933037D0 (no) 1993-08-25
CA2104877C (en) 2005-10-04
JPH06505730A (ja) 1994-06-30
EP0573527B1 (en) 1998-09-09
SK280919B6 (sk) 2000-09-12
CZ174293A3 (en) 1994-04-13
KR930703015A (ko) 1993-11-29
FI108775B (fi) 2002-03-28
JP3169608B2 (ja) 2001-05-28
KR100221452B1 (ko) 1999-09-15
BG98070A (bg) 1994-06-30
FI933728A (fi) 1993-10-25
RU2127121C1 (ru) 1999-03-10
AU1330892A (en) 1992-09-15
DE69226944D1 (de) 1998-10-15
SK91093A3 (en) 1994-05-11

Similar Documents

Publication Publication Date Title
Holmgren et al. Mechanisms of disease and immunity in cholera: a review
Black et al. Protective efficacy in humans of killed whole-vibrio oral cholera vaccine with and without the B subunit of cholera toxin
CA2198586C (en) Mutant enterotoxin effective as a non-toxic oral adjuvant
Evans et al. Administration of purified colonization factor antigens (CFA/I, CFA/II) of enterotoxigenic Escherichia coli to volunteers: response to challenge with virulent enterotoxigenic Escherichia coli
BG61683B1 (bg) Получаване и използване на убити с формалин организми от видае. coli, експресиращи антиген на колонийобразуващия фактор, заваксиниране срещу чревни инфекции/диарии, причинени отентеротоксични бактерии на e. coli у хората
Holmgren et al. Cross‐reactivity between heat labile enterotoxins of Vibrio cholerae and Escherichia coli in neutralization tests in rabbit ileum and skin
JP3601602B2 (ja) 無毒性微生物及びその使用：サルモネラ
Richardson Animal models in cholera research
Sizemore et al. Enterotoxigenic Escherichia coli virulence factors and vaccine approaches
Lasaro et al. Prime-boost vaccine regimen confers protective immunity to human-derived enterotoxigenic Escherichia coli
Svennerholm et al. Immunity to Vibrio cholerae infection
AU774649B2 (en) Vaccine preparations containing attenuated toxin
AU778223B2 (en) Oral vaccine against diarrhea
US4728639A (en) Type-specific opsonic antibodies evoked with a synthetic peptide of streptococcal M protein conjugated to polylysine without adjuvant
Boesman-Finkelstein et al. Protection in rabbits induced by the Texas Star-SR attenuated A-B+ mutant candidate live oral cholera vaccine
Carlin et al. Oral vaccines for enterotoxigenic Escherichia coli
Beachey Type-specific opsonic antibodies evoked with a synthetic peptide of streptococcal M protein conjugated to polylysine without adjuvant
Gilligan et al. Oral enteric vaccines—clinical trials
Rijpkema et al. Immunoglobulins in bile and serum of the rabbit associated with protection after Vibrio cholerae infection and vaccination
Aron et al. Humoral immune response to Salmonella typhi outer membrane proteins
Corthésy et al. Transcutaneous Immunization Using