BG103251A - Oxydiazols, methods for their preparation and application as medicamentous forms - Google Patents
Oxydiazols, methods for their preparation and application as medicamentous formsInfo
- Publication number
- BG103251A BG103251A BG103251A BG10325199A BG103251A BG 103251 A BG103251 A BG 103251A BG 103251 A BG103251 A BG 103251A BG 10325199 A BG10325199 A BG 10325199A BG 103251 A BG103251 A BG 103251A
- Authority
- BG
- Bulgaria
- Prior art keywords
- preparation
- methods
- application
- oxydiazols
- medicamentous forms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19643037A DE19643037A1 (de) | 1996-10-18 | 1996-10-18 | Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel |
PCT/EP1997/005693 WO1998017652A1 (fr) | 1996-10-18 | 1997-10-15 | Oxadiazoles, procedes permettant de les preparer et leur utilisation comme medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
BG103251A true BG103251A (en) | 2000-02-29 |
Family
ID=7809114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG103251A Pending BG103251A (en) | 1996-10-18 | 1999-03-15 | Oxydiazols, methods for their preparation and application as medicamentous forms |
Country Status (32)
Country | Link |
---|---|
US (1) | US6277872B1 (fr) |
EP (1) | EP0934288B1 (fr) |
JP (1) | JP3333523B2 (fr) |
KR (1) | KR20000049253A (fr) |
CN (1) | CN1086698C (fr) |
AR (1) | AR008496A1 (fr) |
AT (1) | ATE315034T1 (fr) |
AU (1) | AU737552B2 (fr) |
BG (1) | BG103251A (fr) |
BR (1) | BR9714354A (fr) |
CA (1) | CA2268954C (fr) |
CO (1) | CO4920253A1 (fr) |
CZ (1) | CZ138099A3 (fr) |
DE (2) | DE19643037A1 (fr) |
EE (1) | EE9900147A (fr) |
ES (1) | ES2256880T3 (fr) |
HK (1) | HK1020956A1 (fr) |
HR (1) | HRP970553A2 (fr) |
HU (1) | HUP0001652A3 (fr) |
ID (1) | ID18613A (fr) |
IL (1) | IL129315A0 (fr) |
NO (1) | NO312512B1 (fr) |
NZ (1) | NZ335598A (fr) |
PE (1) | PE11199A1 (fr) |
PL (1) | PL332432A1 (fr) |
RU (1) | RU2182905C2 (fr) |
SK (1) | SK49999A3 (fr) |
TR (1) | TR199900848T2 (fr) |
TW (1) | TW413678B (fr) |
WO (1) | WO1998017652A1 (fr) |
YU (1) | YU40997A (fr) |
ZA (1) | ZA979220B (fr) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19816880A1 (de) | 1998-04-17 | 1999-10-21 | Boehringer Ingelheim Pharma | Neue Diphenyl-substituierte 5-Ring-Heterocyclen, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel |
IT1300056B1 (it) | 1998-04-17 | 2000-04-05 | Boehringer Ingelheim Italia | Eterocicli con anello a 6 termini difenil-sostituiti loro procedimento di preparazione e loro impiego come farmaci |
US6107313A (en) * | 1998-10-02 | 2000-08-22 | Combichem, Inc. | Dopamine receptor antagonists |
DE60027546T2 (de) | 1999-02-15 | 2007-04-26 | Eisai Co., Ltd. | Heterodiazinon-derivate |
PT1070708E (pt) | 1999-07-21 | 2004-05-31 | Hoffmann La Roche | Derivados de triazol |
EP1582519A3 (fr) * | 1999-08-19 | 2005-12-21 | Nps Pharmaceuticals, Inc. | Composes heteropolycycliques et leur utilisation comme antagonistes des recepteurs glutamiques metabotropes |
US6660753B2 (en) | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
ES2250177T3 (es) * | 1999-08-19 | 2006-04-16 | Nps Pharmaceuticals, Inc. | Compuestos heteropoliciclicos y su uso como antagonistas de receptores de glutamato metabotropico. |
US6579880B2 (en) * | 2000-06-06 | 2003-06-17 | Ortho-Mcneil Pharmaceutical, Inc. | Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8 |
EP2177520A1 (fr) | 2000-06-12 | 2010-04-21 | Eisai R&D Management Co., Ltd. | 1,5-Di(aryl ou hétéroaryl)-3-halo-2(1H)-pyridones comme intermédiaires pour la préparation d'inhibiteurs du récepteur AMPA |
AU2001290229B2 (en) * | 2000-09-18 | 2006-12-07 | Eisai R&D Management Co., Ltd. | Pyridazinones and triazinones and medicinal use thereof |
IL157491A0 (en) * | 2001-02-21 | 2004-03-28 | Nps Pharmeceuticals Inc | Heteropolycyclic compounds and pharmaceutical compositions containing the same |
WO2003029210A2 (fr) * | 2001-10-04 | 2003-04-10 | Merck & Co. Inc. | Composes de tetrazole substitues par heteroaryle, modulateurs du recepteur-5 metabotropique du glutamate |
MY151199A (en) | 2001-11-02 | 2014-04-30 | Rigel Pharmaceuticals Inc | Substituted diphenyl heterocycles useful for treating hcv infection |
GB0129260D0 (en) | 2001-12-06 | 2002-01-23 | Eisai London Res Lab Ltd | Pharmaceutical compositions and their uses |
EP1530569A2 (fr) | 2002-08-23 | 2005-05-18 | Rigel Pharmaceuticals, Inc. | Heterocycles a substitution pyridyle utiles dans le traitement de l'infection par le virus de l'hepatite c |
GB0303503D0 (en) * | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
WO2004099164A1 (fr) * | 2003-05-02 | 2004-11-18 | Rigel Pharmaceuticals, Inc. | Diphenyl isoxazoles, pyrazoles et oxadiazoles substitues, destines au traitement d'une infection par le vhc |
US7326790B2 (en) | 2003-05-02 | 2008-02-05 | Rigel Pharmaceuticals, Inc. | Diphenylisoxazole compounds and hydro isomers thereof |
US7220745B2 (en) | 2003-05-15 | 2007-05-22 | Rigel Pharmaceuticals | Heterocyclic compounds useful to treat HCV |
WO2005049065A2 (fr) | 2003-11-19 | 2005-06-02 | Rigel Pharmaceuticals, Inc. | Combinaisons efficaces d'un point de vue synergique de composes dihaloacetamide et d'interferon ou de ribavirine contre les infections par le virus de l'hepatite c (vhc) |
CA2549955A1 (fr) | 2003-12-24 | 2005-07-07 | Prosidion Limited | Derives heterocycliques utilises comme agonistes des recepteurs gpcr |
US7514434B2 (en) | 2004-02-23 | 2009-04-07 | Rigel Pharmaceuticals, Inc. | Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof |
MY148809A (en) | 2004-07-06 | 2013-05-31 | Eisai R&D Man Co Ltd | Crystals of 1,2-dihydropyridine compound and their production process |
JPWO2006109876A1 (ja) * | 2005-04-08 | 2008-11-20 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 不随意運動治療剤 |
EP1883633A2 (fr) | 2005-05-02 | 2008-02-06 | Rigel Pharmaceuticals, Inc. | Composes heterocycliques antiviraux comprenant des groupes metabolisables et leurs utilisations |
GB0510142D0 (en) * | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds A1 |
HUP0500920A2 (en) * | 2005-10-05 | 2007-07-30 | Richter Gedeon Nyrt | Oxadiazole derivatives, process for their preparation and their use |
MX2009006304A (es) * | 2006-12-15 | 2009-06-23 | Abbott Lab | Nuevos compuestos de oxadiazol. |
US20110207704A1 (en) * | 2006-12-15 | 2011-08-25 | Abbott Laboratories | Novel Oxadiazole Compounds |
JO2701B1 (en) | 2006-12-21 | 2013-03-03 | جلاكسو جروب ليميتد | Vehicles |
WO2009043890A1 (fr) * | 2007-10-04 | 2009-04-09 | Merck Serono S.A. | Composés oxadiazole diarylés |
US9045442B2 (en) * | 2007-12-21 | 2015-06-02 | University Of Notre Dame Du Lac | Antibacterial compounds and methods of using same |
TR201904041T4 (tr) | 2008-06-09 | 2019-04-22 | Max Planck Gesellschaft | Protein agregasyonu ile bağlantılı hastalıklarda ve/veya nörodejeneratif hastalıklarda rol oynayan proteinlerin agregasyonunu inhibe etmeye yönelik ilaçlar. |
WO2011047129A1 (fr) | 2009-10-15 | 2011-04-21 | Southern Research Institute | Traitement de maladies neurodégénératives, cause d'amélioration de la mémoire et analyse pour évaluer des composés associés |
AU2013305663B2 (en) * | 2012-08-24 | 2017-11-02 | Treventis Corporation | Benzofurazan anti-amyloid compounds and methods |
ES2734432T3 (es) | 2014-02-27 | 2019-12-05 | Treventis Corp | Compuestos antiamiloides que contienen benzofurazano |
US9884858B2 (en) | 2014-04-24 | 2018-02-06 | Sumitomo Chemical Company, Limited | Diaryl-azole compound |
US10662164B2 (en) | 2014-09-25 | 2020-05-26 | University Of Notre Dame Du Lac | Non-beta lactam antibiotics |
CN107286174B (zh) * | 2016-04-11 | 2020-08-18 | 上海勋和医药科技有限公司 | 取代2,4-(1h,3h)嘧啶二酮作为parp抑制剂及其应用 |
WO2018049404A1 (fr) | 2016-09-12 | 2018-03-15 | University Of Notre Dame Du Lac | Composés pour le traitement d'une infection par clostridium difficile |
US11180518B2 (en) | 2017-05-12 | 2021-11-23 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Phenyl-heterocycle-phenyl derivatives for use in the treatment or prevention of melanoma |
US10676467B2 (en) | 2017-06-30 | 2020-06-09 | Washington University | Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof |
MX2021006317A (es) | 2018-12-14 | 2021-08-11 | Eisai R&D Man Co Ltd | Formulaciones farmaceuticas de base acuosa de compuestos de 1,2-dihidropiridina. |
WO2023042888A1 (fr) | 2021-09-15 | 2023-03-23 | 国立大学法人 琉球大学 | Composition pharmaceutique destinée à être mise en œuvre dans le traitement soit du déclin des fonctions cognitives, soit de la surcharge pondérale ou de l'obésité |
WO2023042887A1 (fr) | 2021-09-15 | 2023-03-23 | 国立大学法人 琉球大学 | Composition pharmaceutique destinée à être mise en œuvre dans le traitement soit du déclin des fonctions cognitives, soit de la surcharge pondérale ou de l'obésité |
EP4173485A1 (fr) | 2021-10-27 | 2023-05-03 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Composés inhibant l'agrégation de protéine pour la lutte contre les maladies des plantes |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4003909A (en) * | 1974-07-22 | 1977-01-18 | E. R. Squibb & Sons, Inc. | [(1,2,4-Oxadiazol-3-yl)phenyl]carbamic or thiocarbamic acid esters |
JPS52272A (en) * | 1975-10-17 | 1977-01-05 | Takeda Chem Ind Ltd | Process for preparing 1,2,4-oxadiazole derivatives |
DE2801509A1 (de) * | 1978-01-12 | 1979-07-19 | Schering Ag | 1,2,4-oxadiazolderivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende selektive herbizide mittel |
JPS58150576A (ja) * | 1982-03-03 | 1983-09-07 | Sumitomo Chem Co Ltd | 新規な1,2,4−オキサジアゾ−ル誘導体 |
US4871753A (en) * | 1986-12-12 | 1989-10-03 | Ciba-Geigy Corporation | 3-Phenyl-5-trifluoromethyl-1,2,4-oxadiazole compounds which are useful pesticides |
DE3905242A1 (de) * | 1989-02-21 | 1990-08-23 | Basf Ag | Verfahren zur herstellung von phenyloxdiazolylanilinen |
JPH02250873A (ja) * | 1989-03-24 | 1990-10-08 | Mitsubishi Petrochem Co Ltd | 1,2,4―オキサジアゾール誘導体及びそれを有効成分とする除草剤 |
NZ234760A (en) * | 1989-08-18 | 1991-09-25 | Sterling Drug Inc | Antiviral oxazole compounds and compositions |
DK443489D0 (da) * | 1989-09-08 | 1989-09-08 | Ferrosan As | Substituerede urinstofforbindelser, deres fremstilling og anvendelse |
JPH04295470A (ja) * | 1991-03-22 | 1992-10-20 | Wakamoto Pharmaceut Co Ltd | モノアミンオキシダーゼ−b酵素阻害活性を有する1,2,4−オキサジアゾール誘導体及びその製造法 |
EP0596933A1 (fr) * | 1991-08-03 | 1994-05-18 | Smithkline Beecham Plc | Antagonistes du recepteur 5-ht4 |
DE4401108A1 (de) * | 1994-01-17 | 1995-07-20 | Bayer Ag | 1,2,4-Oxadiazol-Derivate |
DE4401107A1 (de) * | 1994-01-17 | 1995-07-20 | Bayer Ag | 3-Aryl-alkenyl-1,2,4-oxadiazol-Derivate |
DE19528189A1 (de) * | 1995-08-01 | 1997-02-06 | Basf Ag | Benzolderivate mit einem heterocyclischen Rest |
-
1996
- 1996-10-18 DE DE19643037A patent/DE19643037A1/de not_active Withdrawn
-
1997
- 1997-10-15 EE EEP199900147A patent/EE9900147A/xx unknown
- 1997-10-15 ZA ZA9709220A patent/ZA979220B/xx unknown
- 1997-10-15 DE DE59712543T patent/DE59712543D1/de not_active Expired - Lifetime
- 1997-10-15 ES ES97911227T patent/ES2256880T3/es not_active Expired - Lifetime
- 1997-10-15 IL IL12931597A patent/IL129315A0/xx unknown
- 1997-10-15 TR TR1999/00848T patent/TR199900848T2/xx unknown
- 1997-10-15 AU AU48676/97A patent/AU737552B2/en not_active Ceased
- 1997-10-15 WO PCT/EP1997/005693 patent/WO1998017652A1/fr active IP Right Grant
- 1997-10-15 HU HU0001652A patent/HUP0001652A3/hu unknown
- 1997-10-15 CN CN97198866A patent/CN1086698C/zh not_active Expired - Fee Related
- 1997-10-15 PE PE1997000910A patent/PE11199A1/es not_active Application Discontinuation
- 1997-10-15 EP EP97911227A patent/EP0934288B1/fr not_active Expired - Lifetime
- 1997-10-15 JP JP50563998A patent/JP3333523B2/ja not_active Expired - Lifetime
- 1997-10-15 SK SK499-99A patent/SK49999A3/sk unknown
- 1997-10-15 BR BR9714354-5A patent/BR9714354A/pt not_active IP Right Cessation
- 1997-10-15 RU RU99111781/04A patent/RU2182905C2/ru not_active IP Right Cessation
- 1997-10-15 KR KR1019990703360A patent/KR20000049253A/ko not_active Application Discontinuation
- 1997-10-15 AT AT97911227T patent/ATE315034T1/de active
- 1997-10-15 NZ NZ335598A patent/NZ335598A/en unknown
- 1997-10-15 PL PL97332432A patent/PL332432A1/xx unknown
- 1997-10-15 CA CA002268954A patent/CA2268954C/fr not_active Expired - Fee Related
- 1997-10-15 CZ CZ991380A patent/CZ138099A3/cs unknown
- 1997-10-15 US US09/284,382 patent/US6277872B1/en not_active Expired - Lifetime
- 1997-10-16 HR HR19643037.2A patent/HRP970553A2/hr not_active Application Discontinuation
- 1997-10-16 ID IDP973449A patent/ID18613A/id unknown
- 1997-10-16 YU YU40997A patent/YU40997A/sh unknown
- 1997-10-17 CO CO97061157A patent/CO4920253A1/es unknown
- 1997-10-17 AR ARP970104812A patent/AR008496A1/es not_active Application Discontinuation
- 1997-10-18 TW TW086115386A patent/TW413678B/zh not_active IP Right Cessation
-
1999
- 1999-03-15 BG BG103251A patent/BG103251A/xx active Pending
- 1999-04-16 NO NO19991815A patent/NO312512B1/no not_active IP Right Cessation
- 1999-12-29 HK HK99106174A patent/HK1020956A1/xx not_active IP Right Cessation
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