BG47197A3 - Метод за получаване на 3(хидроксиметил)-изохинолинови производни - Google Patents
Метод за получаване на 3(хидроксиметил)-изохинолинови производниInfo
- Publication number
- BG47197A3 BG47197A3 BG079834A BG7983487A BG47197A3 BG 47197 A3 BG47197 A3 BG 47197A3 BG 079834 A BG079834 A BG 079834A BG 7983487 A BG7983487 A BG 7983487A BG 47197 A3 BG47197 A3 BG 47197A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- hydroxymethyl
- preparation
- isoquinoline derivatives
- heart failure
- cardiotonic
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- CMGQQHGOFWZGJH-UHFFFAOYSA-N isoquinolin-3-ylmethanol Chemical class C1=CC=C2C=NC(CO)=CC2=C1 CMGQQHGOFWZGJH-UHFFFAOYSA-N 0.000 title 1
- 206010007558 Cardiac failure chronic Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 230000003177 cardiotonic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000004165 myocardium Anatomy 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU862141A HU196758B (en) | 1986-05-21 | 1986-05-21 | Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG47197A3 true BG47197A3 (bg) | 1990-05-15 |
Family
ID=10957979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG079834A BG47197A3 (bg) | 1986-05-21 | 1987-05-21 | Метод за получаване на 3(хидроксиметил)-изохинолинови производни |
Country Status (22)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8800397D0 (en) * | 1988-01-08 | 1988-02-10 | Sandoz Ltd | Improvements in/relating to organic compounds |
| GB9027055D0 (en) * | 1990-12-13 | 1991-02-06 | Sandoz Ltd | Organic compounds |
| GB9322828D0 (en) * | 1993-11-05 | 1993-12-22 | Sandoz Ltd | Organic compounds |
| PL362916A1 (en) * | 2000-08-01 | 2004-11-02 | Ono Pharmaceutical Co, Ltd. | 3,4-dihydroisoquinoline derivative compounds and drugs containing these compounds as the active ingredient |
| JP2004511465A (ja) | 2000-10-10 | 2004-04-15 | カリックス セラピューティックス インコーポレイテッド | 三環式化合物およびその使用 |
| AR035513A1 (es) * | 2000-12-23 | 2004-06-02 | Hoffmann La Roche | Derivados de tetrahidropiridina, proceso para prepararlos, composiciones farmaceuticas que los contienen, y uso de dichos compuestos en la preparacion de medicamentos |
| RU2417221C1 (ru) * | 2009-11-02 | 2011-04-27 | Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" | (1z,3z)-4-арил-4-гидрокси-1-(3,3-диалкил-3,4-дигидроизохинолин-1(2н)-илиден)-бут-3-ен-4-оны и способ их получения |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1400425A (en) * | 1971-09-22 | 1975-07-16 | Rolland Sa A | Substituted 3-hydroxymethyl-isoquinolines and derivatives |
| FR2525595A1 (fr) * | 1982-04-27 | 1983-10-28 | Pharmuka Lab | Nouveaux derives d'arene et d'heteroarenecarboxamides et leur utilisation comme medicaments |
-
1986
- 1986-05-21 HU HU862141A patent/HU196758B/hu not_active IP Right Cessation
-
1987
- 1987-05-19 CH CH1917/87A patent/CH673280A5/de not_active IP Right Cessation
- 1987-05-20 US US07/051,767 patent/US4785104A/en not_active Expired - Fee Related
- 1987-05-21 FI FI872256A patent/FI872256A7/fi not_active IP Right Cessation
- 1987-05-21 PL PL1987265811A patent/PL265811A1/xx unknown
- 1987-05-21 CS CS873691A patent/CS264293B2/cs unknown
- 1987-05-21 SE SE8702119A patent/SE8702119L/xx not_active Application Discontinuation
- 1987-05-21 FR FR8707119A patent/FR2599033A1/fr not_active Withdrawn
- 1987-05-21 BG BG079834A patent/BG47197A3/xx unknown
- 1987-05-21 NL NL8701214A patent/NL8701214A/nl not_active Application Discontinuation
- 1987-05-21 IL IL82614A patent/IL82614A0/xx unknown
- 1987-05-21 BE BE8700572A patent/BE1000719A4/fr not_active IP Right Cessation
- 1987-05-21 PT PT84924A patent/PT84924B/pt unknown
- 1987-05-21 JP JP62124993A patent/JPS6339863A/ja active Pending
- 1987-05-21 IT IT8720618A patent/IT1208046B/it active
- 1987-05-21 GB GB8712047A patent/GB2190678B/en not_active Expired - Lifetime
- 1987-05-21 DE DE19873717079 patent/DE3717079A1/de not_active Withdrawn
- 1987-05-21 DD DD87303003A patent/DD268940A5/de unknown
- 1987-05-21 DK DK258287A patent/DK258287A/da not_active Application Discontinuation
- 1987-05-21 ES ES8701497A patent/ES2005583A6/es not_active Expired
- 1987-05-21 SU SU874202630A patent/SU1551245A3/ru active
- 1987-05-21 YU YU00907/87A patent/YU90787A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI872256A0 (fi) | 1987-05-21 |
| CS369187A2 (en) | 1988-09-16 |
| DK258287A (da) | 1987-11-22 |
| SU1551245A3 (ru) | 1990-03-15 |
| PT84924A (en) | 1987-06-01 |
| IL82614A0 (en) | 1987-11-30 |
| NL8701214A (nl) | 1987-12-16 |
| GB2190678B (en) | 1990-06-20 |
| US4785104A (en) | 1988-11-15 |
| CH673280A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-02-28 |
| DK258287D0 (da) | 1987-05-21 |
| ES2005583A6 (es) | 1989-03-16 |
| PT84924B (en) | 1989-07-20 |
| DD268940A5 (de) | 1989-06-14 |
| IT1208046B (it) | 1989-06-01 |
| IT8720618A0 (it) | 1987-05-21 |
| HUT44017A (en) | 1988-01-28 |
| DE3717079A1 (de) | 1988-01-07 |
| JPS6339863A (ja) | 1988-02-20 |
| GB2190678A (en) | 1987-11-25 |
| SE8702119L (sv) | 1987-11-22 |
| CS264293B2 (en) | 1989-06-13 |
| HU196758B (en) | 1989-01-30 |
| FI872256A7 (fi) | 1987-11-22 |
| SE8702119D0 (sv) | 1987-05-21 |
| FR2599033A1 (fr) | 1987-11-27 |
| BE1000719A4 (fr) | 1989-03-21 |
| PL265811A1 (en) | 1988-07-21 |
| YU90787A (en) | 1988-08-31 |
| GB8712047D0 (en) | 1987-06-24 |
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