BG107810A - Използване на селективни допамин-d4-рецепторни агонисти за лечение на сексуална дисфункция - Google Patents
Използване на селективни допамин-d4-рецепторни агонисти за лечение на сексуална дисфункция Download PDFInfo
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- BG107810A BG107810A BG107810A BG10781003A BG107810A BG 107810 A BG107810 A BG 107810A BG 107810 A BG107810 A BG 107810A BG 10781003 A BG10781003 A BG 10781003A BG 107810 A BG107810 A BG 107810A
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- dopamine
- receptor
- treatment
- pharmaceutically acceptable
- receptor agonist
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- 230000003767 neural control Effects 0.000 description 1
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- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
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- 239000005022 packaging material Substances 0.000 description 1
- 230000001734 parasympathetic effect Effects 0.000 description 1
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- 238000001050 pharmacotherapy Methods 0.000 description 1
- 229960003742 phenol Drugs 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000002590 phosphodiesterase V inhibitor Substances 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000006461 physiological response Effects 0.000 description 1
- 229940075930 picrate Drugs 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-M picrate anion Chemical compound [O-]C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-M 0.000 description 1
- 230000001817 pituitary effect Effects 0.000 description 1
- 229950010765 pivalate Drugs 0.000 description 1
- IUGYQRQAERSCNH-UHFFFAOYSA-N pivalic acid Chemical compound CC(C)(C)C(O)=O IUGYQRQAERSCNH-UHFFFAOYSA-N 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
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- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 230000004648 relaxation of smooth muscle Effects 0.000 description 1
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- 239000004248 saffron Substances 0.000 description 1
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- 230000001568 sexual effect Effects 0.000 description 1
- 150000004760 silicates Chemical class 0.000 description 1
- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 description 1
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- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000008247 solid mixture Substances 0.000 description 1
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- 235000012424 soybean oil Nutrition 0.000 description 1
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- 239000006190 sub-lingual tablet Substances 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
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- 238000007910 systemic administration Methods 0.000 description 1
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- 230000000542 thalamic effect Effects 0.000 description 1
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- 230000004797 therapeutic response Effects 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
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- 239000012588 trypsin Substances 0.000 description 1
- ZDPHROOEEOARMN-UHFFFAOYSA-N undecanoic acid Chemical compound CCCCCCCCCCC(O)=O ZDPHROOEEOARMN-UHFFFAOYSA-N 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
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- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 210000001030 ventral striatum Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
- 235000014692 zinc oxide Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71831100A | 2000-11-22 | 2000-11-22 | |
| US09/985,974 US20020103105A1 (en) | 2000-11-22 | 2001-11-07 | Use of selective dopamine D4 receptor agonists for treating sexual dysfunction |
| PCT/US2001/043139 WO2002041894A2 (en) | 2000-11-22 | 2001-11-21 | Selective dopamine d4 receptor agonists for treating sexual dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG107810A true BG107810A (bg) | 2004-02-27 |
Family
ID=27109879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG107810A BG107810A (bg) | 2000-11-22 | 2003-05-13 | Използване на селективни допамин-d4-рецепторни агонисти за лечение на сексуална дисфункция |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1345608B1 (es) |
| JP (1) | JP2004534725A (es) |
| KR (1) | KR20030051857A (es) |
| CN (1) | CN1531434A (es) |
| AR (1) | AR035600A1 (es) |
| AT (1) | ATE358483T1 (es) |
| AU (2) | AU2689502A (es) |
| BG (1) | BG107810A (es) |
| BR (1) | BR0110450A (es) |
| CA (1) | CA2429383A1 (es) |
| CZ (1) | CZ20031458A3 (es) |
| DE (1) | DE60127712T2 (es) |
| ES (1) | ES2284727T3 (es) |
| HK (1) | HK1059884A1 (es) |
| HU (1) | HUP0402358A3 (es) |
| IL (1) | IL155094A0 (es) |
| MX (1) | MXPA03004547A (es) |
| NO (1) | NO20032304L (es) |
| NZ (1) | NZ525086A (es) |
| PE (1) | PE20020557A1 (es) |
| PL (1) | PL365890A1 (es) |
| SK (1) | SK7242003A3 (es) |
| TW (1) | TWI293254B (es) |
| UY (1) | UY27031A1 (es) |
| WO (1) | WO2002041894A2 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| EP1509213A2 (en) * | 2002-05-23 | 2005-03-02 | Abbott Laboratories | Acetamides and benzamides that are useful in treating sexual dysfunction |
| PL1912650T3 (pl) | 2005-08-03 | 2018-01-31 | Sprout Pharmaceuticals Inc | Zastosowanie flibanseryny w leczeniu otyłości |
| CA2626134C (en) | 2005-10-29 | 2013-12-24 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| JP2009541443A (ja) | 2006-06-30 | 2009-11-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 尿失禁及び関連疾患の治療のためのフリバンセリン |
| JP5793828B2 (ja) | 2006-08-14 | 2015-10-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | フリバンセリンの製剤及びその製造方法 |
| EP2056797A2 (en) | 2006-08-25 | 2009-05-13 | Boehringer Ingelheim International GmbH | Controlled release system and method for manufacturing the same |
| CL2008002693A1 (es) | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
| CA2832822A1 (en) * | 2011-04-10 | 2012-10-18 | Atir Holding S.A. | Heterocyclic compounds and uses thereof in the treatment of sexual disorders |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69530988T2 (de) * | 1994-08-05 | 2003-12-04 | Pfizer | Benzimidazolderivate mit dopaminerger wirkung |
| US5945117A (en) * | 1998-01-30 | 1999-08-31 | Pentech Pharmaceuticals, Inc. | Treatment of female sexual dysfunction |
| EP0982030A3 (en) * | 1998-08-17 | 2000-05-10 | Pfizer Products Inc. | 2,7-substituted octahydro-pyrrolo 1,2-a]pyrazine derivatives as 5ht 1a ligands |
| US6291471B1 (en) * | 1998-12-17 | 2001-09-18 | Abb Holdings, Inc. | Use of apomorphine for the treatment of organic erectile dysfunction in males |
-
2001
- 2001-11-21 WO PCT/US2001/043139 patent/WO2002041894A2/en active IP Right Grant
- 2001-11-21 AR ARP010105435A patent/AR035600A1/es unknown
- 2001-11-21 PE PE2001001164A patent/PE20020557A1/es not_active Application Discontinuation
- 2001-11-21 NZ NZ525086A patent/NZ525086A/en unknown
- 2001-11-21 JP JP2002544072A patent/JP2004534725A/ja not_active Withdrawn
- 2001-11-21 IL IL15509401A patent/IL155094A0/xx unknown
- 2001-11-21 EP EP01995843A patent/EP1345608B1/en not_active Expired - Lifetime
- 2001-11-21 AT AT01995843T patent/ATE358483T1/de not_active IP Right Cessation
- 2001-11-21 CZ CZ20031458A patent/CZ20031458A3/cs unknown
- 2001-11-21 SK SK724-2003A patent/SK7242003A3/sk not_active Application Discontinuation
- 2001-11-21 HU HU0402358A patent/HUP0402358A3/hu unknown
- 2001-11-21 CN CNA01819205XA patent/CN1531434A/zh active Pending
- 2001-11-21 CA CA002429383A patent/CA2429383A1/en not_active Abandoned
- 2001-11-21 PL PL01365890A patent/PL365890A1/xx not_active Application Discontinuation
- 2001-11-21 UY UY27031A patent/UY27031A1/es not_active Application Discontinuation
- 2001-11-21 AU AU2689502A patent/AU2689502A/xx active Pending
- 2001-11-21 BR BR0110450-0A patent/BR0110450A/pt not_active Application Discontinuation
- 2001-11-21 AU AU2002226895A patent/AU2002226895B2/en not_active Ceased
- 2001-11-21 KR KR10-2003-7006855A patent/KR20030051857A/ko not_active Application Discontinuation
- 2001-11-21 DE DE60127712T patent/DE60127712T2/de not_active Expired - Lifetime
- 2001-11-21 MX MXPA03004547A patent/MXPA03004547A/es active IP Right Grant
- 2001-11-21 ES ES01995843T patent/ES2284727T3/es not_active Expired - Lifetime
- 2001-11-22 TW TW090128952A patent/TWI293254B/zh active
-
2003
- 2003-05-13 BG BG107810A patent/BG107810A/bg unknown
- 2003-05-21 NO NO20032304A patent/NO20032304L/no not_active Application Discontinuation
-
2004
- 2004-02-24 HK HK04101320A patent/HK1059884A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1531434A (zh) | 2004-09-22 |
| AU2002226895B2 (en) | 2006-10-12 |
| MXPA03004547A (es) | 2004-03-26 |
| ATE358483T1 (de) | 2007-04-15 |
| DE60127712T2 (de) | 2007-12-27 |
| CA2429383A1 (en) | 2002-05-30 |
| EP1345608A2 (en) | 2003-09-24 |
| DE60127712D1 (de) | 2007-05-16 |
| KR20030051857A (ko) | 2003-06-25 |
| PL365890A1 (en) | 2005-01-10 |
| PE20020557A1 (es) | 2002-06-25 |
| TWI293254B (en) | 2008-02-11 |
| HK1059884A1 (en) | 2004-07-23 |
| UY27031A1 (es) | 2002-07-31 |
| AR035600A1 (es) | 2004-06-16 |
| SK7242003A3 (en) | 2004-01-08 |
| IL155094A0 (en) | 2003-10-31 |
| NZ525086A (en) | 2006-07-28 |
| HUP0402358A3 (en) | 2009-08-28 |
| WO2002041894A2 (en) | 2002-05-30 |
| CZ20031458A3 (cs) | 2004-02-18 |
| JP2004534725A (ja) | 2004-11-18 |
| EP1345608B1 (en) | 2007-04-04 |
| AU2689502A (en) | 2002-06-03 |
| NO20032304L (no) | 2003-07-15 |
| ES2284727T3 (es) | 2007-11-16 |
| BR0110450A (pt) | 2005-02-09 |
| WO2002041894A3 (en) | 2002-10-17 |
| NO20032304D0 (no) | 2003-05-21 |
| HUP0402358A2 (hu) | 2005-03-29 |
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