BG105136A - 4,5,6 and 7-indole and indoline derivatives, their preparation and use - Google Patents
4,5,6 and 7-indole and indoline derivatives, their preparation and useInfo
- Publication number
- BG105136A BG105136A BG105136A BG10513601A BG105136A BG 105136 A BG105136 A BG 105136A BG 105136 A BG105136 A BG 105136A BG 10513601 A BG10513601 A BG 10513601A BG 105136 A BG105136 A BG 105136A
- Authority
- BG
- Bulgaria
- Prior art keywords
- indole
- preparation
- indoline derivatives
- derivatives
- formulae
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK82098 | 1998-06-19 | ||
US9282398P | 1998-07-14 | 1998-07-14 | |
PCT/DK1999/000326 WO1999067237A1 (en) | 1998-06-19 | 1999-06-14 | 4,5,6 and 7-indole and indoline derivatives, their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
BG105136A true BG105136A (en) | 2001-09-28 |
Family
ID=26064717
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG105136A BG105136A (en) | 1998-06-19 | 2001-01-10 | 4,5,6 and 7-indole and indoline derivatives, their preparation and use |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1089997A1 (no) |
JP (1) | JP2003521443A (no) |
AU (1) | AU765317C (no) |
BG (1) | BG105136A (no) |
CA (1) | CA2335711A1 (no) |
HR (1) | HRP20000847A2 (no) |
HU (1) | HUP0101475A3 (no) |
NO (1) | NO20006460L (no) |
NZ (1) | NZ508506A (no) |
WO (1) | WO1999067237A1 (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA9711376B (en) * | 1996-12-20 | 1998-07-21 | Lundbeck & Co As H | Indole or dihydroindole derivatives |
GB9912413D0 (en) | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
GB9912417D0 (en) | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
IL148218A0 (en) * | 1999-08-23 | 2002-09-12 | Solvay Pharm Bv | New phenylpiperazines |
AR032712A1 (es) | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen |
AR032711A1 (es) * | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Derivados de fenilpiperazina, un metodo para la preparacion de los mismos y una composicion farmaceutica que los contiene |
PL211057B1 (pl) * | 2002-05-13 | 2012-04-30 | Hoffmann La Roche | Pochodne benzoksazyny, sposób ich wytwarzania, środek farmaceutyczny i zastosowanie pochodnych benzoksazyny |
TW200409777A (en) * | 2002-08-12 | 2004-06-16 | Janssen Pharmaceutica Nv | C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants |
WO2004018483A1 (en) | 2002-08-15 | 2004-03-04 | Janssen Pharmaceutica N.V. | Fused heterocyclic isoxazoline derivatives and their use as anti-depressants |
AU2003257407A1 (en) * | 2002-08-29 | 2004-03-19 | H. Lundbeck A/S | S-(+)-3-{1-(2-(2,3-dihydro-1h-indol-3-yl)ethyl)-3,6-dihydro-2h-pyridin-4-yl}-6-chloro-1h-indole and acid addition salts thereof |
GB0227240D0 (en) * | 2002-11-21 | 2002-12-31 | Glaxo Group Ltd | Compounds |
US7276603B2 (en) | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
US7235569B2 (en) | 2003-05-02 | 2007-06-26 | Wyeth | Piperidinyl indole and tetrohydropyridinyl indole derivatives and method of their use |
CA2587357A1 (en) * | 2004-12-08 | 2006-06-15 | Solvay Pharmaceuticals B.V. | Phenylpiperazine derivatives with a combination of partial dopamine-d2 receptor agonism and serotonin reuptake inhibition |
US7807671B2 (en) | 2006-04-25 | 2010-10-05 | Bristol-Myers Squibb Company | Diketo-piperazine and piperidine derivatives as antiviral agents |
JP2010509259A (ja) | 2006-11-09 | 2010-03-25 | エフ.ホフマン−ラ ロシュ アーゲー | インドール及びベンゾフラン2−カルボキサミド誘導体 |
AU2009225025A1 (en) * | 2008-03-14 | 2009-09-17 | Merck Patent Gmbh | Azaindole compounds for treatment of central nervous system disorders |
CN103420989B (zh) * | 2012-05-15 | 2016-03-23 | 华中科技大学 | 苯并二噁烷类衍生物及其应用 |
EP3027607B1 (en) | 2013-07-29 | 2020-08-26 | Sunshine Lake Pharma Co., Ltd. | Substituted heteroaryl compounds and methods of use thereof |
CN105732591B (zh) * | 2014-12-31 | 2019-10-25 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
WO2017012579A1 (zh) * | 2015-07-23 | 2017-01-26 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9305641D0 (en) * | 1993-03-18 | 1993-05-05 | Merck Sharp & Dohme | Therapeutic agents |
DE4414113A1 (de) * | 1994-04-22 | 1995-10-26 | Merck Patent Gmbh | 3-Indolylpiperidine |
ZA9711376B (en) * | 1996-12-20 | 1998-07-21 | Lundbeck & Co As H | Indole or dihydroindole derivatives |
-
1999
- 1999-06-14 NZ NZ508506A patent/NZ508506A/en unknown
- 1999-06-14 JP JP2000555890A patent/JP2003521443A/ja not_active Withdrawn
- 1999-06-14 WO PCT/DK1999/000326 patent/WO1999067237A1/en not_active Application Discontinuation
- 1999-06-14 AU AU43592/99A patent/AU765317C/en not_active Ceased
- 1999-06-14 EP EP99926281A patent/EP1089997A1/en not_active Withdrawn
- 1999-06-14 HU HU0101475A patent/HUP0101475A3/hu unknown
- 1999-06-14 CA CA002335711A patent/CA2335711A1/en not_active Abandoned
-
2000
- 2000-12-11 HR HR20000847A patent/HRP20000847A2/hr not_active Application Discontinuation
- 2000-12-18 NO NO20006460A patent/NO20006460L/no not_active Application Discontinuation
-
2001
- 2001-01-10 BG BG105136A patent/BG105136A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JP2003521443A (ja) | 2003-07-15 |
AU765317B2 (en) | 2003-09-18 |
EP1089997A1 (en) | 2001-04-11 |
HUP0101475A3 (en) | 2003-01-28 |
NO20006460D0 (no) | 2000-12-18 |
HUP0101475A2 (hu) | 2001-10-28 |
NO20006460L (no) | 2001-02-19 |
WO1999067237A1 (en) | 1999-12-29 |
NZ508506A (en) | 2004-01-30 |
CA2335711A1 (en) | 1999-12-29 |
HRP20000847A2 (en) | 2001-12-31 |
AU4359299A (en) | 2000-01-10 |
AU765317C (en) | 2004-05-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BG105136A (en) | 4,5,6 and 7-indole and indoline derivatives, their preparation and use | |
DE60004066D1 (de) | Benzofurylpiperazine: 5-ht2c serotoninrezeptor agonisten | |
AR023777A1 (es) | Nuevos compuestos | |
TR200101398T2 (tr) | Pirolidin türevleri-CCR-3 reseptörü antagonistleri. | |
PL327735A1 (en) | Novel substituted derivatives of imidazole | |
MY134568A (en) | Cb2 receptor agonists | |
BG104148A (en) | Indole and 2,3-dihydroindole derivatives, their preparation and use | |
PT935465E (pt) | Compostos novos de imidazole substituido | |
MX9702070A (es) | Nuevos inhibidores de resorcion osea y antagonistas de receptor de vitronectina. | |
AU1529402A (en) | Piperazinylpyrazines compounds as antagonists of serotonin 5-ht2 receptor | |
DK1000035T3 (da) | Substituerede 6-phenylphenanthridiner | |
ES2189968T3 (es) | Amidinofenil-pirrolidinas,-pirrolinas,e -isoxazolidinas y derivadOS DE LOS MISMOS. | |
SE9702773D0 (sv) | Novel compounds | |
DE59914814D1 (de) | Heterozyklische substituierte amide, deren herstellung und anwendung | |
SE9802208D0 (sv) | Novel compounds | |
BG106930A (en) | Substituted phenyl-piperazine derivatives, their preparation and use | |
EP1244452A4 (en) | UROTENSIN II RECEPTOR ANTAGONISTS | |
TR199902848T2 (xx) | Ergolin t�revleri ve bunlar�n somatostatin resept�r antagonist olarak kullan�mlar� | |
PT920426E (pt) | Novos derivados de tiazole com efeito inibidor de fosfodiesterase | |
BG105710A (en) | 5ht1 antagonists for antidepressant therapy | |
IS6426A (is) | Píperasínómetýlbensamíð sem delta-ópíóíðviðtakagerandefni | |
ATE235480T1 (de) | Chalcon coumarine | |
MY120550A (en) | Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, processes for preparing them and their use as pharmaceutical compositions. | |
ATE259813T1 (de) | Triazolopyrimidinderivate | |
ATE219481T1 (de) | 1,7,7-trimethyl-bicyclo(2.2.1)heptane derivative |