BG102235A - Method for the reduction of the quantity of exogenous insulin applied to patients suffering from insulin-independent diabetes melitus - Google Patents
Method for the reduction of the quantity of exogenous insulin applied to patients suffering from insulin-independent diabetes melitusInfo
- Publication number
- BG102235A BG102235A BG102235A BG10223598A BG102235A BG 102235 A BG102235 A BG 102235A BG 102235 A BG102235 A BG 102235A BG 10223598 A BG10223598 A BG 10223598A BG 102235 A BG102235 A BG 102235A
- Authority
- BG
- Bulgaria
- Prior art keywords
- insulin
- reduction
- patients suffering
- independent diabetes
- diabetes melitus
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 4
- 102000004877 Insulin Human genes 0.000 title 2
- 108090001061 Insulin Proteins 0.000 title 2
- 229940125396 insulin Drugs 0.000 title 2
- 206010012601 diabetes mellitus Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US209895P | 1995-08-10 | 1995-08-10 | |
| PCT/US1996/012430 WO1997005875A2 (en) | 1995-08-10 | 1996-07-29 | A method of reducing the amount of exogenous insulin administered to a patient having noninsulin-dependent diabetes mellitus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG102235A true BG102235A (en) | 1998-09-30 |
Family
ID=21699238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG102235A BG102235A (en) | 1995-08-10 | 1998-02-05 | Method for the reduction of the quantity of exogenous insulin applied to patients suffering from insulin-independent diabetes melitus |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0851757A2 (cs) |
| JP (1) | JPH11510508A (cs) |
| KR (1) | KR19990036290A (cs) |
| CN (1) | CN1192683A (cs) |
| AU (1) | AU724989B2 (cs) |
| BG (1) | BG102235A (cs) |
| CA (1) | CA2221241A1 (cs) |
| CZ (1) | CZ32998A3 (cs) |
| EA (1) | EA199800177A1 (cs) |
| HU (1) | HUP9802543A2 (cs) |
| IL (1) | IL122191A0 (cs) |
| NO (1) | NO980556L (cs) |
| NZ (1) | NZ313874A (cs) |
| SK (1) | SK16498A3 (cs) |
| WO (1) | WO1997005875A2 (cs) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9711683D0 (en) * | 1997-06-05 | 1997-08-06 | Smithkline Beecham Plc | Composition |
| GB9712866D0 (en) * | 1997-06-18 | 1997-08-20 | Smithkline Beecham Plc | Novel method of treatment |
| GB2335597A (en) * | 1998-03-27 | 1999-09-29 | Glaxo Group Ltd | Stereoisomers of Troglitazone in the Treatment of Diabetes |
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| EP1087963B1 (en) | 1998-06-19 | 2004-08-25 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| FR2838968A1 (fr) * | 2002-04-30 | 2003-10-31 | Lipha | Association d'insuline et d'un derive de thiazolidinedione et son utilisation pour traiter le diabete |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
| US4873255A (en) * | 1987-02-04 | 1989-10-10 | Sankyo Company Limited | Thiazolidinone derivatives, their preparation and their use |
| US5478852C1 (en) * | 1993-09-15 | 2001-03-13 | Sankyo Co | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus |
| TW438587B (en) | 1995-06-20 | 2001-06-07 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
-
1996
- 1996-07-29 HU HU9802543A patent/HUP9802543A2/hu unknown
- 1996-07-29 IL IL12219196A patent/IL122191A0/xx unknown
- 1996-07-29 CZ CZ98329A patent/CZ32998A3/cs unknown
- 1996-07-29 KR KR1019980700958A patent/KR19990036290A/ko not_active Ceased
- 1996-07-29 EA EA199800177A patent/EA199800177A1/ru unknown
- 1996-07-29 JP JP9508479A patent/JPH11510508A/ja not_active Ceased
- 1996-07-29 CN CN96196191A patent/CN1192683A/zh active Pending
- 1996-07-29 AU AU66411/96A patent/AU724989B2/en not_active Withdrawn - After Issue
- 1996-07-29 SK SK164-98A patent/SK16498A3/sk unknown
- 1996-07-29 WO PCT/US1996/012430 patent/WO1997005875A2/en not_active Application Discontinuation
- 1996-07-29 EP EP96926171A patent/EP0851757A2/en not_active Withdrawn
- 1996-07-29 CA CA002221241A patent/CA2221241A1/en not_active Abandoned
- 1996-07-29 NZ NZ313874A patent/NZ313874A/xx unknown
-
1998
- 1998-02-05 BG BG102235A patent/BG102235A/xx unknown
- 1998-02-09 NO NO980556A patent/NO980556L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11510508A (ja) | 1999-09-14 |
| NO980556D0 (no) | 1998-02-09 |
| SK16498A3 (en) | 1999-03-12 |
| WO1997005875A3 (en) | 1997-03-27 |
| CN1192683A (zh) | 1998-09-09 |
| NO980556L (no) | 1998-02-09 |
| CZ32998A3 (cs) | 1998-10-14 |
| HUP9802543A2 (hu) | 1999-07-28 |
| WO1997005875A2 (en) | 1997-02-20 |
| NZ313874A (en) | 2000-09-29 |
| CA2221241A1 (en) | 1997-02-20 |
| AU724989B2 (en) | 2000-10-05 |
| IL122191A0 (en) | 1998-04-05 |
| KR19990036290A (ko) | 1999-05-25 |
| AU6641196A (en) | 1997-03-05 |
| EP0851757A2 (en) | 1998-07-08 |
| EA199800177A1 (ru) | 1998-10-29 |
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