BG103288A - Method for the preparation of contrast forms - Google Patents

Method for the preparation of contrast forms

Info

Publication number
BG103288A
BG103288A BG103288A BG10328899A BG103288A BG 103288 A BG103288 A BG 103288A BG 103288 A BG103288 A BG 103288A BG 10328899 A BG10328899 A BG 10328899A BG 103288 A BG103288 A BG 103288A
Authority
BG
Bulgaria
Prior art keywords
preparation
acid
acylation
alkylation
derivative
Prior art date
Application number
BG103288A
Other languages
Bulgarian (bg)
English (en)
Inventor
Trygve Gulbrandsen
Odd INGVOLDSTAD
Lars HOLMAAS
Original Assignee
Nycomed Imaging A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging A/S filed Critical Nycomed Imaging A/S
Publication of BG103288A publication Critical patent/BG103288A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Glass Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Exposure Of Semiconductors, Excluding Electron Or Ion Beam Exposure (AREA)
  • Hydrogenated Pyridines (AREA)
BG103288A 1996-08-29 1999-03-26 Method for the preparation of contrast forms BG103288A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9618055.9A GB9618055D0 (en) 1996-08-29 1996-08-29 Process
PCT/GB1997/002335 WO1998008805A1 (en) 1996-08-29 1997-08-29 Process for the preparation of contrast agents

Publications (1)

Publication Number Publication Date
BG103288A true BG103288A (en) 2000-01-31

Family

ID=10799119

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103288A BG103288A (en) 1996-08-29 1999-03-26 Method for the preparation of contrast forms

Country Status (21)

Country Link
EP (1) EP0923537B1 (hu)
JP (1) JP4113587B2 (hu)
KR (1) KR100539647B1 (hu)
CN (1) CN1092182C (hu)
AT (1) ATE207880T1 (hu)
AU (1) AU717842B2 (hu)
BG (1) BG103288A (hu)
BR (1) BR9711358A (hu)
CA (1) CA2263426A1 (hu)
CZ (1) CZ296230B6 (hu)
DE (1) DE69707901T2 (hu)
EE (1) EE9900081A (hu)
ES (1) ES2167014T3 (hu)
GB (1) GB9618055D0 (hu)
HU (1) HUP9903852A3 (hu)
IL (1) IL128685A0 (hu)
NO (1) NO322141B1 (hu)
NZ (1) NZ334818A (hu)
PL (1) PL193698B1 (hu)
SK (1) SK26399A3 (hu)
WO (1) WO1998008805A1 (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
GB9903109D0 (en) 1999-02-11 1999-04-07 Nycomed Imaging As Process
ITMI20010773A1 (it) * 2001-04-11 2002-10-11 Chemi Spa Processo per la produzione di ioexolo ad elevata purezza
CN100344606C (zh) * 2005-12-28 2007-10-24 江苏省原子医学研究所 一种碘昔兰的制备方法
US20110021822A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents
CN103058880B (zh) * 2011-10-21 2015-08-05 连云港润众制药有限公司 碘克沙醇及其合成中间体的制备方法
EP3077367B1 (en) * 2013-12-06 2018-07-11 GE Healthcare AS Alternative process for the purification of an intermediate in the synthesis of non-ionic x-ray contrast agents
EP3077368B1 (en) 2013-12-06 2018-07-11 GE Healthcare AS Alternative process for the purification of an intermediate in the synthesis of non-ionic x-ray contrast agents
CN104356023B (zh) * 2014-10-29 2016-04-13 武汉工程大学 一种碘曲仑的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2132530B1 (hu) * 1971-04-07 1974-08-02 Guerbet Lab Andre
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DK162045C (da) * 1982-10-01 1992-02-10 Nyegaard & Co As Trijodbenzenderivater, fremgangsmaade til fremstilling deraf og radiologiske praeparater indeholdende saadanne forbindelser
US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
EP0233249B1 (en) * 1985-08-09 1993-11-24 Cook Imaging Corporation Non-ionic polyol contrast media from ionic contrast media

Also Published As

Publication number Publication date
DE69707901T2 (de) 2002-07-18
ATE207880T1 (de) 2001-11-15
JP4113587B2 (ja) 2008-07-09
NO990890D0 (no) 1999-02-25
KR20000035944A (ko) 2000-06-26
NZ334818A (en) 2000-08-25
HUP9903852A3 (en) 2001-08-28
EP0923537B1 (en) 2001-10-31
AU717842B2 (en) 2000-04-06
EE9900081A (et) 1999-10-15
ES2167014T3 (es) 2002-05-01
AU4026797A (en) 1998-03-19
NO322141B1 (no) 2006-08-21
IL128685A0 (en) 2000-01-31
PL193698B1 (pl) 2007-03-30
DE69707901D1 (de) 2001-12-06
CN1092182C (zh) 2002-10-09
CA2263426A1 (en) 1998-03-05
EP0923537A1 (en) 1999-06-23
CZ67099A3 (cs) 1999-08-11
HUP9903852A2 (hu) 2000-03-28
GB9618055D0 (en) 1996-10-09
BR9711358A (pt) 1999-08-17
CN1228762A (zh) 1999-09-15
KR100539647B1 (ko) 2005-12-29
CZ296230B6 (cs) 2006-02-15
SK26399A3 (en) 2000-03-13
WO1998008805A1 (en) 1998-03-05
JP2000517313A (ja) 2000-12-26
PL331821A1 (en) 1999-08-02
NO990890L (no) 1999-02-25

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