BG23220A3 - Метод за получаване на пеницилини - Google Patents

Метод за получаване на пеницилини

Info

Publication number
BG23220A3
BG23220A3 BG017580A BG1758071A BG23220A3 BG 23220 A3 BG23220 A3 BG 23220A3 BG 017580 A BG017580 A BG 017580A BG 1758071 A BG1758071 A BG 1758071A BG 23220 A3 BG23220 A3 BG 23220A3
Authority
BG
Bulgaria
Prior art keywords
penicillins
obtaining
obtaining penicillins
Prior art date
Application number
BG017580A
Other languages
Bulgarian (bg)
English (en)
Inventor
Hans Koenig
Wilfried Schroeck
Hans Disselnkoetter
Karl Metzger
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2025414A external-priority patent/DE2025414C3/de
Priority claimed from DE19712104580 external-priority patent/DE2104580C3/de
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG23220A3 publication Critical patent/BG23220A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • C07D233/38One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG017580A 1970-05-25 1971-05-13 Метод за получаване на пеницилини BG23220A3 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2025414A DE2025414C3 (de) 1970-05-25 1970-05-25 Cyclische Acylureidophenylacetamidopenicillansäuren
DE19712104580 DE2104580C3 (de) 1971-02-01 1971-02-01 Acylureidopenicilline

Publications (1)

Publication Number Publication Date
BG23220A3 true BG23220A3 (bg) 1977-07-12

Family

ID=25759178

Family Applications (1)

Application Number Title Priority Date Filing Date
BG017580A BG23220A3 (bg) 1970-05-25 1971-05-13 Метод за получаване на пеницилини

Country Status (28)

Country Link
JP (1) JPS5538357B1 (hu)
AR (2) AR195267A1 (hu)
AT (1) AT307617B (hu)
BE (1) BE767647A (hu)
BG (1) BG23220A3 (hu)
CA (1) CA943128A (hu)
CH (1) CH562249A5 (hu)
CS (1) CS171230B2 (hu)
CY (1) CY829A (hu)
DD (1) DD91497B3 (hu)
DK (1) DK133679C (hu)
EG (1) EG10856A (hu)
ES (4) ES391532A1 (hu)
FI (1) FI54484C (hu)
FR (1) FR2100681B1 (hu)
GB (1) GB1301961A (hu)
HU (1) HU162205B (hu)
IE (1) IE35311B1 (hu)
IL (1) IL36905A (hu)
KE (1) KE2592A (hu)
LU (1) LU63203A1 (hu)
NL (1) NL172660C (hu)
NO (1) NO141164C (hu)
PH (1) PH14794A (hu)
RO (2) RO59157A (hu)
SE (1) SE395896B (hu)
SU (1) SU472507A3 (hu)
YU (1) YU130271A (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039673A (en) 1973-10-30 1977-08-02 Bayer Aktiengesellschaft Penicillins and cephalosporins and their production
DE2354219A1 (de) * 1973-10-30 1975-05-07 Bayer Ag Beta-lactam-antibiotica, ein verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1486349A (en) * 1974-11-28 1977-09-21 Bayer Ag Beta-lactam antibiotics process for their preparation and their use as medicaments
DE2658906A1 (de) * 1976-12-24 1978-07-06 Bayer Ag Beta-lactam-antibiotika, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1584400A (en) * 1976-12-24 1981-02-11 Bayer Ag (2-oxo-imidazoliden-1-yl(carbonylamino)-acetamido-cephalosporins and penicillins
US4229348A (en) * 1978-05-26 1980-10-21 Chugai Seiyaku Kabushiki Kaisha Penicillanic acid derivatives
JPS5732289A (en) 1980-08-05 1982-02-20 Chugai Pharmaceut Co Ltd Alpha-substituted ureidobenzylpenicillin

Also Published As

Publication number Publication date
IL36905A (en) 1975-11-25
CS171230B2 (hu) 1976-10-29
DK133679B (da) 1976-06-28
FR2100681B1 (hu) 1974-10-18
DD91497A5 (de) 1972-07-20
ES403124A1 (es) 1976-01-01
DK133679C (da) 1976-11-15
LU63203A1 (hu) 1971-09-01
AR195946A1 (es) 1973-11-15
IL36905A0 (en) 1971-07-28
KE2592A (en) 1976-01-09
NL172660C (nl) 1983-10-03
GB1301961A (hu) 1973-01-04
NL7107175A (hu) 1971-11-29
IE35311L (en) 1971-11-25
NO141164C (no) 1980-01-23
SU472507A3 (ru) 1975-05-30
RO59157A (hu) 1976-04-15
FI54484B (fi) 1978-08-31
CA943128A (en) 1974-03-05
EG10856A (en) 1977-05-31
DD91497B3 (de) 1988-01-27
FR2100681A1 (hu) 1972-03-24
AT307617B (de) 1973-05-25
ES391532A1 (es) 1974-10-01
NL172660B (nl) 1983-05-02
ES403125A1 (es) 1975-12-16
SE395896B (sv) 1977-08-29
RO62689A (fr) 1978-05-15
CH562249A5 (hu) 1975-05-30
YU130271A (en) 1982-02-25
PH14794A (en) 1981-12-09
JPS5538357B1 (hu) 1980-10-03
HU162205B (hu) 1973-01-29
BE767647A (hu) 1971-11-25
FI54484C (fi) 1978-12-11
IE35311B1 (en) 1976-01-07
ES403126A1 (es) 1975-05-01
NO141164B (no) 1979-10-15
CY829A (en) 1976-03-19
AR195267A1 (es) 1973-09-28

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