BG101080A - Метод за получаване на лекарствена форма на карбамазепин със забавено освобождаване на активното вещество - Google Patents

Метод за получаване на лекарствена форма на карбамазепин със забавено освобождаване на активното вещество

Info

Publication number
BG101080A
BG101080A BG101080A BG10108096A BG101080A BG 101080 A BG101080 A BG 101080A BG 101080 A BG101080 A BG 101080A BG 10108096 A BG10108096 A BG 10108096A BG 101080 A BG101080 A BG 101080A
Authority
BG
Bulgaria
Prior art keywords
carbamasepin
active substance
delayed release
medicamentous form
medicamentous
Prior art date
Application number
BG101080A
Other languages
English (en)
Other versions
BG62794B1 (bg
Inventor
Karl-Friedrich Landgraf
Sabine Reiss
Eberhard Schubert
Original Assignee
Awd.Pharma Gmbh & Co.Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Awd.Pharma Gmbh & Co.Kg filed Critical Awd.Pharma Gmbh & Co.Kg
Publication of BG101080A publication Critical patent/BG101080A/bg
Publication of BG62794B1 publication Critical patent/BG62794B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Abstract

Методът за получаване на лекарствена форма на карбамазепин за орално приложение със забавено освобождаване на активното вещество включва нанасяне на водна дисперсия на полимер върху кристалите карбамазепин, съдържаща пластификатор,без да се образувадихидрат на карбамазепина. Кристалите карбамазепин с водно покритие могат да се смесват с подходящипомощни вещества, да се преработват наделими таблетки или да се пълнят в капсули.
BG101080A 1994-07-01 1996-12-28 Метод за получаване на лекарствена форма на карбамазепин съсзабавено освобождаване на активното вещество BG62794B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19944423078 DE4423078B4 (de) 1994-07-01 1994-07-01 Verfahren zur Herstellung einer Carbamazepin-Arzneiform mit verzögerter Wirkstofffreisetzung
PCT/DE1995/000805 WO1996001112A1 (de) 1994-07-01 1995-06-22 Carbamazepin-arzneiform mit verzögerter wirkstofffreisetzung

Publications (2)

Publication Number Publication Date
BG101080A true BG101080A (bg) 1997-08-29
BG62794B1 BG62794B1 (bg) 2000-08-31

Family

ID=6522000

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101080A BG62794B1 (bg) 1994-07-01 1996-12-28 Метод за получаване на лекарствена форма на карбамазепин съсзабавено освобождаване на активното вещество

Country Status (23)

Country Link
US (1) US5888545A (bg)
EP (1) EP0768882B1 (bg)
JP (1) JPH10502358A (bg)
KR (1) KR100344477B1 (bg)
CN (1) CN1101191C (bg)
AT (1) ATE169818T1 (bg)
BG (1) BG62794B1 (bg)
BR (1) BR9508202A (bg)
CA (1) CA2194216A1 (bg)
CZ (1) CZ288028B6 (bg)
DE (2) DE4423078B4 (bg)
DK (1) DK0768882T3 (bg)
EE (1) EE03954B1 (bg)
ES (1) ES2122630T3 (bg)
GE (1) GEP19991819B (bg)
HU (1) HU221486B (bg)
LT (1) LT4251B (bg)
LV (1) LV11820B (bg)
PL (1) PL180979B1 (bg)
RU (1) RU2141825C1 (bg)
SK (1) SK282303B6 (bg)
UA (1) UA32598C2 (bg)
WO (1) WO1996001112A1 (bg)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162466A (en) * 1999-04-15 2000-12-19 Taro Pharmaceutical Industries Ltd. Sustained release formulation of carbamazepine
US20060275367A1 (en) * 2005-04-25 2006-12-07 Shubha Chungi Extended release formulations
WO2007048219A2 (en) * 2005-09-09 2007-05-03 Labopharm Inc. Sustained drug release composition
US20070160960A1 (en) * 2005-10-21 2007-07-12 Laser Shot, Inc. System and method for calculating a projectile impact coordinates
FR2940910A1 (fr) * 2009-01-09 2010-07-16 Vetoquinol Sa Nouveau comprime a base de s-adenosyl-methionine
CN105997916A (zh) * 2016-07-19 2016-10-12 南京正宽医药科技有限公司 一种卡马西平片及其制备方法
CN108125922A (zh) * 2018-01-14 2018-06-08 上海安必生制药技术有限公司 一种卡马西平口服缓释制剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
SE8203953D0 (sv) * 1982-06-24 1982-06-24 Astra Laekemedel Ab Pharmaceutical mixture
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
CH668187A5 (de) * 1986-08-07 1988-12-15 Ciba Geigy Ag Therapeutisches system mit systemischer wirkung.
IL86211A (en) * 1987-05-04 1992-03-29 Ciba Geigy Ag Oral forms of administration for carbamazepine in the forms of stable aqueous suspension with delayed release and their preparation
US5326572A (en) * 1989-03-23 1994-07-05 Fmc Corporation Freeze-dried polymer dispersions and the use thereof in preparing sustained-release pharmaceutical compositions

Also Published As

Publication number Publication date
DK0768882T3 (da) 1999-05-25
US5888545A (en) 1999-03-30
KR970703774A (ko) 1997-08-09
LV11820B (en) 1997-12-20
GEP19991819B (en) 1999-11-05
LT4251B (en) 1997-12-29
CN1101191C (zh) 2003-02-12
WO1996001112A1 (de) 1996-01-18
PL317996A1 (en) 1997-05-12
DE4423078B4 (de) 2005-01-13
UA32598C2 (uk) 2001-02-15
DE4423078A1 (de) 1996-01-04
ES2122630T3 (es) 1998-12-16
PL180979B1 (pl) 2001-05-31
CN1153475A (zh) 1997-07-02
KR100344477B1 (ko) 2002-11-23
BG62794B1 (bg) 2000-08-31
EE03954B1 (et) 2003-02-17
EP0768882B1 (de) 1998-08-19
DE59503283D1 (de) 1998-09-24
EP0768882A1 (de) 1997-04-23
CA2194216A1 (en) 1996-01-18
BR9508202A (pt) 1997-11-11
LT97012A (en) 1997-08-25
EE9600202A (et) 1997-06-16
ATE169818T1 (de) 1998-09-15
HUT76821A (en) 1997-11-28
CZ288028B6 (cs) 2001-04-11
JPH10502358A (ja) 1998-03-03
SK282303B6 (sk) 2002-01-07
LV11820A (lv) 1997-08-20
HU221486B (en) 2002-10-28
SK164696A3 (en) 1997-06-04
CZ382696A3 (en) 1997-05-14
HU9603565D0 (en) 1997-02-28
RU2141825C1 (ru) 1999-11-27

Similar Documents

Publication Publication Date Title
PL304060A1 (en) Solid dosed form of prolonged release for oral administration and method of obtaining same,
HUP0200618A3 (en) Oral pharmaceutical pulsed release dosage form and process for its preparation
EP1078628A3 (en) Multiple unit tableted dosage form
AU8009998A (en) Method for producing orally administered, solid pharmaceutical products with controlled release of the active substance
IS4976A (is) 7a-(z-Amínóakýl)estratríen, aðferð til að búa þautil, lyfjasamsetningar sem innihalda fyrrnefnd 7a-(z-amínóakýl)estratríen og notkun þeirra í framleiðslu læknislyfja
HUP0100072A3 (en) Phenoxazine, phenthiazine derivatives, their use in medicine; process for their preparation and pharmaceutical compositions containing them
AT400295B (de) Orale feste pharmazeutische dosierungsform mit programmierter wirkstofffreisetzung und verfahren zu ihrer herstellung
ZA200110217B (en) Indole derivatives, process for their preparation, pharmaceutical compositions containing them and their medicinal application.
HUP9801044A3 (en) Sulfonylamino-carboxylic acid derivatives, process for their preparation, their use and pharmaceutical compositions containing them
HUP0105313A3 (en) Potassium salt of (s)-omeprazole, process for its preparation and pharmaceutical composition containing the same and its use
IL148870A0 (en) 2'-substituted 1, 1'-biphenyl-2-carbonamides, method for the production thereof, use thereof as medicament and pharmaceutical preparations containing said compounds
ZA966163B (en) Novel galanthamine derivatives, process for the preparation thereof, their application as medical drugs, and pharmaceutical compositions containing said derivatives.
AU1671799A (en) Medicament preparation in the form of a tablet or pellet for acid-labile active substances
BG101080A (bg) Метод за получаване на лекарствена форма на карбамазепин със забавено освобождаване на активното вещество
EP0654479A3 (en) Esculetin derivatives, process for their preparation and their use as pharmaceutical compositions.
HUP0201629A3 (en) Pharmaceutical complex containing eletriptan and cyclodextrin-derivative, pharmaceutical composition containing it, process for its preparation and its use
AU5520396A (en) Device and process for mixing a pharmaceutical composition with another agent and method for oral administration of the pharmaceutical preparation
HUP0200376A2 (en) Thiaoloindolinone compounds, process for their preparation and pharmaceutical composions containing them and their use
HU9302813D0 (en) Pharmaceutical compositions containing new benzimidazole derivatives and process for preparing the active ingredients
HUP0203161A3 (en) Benzamidine derivatives, process for their preparation and pharmaceutical compositions containing them and their use
HUP0003104A3 (en) Amino-spiropiperidin-quinazoline derivatives, their use, process for their preparation and pharmaceutical compositions containing them
HUP0002245A3 (en) Spiropiperidine derivatives, process for their preparation, their use and pharmaceutical compositions containing them
AU6308900A (en) Isoquinoline derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance
AU6037494A (en) Use of active substances in the therapy of certain diseases, process for preparing a pharmaceutical composition for that purpose and pharmaceutical compositions thus prepared
HUP9901458A3 (en) Crystal form ii. of tazofelone, process for preparation thereof, use and pharmaceutical composition containing the same