BG60474B2 - Метод за получаване на нови 3-хидрокси-1,4-бензодиазепин-2-они - Google Patents

Метод за получаване на нови 3-хидрокси-1,4-бензодиазепин-2-они Download PDF

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Publication number
BG60474B2
BG60474B2 BG97977A BG9797793A BG60474B2 BG 60474 B2 BG60474 B2 BG 60474B2 BG 97977 A BG97977 A BG 97977A BG 9797793 A BG9797793 A BG 9797793A BG 60474 B2 BG60474 B2 BG 60474B2
Authority
BG
Bulgaria
Prior art keywords
general formula
methoxy
benzodiazepin
compounds
hydroxy
Prior art date
Application number
BG97977A
Other languages
Bulgarian (bg)
English (en)
Inventor
Ludwig Schlager
Original Assignee
Gerot Pharmazeutika Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gerot Pharmazeutika Gmbh filed Critical Gerot Pharmazeutika Gmbh
Publication of BG60474B2 publication Critical patent/BG60474B2/bg

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG97977A 1978-12-18 1993-07-21 Метод за получаване на нови 3-хидрокси-1,4-бензодиазепин-2-они BG60474B2 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT903178A AT361492B (de) 1978-12-18 1978-12-18 Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen

Publications (1)

Publication Number Publication Date
BG60474B2 true BG60474B2 (bg) 1995-04-28

Family

ID=3610590

Family Applications (1)

Application Number Title Priority Date Filing Date
BG97977A BG60474B2 (bg) 1978-12-18 1993-07-21 Метод за получаване на нови 3-хидрокси-1,4-бензодиазепин-2-они

Country Status (25)

Country Link
US (1) US4388313A (de)
JP (1) JPS5583764A (de)
AT (1) AT361492B (de)
AU (1) AU532331B2 (de)
BE (1) BE880632A (de)
BG (1) BG60474B2 (de)
CA (1) CA1113464A (de)
CH (1) CH643248A5 (de)
DE (1) DE2950235A1 (de)
DK (1) DK154973C (de)
ES (1) ES486895A0 (de)
FI (1) FI67375C (de)
FR (1) FR2444672A1 (de)
GB (1) GB2043630B (de)
GR (1) GR73901B (de)
HK (1) HK33385A (de)
IT (1) IT1193345B (de)
LU (1) LU81990A1 (de)
MY (1) MY8600020A (de)
NL (1) NL187068C (de)
NO (1) NO151859C (de)
SE (1) SE440351B (de)
SG (1) SG13585G (de)
YU (1) YU40586B (de)
ZA (1) ZA796600B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE132974T1 (de) * 1986-10-24 1996-01-15 Abbott Lab Test, indikatoren, immunogene und antikörper für benzodiazepine

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3311612A (en) * 1967-03-28 Process for preparing
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
BE621819A (de) * 1961-08-29
GB1050401A (de) * 1963-02-19 1900-01-01
NL298071A (de) * 1963-06-04
GB1052144A (de) * 1964-02-11
FR135F (de) * 1964-08-13
NO120269B (de) * 1965-11-02 1970-09-28 Hoffmann La Roche
US3464978A (en) * 1967-04-21 1969-09-02 Hoffmann La Roche 1-substituted urea alkyl 1,2-dihydro-1,4-benzodiazepines and benzodiazepin - 2-ones
CH574421A5 (en) * 1969-02-14 1976-04-15 Hoffmann La Roche Benzodiazepines
AT309436B (de) * 1970-06-23 1973-08-27 Gerot Pharmazeutika Verfahren zur Herstellung von 3-Hydroxy-1,4-benzodiazepin Derivaten oder deren Salzen
US4065451A (en) * 1971-03-30 1977-12-27 American Home Products 1,3-Dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one, substituted diamino acetate esters and their acid salts
CH573416A5 (de) * 1971-07-30 1976-03-15 Sumitomo Chemical Co
US3801568A (en) * 1972-02-07 1974-04-02 American Home Prod Optically active 1,3-dihydro-3-substituted 5-phenyl-2h-1,4-benzodiazepin-2-ones and process for their separation
JPS494226A (de) * 1972-04-27 1974-01-16

Also Published As

Publication number Publication date
FR2444672B1 (de) 1983-05-13
DK154973C (da) 1989-06-05
DE2950235A1 (de) 1980-06-26
DK154973B (da) 1989-01-16
SE7910333L (sv) 1980-06-19
FR2444672A1 (fr) 1980-07-18
NL7908919A (nl) 1980-06-20
DE2950235C2 (de) 1987-08-27
CA1113464A (en) 1981-12-01
JPS6310699B2 (de) 1988-03-08
NO151859C (no) 1985-06-19
IT1193345B (it) 1988-06-15
ATA903178A (de) 1980-08-15
NL187068B (nl) 1990-12-17
GB2043630B (en) 1983-06-15
NO793827L (no) 1980-06-19
ZA796600B (en) 1981-07-29
SG13585G (en) 1985-08-16
DK510379A (da) 1980-06-19
NO151859B (no) 1985-03-11
ES8103738A1 (es) 1980-10-01
IT7928149A0 (it) 1979-12-18
LU81990A1 (fr) 1981-07-23
AU5366479A (en) 1980-06-26
GB2043630A (en) 1980-10-08
GR73901B (de) 1984-05-18
US4388313A (en) 1983-06-14
AT361492B (de) 1981-03-10
CH643248A5 (de) 1984-05-30
SE440351B (sv) 1985-07-29
AU532331B2 (en) 1983-09-29
JPS5583764A (en) 1980-06-24
YU40586B (en) 1986-02-28
FI67375B (fi) 1984-11-30
FI67375C (fi) 1985-03-11
BE880632A (fr) 1980-06-16
NL187068C (nl) 1991-05-16
ES486895A0 (es) 1980-10-01
YU308779A (en) 1983-02-28
MY8600020A (en) 1986-12-31
HK33385A (en) 1985-05-10
FI793924A (fi) 1980-06-19

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