BG101251A - Биосъвместим хидрогел - Google Patents

Биосъвместим хидрогел

Info

Publication number
BG101251A
BG101251A BG101251A BG10125197A BG101251A BG 101251 A BG101251 A BG 101251A BG 101251 A BG101251 A BG 101251A BG 10125197 A BG10125197 A BG 10125197A BG 101251 A BG101251 A BG 101251A
Authority
BG
Bulgaria
Prior art keywords
hydrogel
linked
polymerization
acrylamide
cross
Prior art date
Application number
BG101251A
Other languages
English (en)
Other versions
BG62915B1 (bg
Inventor
Original Assignee
Малое Внедренческое Предприятие "Интерфалл"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21689009&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG101251(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Малое Внедренческое Предприятие "Интерфалл" filed Critical Малое Внедренческое Предприятие "Интерфалл"
Publication of BG101251A publication Critical patent/BG101251A/bg
Publication of BG62915B1 publication Critical patent/BG62915B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Биологично съвместимият хидрогел се прилага при коригирането на козметични и функционални дефекти, например при ендопротезиране на гръдни жлези, гласни струни, пениси и други, за създаване на вътрешнотъканни депа на лекарствени препарати с пролонгирано действие, за използване като електропроводима имерсионна среда и за постоянно запълване на кухини. Хидрогелът включва полимер на базата на акриламид, получен при използването на инициатор на радикалната полимеризация в апирогенна вода, която е дисперсионна среда. За да се подобрят гъвкавостта,формоустойчивостта и стабилността на обемните импланти, съответно тяхната терапевтична или козметична ефективност, по-специално при ендопротезирането, хидрогелът съдържа напречно свързан (омрежен) полиакриламид, получен при използванетона биологично поносим напречносвързващ (омрежващ) агент, за предпочитане метилен-бис-акриламид, и като полимеризиращ инициатор на полимеризацията за предпочитане от смес от амониев персулфат и тетраметилетилендиамин. Предпочитаната концентрация на полимера в хидрогела е от 3,5 до 9% тегл.
BG101251A 1994-08-10 1997-02-20 Биосъвместим хидрогел BG62915B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
UA94086726A UA10911C2 (uk) 1994-08-10 1994-08-10 Біосумісhий гідрогель
PCT/UA1994/000022 WO1996004943A1 (fr) 1994-08-10 1994-08-12 Hyrogel biocompatible

Publications (2)

Publication Number Publication Date
BG101251A true BG101251A (bg) 1997-09-30
BG62915B1 BG62915B1 (bg) 2000-11-30

Family

ID=21689009

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101251A BG62915B1 (bg) 1994-08-10 1997-02-20 Биосъвместим хидрогел

Country Status (22)

Country Link
US (2) US5798096A (bg)
EP (1) EP0742022B1 (bg)
JP (1) JP3359036B2 (bg)
KR (1) KR100316212B1 (bg)
CN (1) CN1058639C (bg)
AT (1) ATE190508T1 (bg)
AU (1) AU696773B2 (bg)
BG (1) BG62915B1 (bg)
BR (1) BR9408609A (bg)
CA (1) CA2195957C (bg)
CZ (1) CZ297126B6 (bg)
DE (1) DE69423520T2 (bg)
DK (1) DK0742022T3 (bg)
ES (1) ES2145841T3 (bg)
FI (1) FI970315A (bg)
GR (1) GR3033694T3 (bg)
HU (1) HU9603434D0 (bg)
NO (1) NO310446B1 (bg)
PT (1) PT742022E (bg)
RU (1) RU2067873C1 (bg)
UA (1) UA10911C2 (bg)
WO (1) WO1996004943A1 (bg)

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Also Published As

Publication number Publication date
KR970704483A (ko) 1997-09-06
RU2067873C1 (ru) 1996-10-20
CZ22497A3 (en) 1997-07-16
EP0742022B1 (en) 2000-03-15
NO970330L (no) 1997-02-10
USRE38913E1 (en) 2005-12-06
JPH10503950A (ja) 1998-04-14
RU95100525A (ru) 1996-11-27
CZ297126B6 (cs) 2006-09-13
KR100316212B1 (ko) 2002-06-20
CN1058639C (zh) 2000-11-22
FI970315A0 (fi) 1997-01-24
CA2195957C (en) 2005-08-02
BG62915B1 (bg) 2000-11-30
NO310446B1 (no) 2001-07-09
JP3359036B2 (ja) 2002-12-24
ES2145841T3 (es) 2000-07-16
CA2195957A1 (en) 1996-02-22
NO970330D0 (no) 1997-01-24
DK0742022T3 (da) 2000-08-21
HU9603434D0 (en) 1997-02-28
FI970315A (fi) 1997-01-24
EP0742022A4 (en) 1996-11-25
US5798096A (en) 1998-08-25
DE69423520D1 (de) 2000-04-20
ATE190508T1 (de) 2000-04-15
PT742022E (pt) 2000-09-29
AU696773B2 (en) 1998-09-17
AU7794094A (en) 1996-03-07
BR9408609A (pt) 1997-12-23
CN1156411A (zh) 1997-08-06
EP0742022A1 (en) 1996-11-13
DE69423520T2 (de) 2000-10-19
GR3033694T3 (en) 2000-10-31
WO1996004943A1 (fr) 1996-02-22
UA10911C2 (uk) 1996-12-25

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