NO20013409L - Anvendelse av pyrimidin-derivater for forhindring og behandling av cerebral ischemi - Google Patents

Anvendelse av pyrimidin-derivater for forhindring og behandling av cerebral ischemi

Info

Publication number
NO20013409L
NO20013409L NO20013409A NO20013409A NO20013409L NO 20013409 L NO20013409 L NO 20013409L NO 20013409 A NO20013409 A NO 20013409A NO 20013409 A NO20013409 A NO 20013409A NO 20013409 L NO20013409 L NO 20013409L
Authority
NO
Norway
Prior art keywords
prevention
treatment
cerebral ischemia
pyrimidine derivatives
substituents
Prior art date
Application number
NO20013409A
Other languages
English (en)
Other versions
NO20013409D0 (no
Inventor
Gerd Steinler
Kurt Schellhaas
Wilfried Lubisch
Uta Holzenkamp
Dorothea Starck
Monika Knopp
Laszlo Szabo
Franz Emling
Francisco-Javier Garcia-Ladona
Hans Peter Hofmann
Liliane Unger
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO20013409D0 publication Critical patent/NO20013409D0/no
Publication of NO20013409L publication Critical patent/NO20013409L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Anvendelse av pyrimidinderivater med formel l (CH)a¿X Z-----l Y (D hvor substituentene er som definert i beskrivelsen, og deres fysiologisk tolererte salter for å produsere medikamenter for forebygging og behandling av cerebral ischemi og slag.
NO20013409A 1999-01-11 2001-07-10 Anvendelse av pyrimidin-derivater for forhindring og behandling av cerebral ischemi NO20013409L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19900545A DE19900545A1 (de) 1999-01-11 1999-01-11 Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie
PCT/EP1999/010369 WO2000041695A1 (de) 1999-01-11 1999-12-24 Verwendung von pyrimidinderivaten zur prophylaxe und therapie der zerebralen ischämie

Publications (2)

Publication Number Publication Date
NO20013409D0 NO20013409D0 (no) 2001-07-10
NO20013409L true NO20013409L (no) 2001-08-30

Family

ID=7893836

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013409A NO20013409L (no) 1999-01-11 2001-07-10 Anvendelse av pyrimidin-derivater for forhindring og behandling av cerebral ischemi

Country Status (24)

Country Link
US (1) US6387912B1 (no)
EP (1) EP1140096A1 (no)
JP (1) JP2002534465A (no)
KR (1) KR20010101442A (no)
CN (1) CN1334732A (no)
AU (1) AU2433800A (no)
BG (1) BG105689A (no)
BR (1) BR9916887A (no)
CA (1) CA2359253A1 (no)
CZ (2) CZ20012484A3 (no)
DE (1) DE19900545A1 (no)
HK (1) HK1042649A1 (no)
HU (1) HUP0201149A3 (no)
ID (1) ID30022A (no)
IL (1) IL144146A0 (no)
MX (1) MXPA01006967A (no)
MY (1) MY133107A (no)
NO (1) NO20013409L (no)
NZ (1) NZ512767A (no)
PL (1) PL348920A1 (no)
SK (1) SK9692001A3 (no)
TR (1) TR200102008T2 (no)
WO (1) WO2000041695A1 (no)
ZA (1) ZA200105475B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19900673A1 (de) 1999-01-11 2000-07-13 Basf Ag Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen
US6988199B2 (en) * 2000-07-07 2006-01-17 Message Secure Secure and reliable document delivery
JP4548882B2 (ja) * 1999-11-30 2010-09-22 興和創薬株式会社 ４，５，６，７−テトラヒドロチエノ〔２，３−ｃ〕ピリジン化合物
DE10031390A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10031389A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
WO2008138126A1 (en) * 2007-05-09 2008-11-20 Neuromed Pharmaceuticals Ltd. Bicyclic pyrimidine derivatives as calcium channel blockers
WO2011024873A1 (ja) * 2009-08-26 2011-03-03 武田薬品工業株式会社 縮合複素環誘導体およびその用途
US11753413B2 (en) 2020-06-19 2023-09-12 Incyte Corporation Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors
WO2021257857A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Naphthyridinone compounds as jak2 v617f inhibitors
AU2021300429A1 (en) 2020-07-02 2023-02-16 Incyte Corporation Tricyclic urea compounds as JAK2 V617F inhibitors
WO2022006456A1 (en) 2020-07-02 2022-01-06 Incyte Corporation Tricyclic pyridone compounds as jak2 v617f inhibitors
US11661422B2 (en) 2020-08-27 2023-05-30 Incyte Corporation Tricyclic urea compounds as JAK2 V617F inhibitors
US11919908B2 (en) 2020-12-21 2024-03-05 Incyte Corporation Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors
TW202302589A (zh) 2021-02-25 2023-01-16 美商英塞特公司 作為ｊａｋ２ ｖ６１７ｆ抑制劑之螺環內醯胺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670560A (en) 1986-04-28 1987-06-02 Ortho Pharmaceutical Corporation Thienopyrimidine-2,4-dione derivatives and intermediates thereof
DE19636769A1 (de) 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724980A1 (de) 1997-06-13 1998-12-17 Basf Ag 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724979A1 (de) 1997-06-13 1998-12-17 Basf Ag 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
IL144146A0 (en) 2002-05-23
KR20010101442A (ko) 2001-11-14
HK1042649A1 (zh) 2002-08-23
WO2000041695A1 (de) 2000-07-20
NZ512767A (en) 2003-05-30
HUP0201149A2 (hu) 2002-07-29
MXPA01006967A (es) 2002-04-10
CZ20012484A3 (cs) 2002-05-15
AU2433800A (en) 2000-08-01
CZ20012485A3 (cs) 2002-04-17
CA2359253A1 (en) 2000-07-20
SK9692001A3 (en) 2002-05-09
HUP0201149A3 (en) 2003-07-28
JP2002534465A (ja) 2002-10-15
DE19900545A1 (de) 2000-07-13
PL348920A1 (en) 2002-06-17
US6387912B1 (en) 2002-05-14
BG105689A (en) 2002-02-28
EP1140096A1 (de) 2001-10-10
TR200102008T2 (tr) 2001-12-21
BR9916887A (pt) 2001-11-20
CN1334732A (zh) 2002-02-06
ID30022A (id) 2001-11-01
MY133107A (en) 2007-10-31
ZA200105475B (en) 2002-10-03
NO20013409D0 (no) 2001-07-10

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