BG100289A - Ophthalmic solution based on diclofenac and tobramicine and its applications - Google Patents
Ophthalmic solution based on diclofenac and tobramicine and its applicationsInfo
- Publication number
- BG100289A BG100289A BG100289A BG10028996A BG100289A BG 100289 A BG100289 A BG 100289A BG 100289 A BG100289 A BG 100289A BG 10028996 A BG10028996 A BG 10028996A BG 100289 A BG100289 A BG 100289A
- Authority
- BG
- Bulgaria
- Prior art keywords
- tobramicine
- diclofenac
- applications
- solution based
- ophthalmic solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09401078A ES2079320B1 (es) | 1994-05-17 | 1994-05-17 | Disolucion oftalmica a base de un diclofenaco y tobramicina y sus aplicaciones. |
PCT/ES1994/000084 WO1995031179A1 (es) | 1994-05-17 | 1994-09-07 | Disolucion oftalmica a base de diclofenaco y tobramicina y sus aplicaciones |
Publications (1)
Publication Number | Publication Date |
---|---|
BG100289A true BG100289A (en) | 1996-12-31 |
Family
ID=8286285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG100289A BG100289A (en) | 1994-05-17 | 1996-01-17 | Ophthalmic solution based on diclofenac and tobramicine and its applications |
Country Status (21)
Country | Link |
---|---|
US (1) | US5597560A (no) |
EP (1) | EP0711546B1 (no) |
KR (1) | KR100353377B1 (no) |
CN (1) | CN1098678C (no) |
AT (1) | ATE198417T1 (no) |
AU (1) | AU696853B2 (no) |
BG (1) | BG100289A (no) |
BR (1) | BR9407330A (no) |
CA (1) | CA2167383C (no) |
DE (1) | DE69426529T2 (no) |
DK (1) | DK0711546T3 (no) |
ES (1) | ES2079320B1 (no) |
FI (1) | FI116884B (no) |
GR (1) | GR3035633T3 (no) |
HK (1) | HK1017806A1 (no) |
HU (1) | HUT74164A (no) |
NO (1) | NO308645B1 (no) |
OA (1) | OA10570A (no) |
PL (1) | PL312615A1 (no) |
PT (1) | PT711546E (no) |
WO (1) | WO1995031179A1 (no) |
Families Citing this family (85)
Publication number | Priority date | Publication date | Assignee | Title |
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DE19729879C2 (de) * | 1997-07-11 | 1999-07-08 | Mann Gerhard Chem Pharm Fab | Lagerstabile ophthalmische Zusammensetzungen, umfassend Diclofenac und Ofloxacin |
US6716830B2 (en) | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
US6395746B1 (en) | 1998-09-30 | 2002-05-28 | Alcon Manufacturing, Ltd. | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation |
US6509327B1 (en) | 1998-09-30 | 2003-01-21 | Alcon Manufacturing, Ltd. | Compositions and methods for treating otic, ophthalmic and nasal infections |
US7056893B2 (en) | 1999-03-31 | 2006-06-06 | Insite Vision, Inc. | Topical treatment for prevention of ocular infections |
US6239113B1 (en) | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
US8173164B2 (en) * | 1999-06-17 | 2012-05-08 | Gruenenthal Gmbh | Oral administration forms for administering a fixed tramadol and diclofenac combination |
US20020061281A1 (en) * | 1999-07-06 | 2002-05-23 | Osbakken Robert S. | Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis |
CN1371287A (zh) | 1999-07-22 | 2002-09-25 | 阿温蒂斯药物公司 | 防腐的药物制剂 |
US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
PL212457B1 (pl) | 2001-09-21 | 2012-10-31 | Alcon | Zastosowanie kombinacji ciprofloksacyny i deksametazonu |
US7928147B2 (en) * | 2002-04-11 | 2011-04-19 | Teva Animal Health, Inc. | Antimicrobial wash and carrier solutions, and uses thereof |
WO2004006957A1 (en) * | 2002-07-15 | 2004-01-22 | Alcon, Inc. | Pharmaceutical compositions for otic use |
IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
US20060193789A1 (en) * | 2002-10-25 | 2006-08-31 | Foamix Ltd. | Film forming foamable composition |
US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
AU2004266502B2 (en) * | 2002-10-25 | 2010-09-23 | Foamix Pharmaceuticals Ltd. | Penetrating pharmaceutical foam |
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US20070292359A1 (en) * | 2002-10-25 | 2007-12-20 | Foamix Ltd. | Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof |
US20080206161A1 (en) * | 2002-10-25 | 2008-08-28 | Dov Tamarkin | Quiescent foamable compositions, steroids, kits and uses thereof |
US20050186142A1 (en) * | 2002-10-25 | 2005-08-25 | Foamix Ltd. | Kit and composition of imidazole with enhanced bioavailability |
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WO2004056357A1 (en) * | 2002-12-20 | 2004-07-08 | Deepak Bahri | Composition comprising diclofenac for treating otic pain and inflammation |
WO2004064828A1 (ja) | 2003-01-21 | 2004-08-05 | Senju Pharmaceutical Co., Ltd. | 2−アミノ−3−(4−ブロモベンゾイル)フェニル酢酸含有水性液剤 |
US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
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US20050137164A1 (en) * | 2003-09-22 | 2005-06-23 | Moshe Arkin | Diclofenac compositions for the treatment of skin disorders |
CN100551378C (zh) * | 2003-11-14 | 2009-10-21 | 千寿制药株式会社 | 包含氨基糖苷类抗生素和溴芬酸的水溶液制剂 |
US8367086B1 (en) * | 2004-02-02 | 2013-02-05 | S.S. Steiner, Inc. | Process and product for inhibiting or preventing bacterial infections |
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US20050214382A1 (en) * | 2004-03-29 | 2005-09-29 | Erning Xia | Zinc preservative composition and method of use |
JP2005310310A (ja) * | 2004-04-23 | 2005-11-04 | Sanyo Electric Co Ltd | トラッキングバランス調整装置 |
US20060046970A1 (en) * | 2004-08-31 | 2006-03-02 | Insite Vision Incorporated | Topical otic compositions and methods of topical treatment of prevention of otic infections |
US20060073173A1 (en) * | 2004-10-04 | 2006-04-06 | Maria Banach | Large-scale manufacturing process for the production of pharmaceutical compositions |
WO2007070801A2 (en) * | 2005-12-12 | 2007-06-21 | Allaccem, Inc. | Methods and systems for preparing antimicrobial films and coatings |
CN1981869B (zh) * | 2005-12-14 | 2011-04-06 | 信谊药厂 | 含普拉洛芬的复方非载体抗菌眼用制剂及其制备方法 |
EP2049112B1 (en) * | 2006-08-07 | 2012-03-14 | Bausch & Lomb Incorporated | Treating infections and sequelae thereof with combined dissociated glucocorticoid receptor agonists and anti-infective agents |
US20080166303A1 (en) * | 2006-09-08 | 2008-07-10 | Dov Tamarkin | Colored or colorable foamable composition and foam |
US20080260655A1 (en) * | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
AU2007356328A1 (en) * | 2006-11-14 | 2009-01-15 | Tal Berman | Stable non-alcoholic foamable pharmaceutical emulsion compositions with an unctuous emollient and their uses |
WO2008085913A1 (en) * | 2007-01-04 | 2008-07-17 | Rib-X Pharmaceuticals, Inc. | Methods for treating, preventing, or reducing the risk of opthalmic, otic, and nasal infections |
US20080292560A1 (en) * | 2007-01-12 | 2008-11-27 | Dov Tamarkin | Silicone in glycol pharmaceutical and cosmetic compositions with accommodating agent |
DK2125026T3 (en) | 2007-02-21 | 2014-12-08 | Allaccem Inc | FORMATIONS BASED ON bridged POLYCYCLIC COMPOUNDS FOR INHIBITION AND RELIEF OF DISEASES |
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US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
US8153617B2 (en) * | 2007-08-10 | 2012-04-10 | Allaccem, Inc. | Bridged polycyclic compound based compositions for coating oral surfaces in humans |
US8188068B2 (en) * | 2007-08-10 | 2012-05-29 | Allaccem, Inc. | Bridged polycyclic compound based compositions for coating oral surfaces in pets |
US8153618B2 (en) * | 2007-08-10 | 2012-04-10 | Allaccem, Inc. | Bridged polycyclic compound based compositions for topical applications for pets |
US20090074833A1 (en) * | 2007-08-17 | 2009-03-19 | Whiteford Jeffery A | Bridged polycyclic compound based compositions for controlling bone resorption |
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US8871184B2 (en) | 2009-10-02 | 2014-10-28 | Foamix Ltd. | Topical tetracycline compositions |
US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
EP2498763A4 (en) | 2009-11-09 | 2015-10-07 | Spotlight Technology Partners Llc | HYDROGELS BASED ON POLYSACCHARIDE |
US8795727B2 (en) | 2009-11-09 | 2014-08-05 | Spotlight Technology Partners Llc | Fragmented hydrogels |
CN102526738B (zh) * | 2010-12-27 | 2016-03-30 | 沈阳兴齐眼药股份有限公司 | 一种复方眼用制剂、其制备方法和用途 |
CA2978573A1 (en) | 2016-09-08 | 2018-03-08 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
CN107865966A (zh) * | 2016-09-23 | 2018-04-03 | 刘力 | 局部给药的复方氨基糖苷类药物组合物 |
KR102283681B1 (ko) * | 2020-01-17 | 2021-07-29 | 조선대학교 산학협력단 | 렌즈 형상의 약물 전달 시스템 및 이의 제조 방법 |
EP4112041A1 (en) * | 2021-06-30 | 2023-01-04 | GSK Consumer Healthcare SARL | Micellar solution comprising diclofenac |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4087538A (en) * | 1976-09-09 | 1978-05-02 | Merck & Co., Inc. | Ophthalmic suspensions |
US4407792A (en) * | 1979-05-09 | 1983-10-04 | Alcon Laboratories, Inc. | Sustained release ophthalmic drug dosage |
NZ196700A (en) * | 1980-04-18 | 1983-04-12 | Smith & Nephew Ass | Anti-inflammatory compositions containing 5-benzoyl-1-methylpyrrole-2-acetic acid derivatives |
US4478822A (en) * | 1983-05-16 | 1984-10-23 | Merck & Co., Inc. | Drug delivery system utilizing thermosetting gels |
US4668506A (en) * | 1985-08-16 | 1987-05-26 | Bausch & Lomb Incorporated | Sustained-release formulation containing and amino acid polymer |
DE3612537C1 (de) * | 1986-04-14 | 1987-07-16 | Dispersa Ag | Arzneimittel zur Behandlung von Entzuendungen im Auge |
JPH0696542B2 (ja) * | 1987-09-11 | 1994-11-30 | シンテックス(ユー・エス・エイ)インコーポレイテッド | 眼用保存製剤およびその製法 |
US5414011A (en) * | 1987-09-11 | 1995-05-09 | Syntex (U.S.A.) Inc. | Preservative system for ophthalmic formulations |
WO1989009057A1 (en) * | 1988-03-09 | 1989-10-05 | Alcon Laboratories, Inc. | Combination of tobramycin and steroids for topical ophthalmic use |
ES2079994B1 (es) * | 1992-10-07 | 1996-08-01 | Cusi Lab | Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica. |
-
1994
- 1994-05-17 ES ES09401078A patent/ES2079320B1/es not_active Expired - Fee Related
- 1994-09-07 PL PL94312615A patent/PL312615A1/xx unknown
- 1994-09-07 HU HU9600095A patent/HUT74164A/hu unknown
- 1994-09-07 WO PCT/ES1994/000084 patent/WO1995031179A1/es active IP Right Grant
- 1994-09-07 KR KR1019960700285A patent/KR100353377B1/ko not_active IP Right Cessation
- 1994-09-07 EP EP94926248A patent/EP0711546B1/en not_active Expired - Lifetime
- 1994-09-07 PT PT94926248T patent/PT711546E/pt unknown
- 1994-09-07 BR BR9407330A patent/BR9407330A/pt not_active Application Discontinuation
- 1994-09-07 DK DK94926248T patent/DK0711546T3/da active
- 1994-09-07 CA CA002167383A patent/CA2167383C/en not_active Expired - Fee Related
- 1994-09-07 AU AU76160/94A patent/AU696853B2/en not_active Ceased
- 1994-09-07 CN CN94193294A patent/CN1098678C/zh not_active Expired - Fee Related
- 1994-09-07 DE DE69426529T patent/DE69426529T2/de not_active Expired - Fee Related
- 1994-09-07 AT AT94926248T patent/ATE198417T1/de not_active IP Right Cessation
-
1995
- 1995-04-10 US US08/419,387 patent/US5597560A/en not_active Expired - Lifetime
-
1996
- 1996-01-17 FI FI960232A patent/FI116884B/fi active IP Right Grant
- 1996-01-17 BG BG100289A patent/BG100289A/xx unknown
- 1996-01-17 NO NO960207A patent/NO308645B1/no not_active IP Right Cessation
- 1996-01-17 OA OA60766A patent/OA10570A/en unknown
-
1998
- 1998-12-11 HK HK98113200A patent/HK1017806A1/xx not_active IP Right Cessation
-
2001
- 2001-03-23 GR GR20010400478T patent/GR3035633T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2167383A1 (en) | 1995-11-23 |
DE69426529D1 (de) | 2001-02-08 |
KR100353377B1 (ko) | 2002-12-26 |
HUT74164A (en) | 1996-11-28 |
NO308645B1 (no) | 2000-10-09 |
WO1995031179A1 (es) | 1995-11-23 |
EP0711546B1 (en) | 2001-01-03 |
HK1017806A1 (en) | 1999-11-26 |
OA10570A (en) | 2002-06-20 |
CA2167383C (en) | 2001-11-20 |
PT711546E (pt) | 2001-06-29 |
FI116884B (fi) | 2006-03-31 |
KR960703581A (ko) | 1996-08-31 |
PL312615A1 (en) | 1996-04-29 |
ES2079320B1 (es) | 1996-10-16 |
CN1130351A (zh) | 1996-09-04 |
NO960207L (no) | 1996-03-15 |
EP0711546A1 (en) | 1996-05-15 |
CN1098678C (zh) | 2003-01-15 |
DK0711546T3 (da) | 2001-04-23 |
DE69426529T2 (de) | 2001-08-09 |
US5597560A (en) | 1997-01-28 |
BR9407330A (pt) | 1996-06-18 |
NO960207D0 (no) | 1996-01-17 |
ATE198417T1 (de) | 2001-01-15 |
AU696853B2 (en) | 1998-09-17 |
GR3035633T3 (en) | 2001-06-29 |
AU7616094A (en) | 1995-12-05 |
ES2079320A1 (es) | 1996-01-01 |
FI960232A (fi) | 1996-03-15 |
FI960232A0 (fi) | 1996-01-17 |
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