BG105689A - Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia - Google Patents

Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia

Info

Publication number
BG105689A
BG105689A BG105689A BG10568901A BG105689A BG 105689 A BG105689 A BG 105689A BG 105689 A BG105689 A BG 105689A BG 10568901 A BG10568901 A BG 10568901A BG 105689 A BG105689 A BG 105689A
Authority
BG
Bulgaria
Prior art keywords
utilization
preventing
pyrimidine derivatives
treating cerebral
cerebral ischaemia
Prior art date
Application number
BG105689A
Other languages
Bulgarian (bg)
English (en)
Inventor
Gerd Steiner
Kurt SCHNELLHAAS
Wilfried Lubisch
Uta Holzenkamp
Dorothea Starck
Monika Knopp
Laszlo Szabo
Franz Emling
Francisco Garcia-Ladona
Hans-Peter Hofmann
Liliane Unger
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of BG105689A publication Critical patent/BG105689A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG105689A 1999-01-11 2001-07-10 Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia BG105689A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19900545A DE19900545A1 (de) 1999-01-11 1999-01-11 Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie
PCT/EP1999/010369 WO2000041695A1 (de) 1999-01-11 1999-12-24 Verwendung von pyrimidinderivaten zur prophylaxe und therapie der zerebralen ischämie

Publications (1)

Publication Number Publication Date
BG105689A true BG105689A (en) 2002-02-28

Family

ID=7893836

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105689A BG105689A (en) 1999-01-11 2001-07-10 Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia

Country Status (24)

Country Link
US (1) US6387912B1 (zh)
EP (1) EP1140096A1 (zh)
JP (1) JP2002534465A (zh)
KR (1) KR20010101442A (zh)
CN (1) CN1334732A (zh)
AU (1) AU2433800A (zh)
BG (1) BG105689A (zh)
BR (1) BR9916887A (zh)
CA (1) CA2359253A1 (zh)
CZ (2) CZ20012484A3 (zh)
DE (1) DE19900545A1 (zh)
HK (1) HK1042649A1 (zh)
HU (1) HUP0201149A3 (zh)
ID (1) ID30022A (zh)
IL (1) IL144146A0 (zh)
MX (1) MXPA01006967A (zh)
MY (1) MY133107A (zh)
NO (1) NO20013409L (zh)
NZ (1) NZ512767A (zh)
PL (1) PL348920A1 (zh)
SK (1) SK9692001A3 (zh)
TR (1) TR200102008T2 (zh)
WO (1) WO2000041695A1 (zh)
ZA (1) ZA200105475B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19900673A1 (de) 1999-01-11 2000-07-13 Basf Ag Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen
US6988199B2 (en) * 2000-07-07 2006-01-17 Message Secure Secure and reliable document delivery
JP4548882B2 (ja) * 1999-11-30 2010-09-22 興和創薬株式会社 ４，５，６，７−テトラヒドロチエノ〔２，３−ｃ〕ピリジン化合物
DE10031389A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10031390A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
CA2685753A1 (en) * 2007-05-09 2008-11-20 Neuromed Pharmaceuticals Ltd. Bicyclic pyrimidine derivatives as calcium channel blockers
EP2471791B1 (en) * 2009-08-26 2014-11-12 Takeda Pharmaceutical Company Limited Fused heterocyclic ring derivative and use thereof
US11753413B2 (en) 2020-06-19 2023-09-12 Incyte Corporation Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors
US11691971B2 (en) 2020-06-19 2023-07-04 Incyte Corporation Naphthyridinone compounds as JAK2 V617F inhibitors
TW202216713A (zh) 2020-07-02 2022-05-01 美商英塞特公司 作為ｊａｋ２ ｖ６１７ｆ抑制劑之三環脲化合物
US11767323B2 (en) 2020-07-02 2023-09-26 Incyte Corporation Tricyclic pyridone compounds as JAK2 V617F inhibitors
WO2022046989A1 (en) 2020-08-27 2022-03-03 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors
WO2022140231A1 (en) 2020-12-21 2022-06-30 Incyte Corporation Deazaguaine compounds as jak2 v617f inhibitors
US11958861B2 (en) 2021-02-25 2024-04-16 Incyte Corporation Spirocyclic lactams as JAK2 V617F inhibitors
TW202337453A (zh) 2022-03-17 2023-10-01 美商英塞特公司 作為ｊａｋ２ ｖ６１７ｆ抑制劑之三環脲化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670560A (en) * 1986-04-28 1987-06-02 Ortho Pharmaceutical Corporation Thienopyrimidine-2,4-dione derivatives and intermediates thereof
DE19636769A1 (de) 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724980A1 (de) 1997-06-13 1998-12-17 Basf Ag 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724979A1 (de) 1997-06-13 1998-12-17 Basf Ag 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
EP1140096A1 (de) 2001-10-10
ID30022A (id) 2001-11-01
BR9916887A (pt) 2001-11-20
CZ20012485A3 (cs) 2002-04-17
KR20010101442A (ko) 2001-11-14
WO2000041695A1 (de) 2000-07-20
MXPA01006967A (es) 2002-04-10
HUP0201149A3 (en) 2003-07-28
IL144146A0 (en) 2002-05-23
AU2433800A (en) 2000-08-01
DE19900545A1 (de) 2000-07-13
JP2002534465A (ja) 2002-10-15
HUP0201149A2 (hu) 2002-07-29
ZA200105475B (en) 2002-10-03
CA2359253A1 (en) 2000-07-20
PL348920A1 (en) 2002-06-17
CZ20012484A3 (cs) 2002-05-15
MY133107A (en) 2007-10-31
NZ512767A (en) 2003-05-30
US6387912B1 (en) 2002-05-14
SK9692001A3 (en) 2002-05-09
CN1334732A (zh) 2002-02-06
HK1042649A1 (zh) 2002-08-23
NO20013409L (no) 2001-08-30
NO20013409D0 (no) 2001-07-10
TR200102008T2 (tr) 2001-12-21

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