HUP0101475A3 - 4,5,6 and 7-indole and indoline derivatives, their preparation and use - Google Patents

4,5,6 and 7-indole and indoline derivatives, their preparation and use

Info

Publication number
HUP0101475A3
HUP0101475A3 HU0101475A HUP0101475A HUP0101475A3 HU P0101475 A3 HUP0101475 A3 HU P0101475A3 HU 0101475 A HU0101475 A HU 0101475A HU P0101475 A HUP0101475 A HU P0101475A HU P0101475 A3 HUP0101475 A3 HU P0101475A3
Authority
HU
Hungary
Prior art keywords
indole
preparation
indoline derivatives
indoline
derivatives
Prior art date
Application number
HU0101475A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of HUP0101475A2 publication Critical patent/HUP0101475A2/hu
Publication of HUP0101475A3 publication Critical patent/HUP0101475A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
HU0101475A 1998-06-19 1999-06-14 4,5,6 and 7-indole and indoline derivatives, their preparation and use HUP0101475A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK82098 1998-06-19
US9282398P 1998-07-14 1998-07-14
PCT/DK1999/000326 WO1999067237A1 (en) 1998-06-19 1999-06-14 4,5,6 and 7-indole and indoline derivatives, their preparation and use

Publications (2)

Publication Number Publication Date
HUP0101475A2 HUP0101475A2 (hu) 2001-10-28
HUP0101475A3 true HUP0101475A3 (en) 2003-01-28

Family

ID=26064717

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101475A HUP0101475A3 (en) 1998-06-19 1999-06-14 4,5,6 and 7-indole and indoline derivatives, their preparation and use

Country Status (10)

Country Link
EP (1) EP1089997A1 (no)
JP (1) JP2003521443A (no)
AU (1) AU765317C (no)
BG (1) BG105136A (no)
CA (1) CA2335711A1 (no)
HR (1) HRP20000847A2 (no)
HU (1) HUP0101475A3 (no)
NO (1) NO20006460L (no)
NZ (1) NZ508506A (no)
WO (1) WO1999067237A1 (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9711376B (en) * 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
GB9912417D0 (en) 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
GB9912413D0 (en) * 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
SI1212320T1 (en) * 1999-08-23 2005-10-31 Solvay Pharmaceuticals B.V. Phenylpiperazines as serotonin reuptake inhibitors
AR032712A1 (es) 2001-02-21 2003-11-19 Solvay Pharm Bv Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen
AR032711A1 (es) * 2001-02-21 2003-11-19 Solvay Pharm Bv Derivados de fenilpiperazina, un metodo para la preparacion de los mismos y una composicion farmaceutica que los contiene
ATE316523T1 (de) * 2002-05-13 2006-02-15 Hoffmann La Roche Benzoxazinderivate als 5-ht6-modulatoren und deren verwendungen
AR040967A1 (es) * 2002-08-12 2005-04-27 Janssen Pharmaceutica Nv Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
CA2494557C (en) 2002-08-15 2011-10-18 Janssen Pharmaceutica N.V. Fused heterocyclic isoxazoline derivatives and their use as anti-depressants
AU2003257407A1 (en) * 2002-08-29 2004-03-19 H. Lundbeck A/S S-(+)-3-{1-(2-(2,3-dihydro-1h-indol-3-yl)ethyl)-3,6-dihydro-2h-pyridin-4-yl}-6-chloro-1h-indole and acid addition salts thereof
GB0227240D0 (en) * 2002-11-21 2002-12-31 Glaxo Group Ltd Compounds
US7235569B2 (en) 2003-05-02 2007-06-26 Wyeth Piperidinyl indole and tetrohydropyridinyl indole derivatives and method of their use
US7276603B2 (en) 2003-05-02 2007-10-02 Wyeth Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use
JP2008523030A (ja) * 2004-12-08 2008-07-03 ソルベイ・フアーマシユーチカルズ・ベー・ブイ 部分的ドーパミン−ｄ２受容体作動性とセロトニン再摂取阻害の組み合わせを示すフェニルピペラジン誘導体
US7807671B2 (en) * 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
CA2668959A1 (en) 2006-11-09 2008-05-15 F. Hoffmann-La Roche Ag Indole and benzofuran 2-carboxamide derivatives
CA2718138A1 (en) * 2008-03-14 2009-09-17 Timo Heinrich Azaindole compounds for treatment of central nervous system disorders
CN103420989B (zh) * 2012-05-15 2016-03-23 华中科技大学 苯并二噁烷类衍生物及其应用
EP3027607B1 (en) 2013-07-29 2020-08-26 Sunshine Lake Pharma Co., Ltd. Substituted heteroaryl compounds and methods of use thereof
CN105732591B (zh) * 2014-12-31 2019-10-25 广东东阳光药业有限公司 取代的哌嗪化合物及其使用方法和用途
WO2017012579A1 (zh) * 2015-07-23 2017-01-26 广东东阳光药业有限公司 取代的吲哚化合物及其使用方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9305641D0 (en) * 1993-03-18 1993-05-05 Merck Sharp & Dohme Therapeutic agents
DE4414113A1 (de) * 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
ZA9711376B (en) * 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives

Also Published As

Publication number Publication date
AU765317C (en) 2004-05-20
CA2335711A1 (en) 1999-12-29
AU765317B2 (en) 2003-09-18
WO1999067237A1 (en) 1999-12-29
NO20006460D0 (no) 2000-12-18
EP1089997A1 (en) 2001-04-11
JP2003521443A (ja) 2003-07-15
BG105136A (en) 2001-09-28
HUP0101475A2 (hu) 2001-10-28
HRP20000847A2 (en) 2001-12-31
NZ508506A (en) 2004-01-30
AU4359299A (en) 2000-01-10
NO20006460L (no) 2001-02-19

Similar Documents

Publication Publication Date Title
HUP0101475A3 (en) 4,5,6 and 7-indole and indoline derivatives, their preparation and use
IL141479A0 (en) Substituted phenyl derivatives, their preparation and use
IL139286A0 (en) Polyol-ifn-beta conjugates, their preparation and use
IL140236A0 (en) 1,3-oxazoline and 1,3--thiazoline derivatives, their preparation, and their use as pesticides
IL143095A0 (en) 3,3-biarylpiperidine and 2,2-biarylmorpholine derivatives
HK1036974A1 (en) Indole derivatives and medicinal compositions containing the same.
PL342060A1 (en) Derivatives of 1,3,4-oxadiaxolone
ZA989664B (en) 3-substituted tetrahydropyrimidinone derivatives, their preparation and use.
AU3693797A (en) 1,3-dimethyl-5-fluoro-pyrazole-4-carboxamide derivatives, their preparation and their use as microbicides
IL139962A0 (en) 4,5,6 and 7-indole and indoline derivatives, their preparation and use
IL143082A0 (en) Benzofuran derivatives, their preparation and use
ZA989571B (en) 2-Substituted 1,2-Benzoisonthiazole derivatives, their preparation and use.
GB2324090B (en) 5,6-O-alkylidene glucono-1(4)-lactones and derivatives thereof,their preparation and use
AU4506499A (en) Novel 2,4-diaminophenol derivatives and the use thereof
AU3147500A (en) Fused 1,4-thiazine-2-carbonitrile derivatives, their preparation and use
ZA986237B (en) Indole and 2,3-dihydroindole derivatives their preparation and use
SI1007523T1 (en) Indole and 2,3-dihydroindole derivatives, their preparation and use
AU4605399A (en) Novel 3,4-diaminophenol derivatives and their use
PL347934A1 (en) Benzofuran derivatives, their preparation and use
SI1140835T1 (en) 3,3-biarylpiperidine and 2,2-biarylmorpholine derivatives
AU6327199A (en) Substituted 3,3-diamino-2-propenenitriles, their preparation and use
HK1043737A1 (zh) 含3，3-經取代二氫吲衍生物之避孕組合物及其使用
SI1123274T1 (en) Substituted phenyl derivatives, their preparation and use
MXPA01011297A (es) Composiciones contraceptivas que contienen derivados de indolina 3,3-sustituidos, y usos de las mismas.
ZA9811564B (en) Derivatives of 1,3,4-oxadiazolone