BE898856A - MITOMYCIN ANALOGS - Google Patents
MITOMYCIN ANALOGSInfo
- Publication number
- BE898856A BE898856A BE0/212351A BE212351A BE898856A BE 898856 A BE898856 A BE 898856A BE 0/212351 A BE0/212351 A BE 0/212351A BE 212351 A BE212351 A BE 212351A BE 898856 A BE898856 A BE 898856A
- Authority
- BE
- Belgium
- Prior art keywords
- mitomycin analogs
- mitomycin
- analogs
- azirino
- pyrrolo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Traitement d'affections néoplasiques au moyen de carbamate de 1, 1a, 2,8,8a,8b-hexahydro-8-(hydroxyméthyl)-8a-méthoxy-5-méthyl-6-(3-hydroxy-1-pyrrolidinyl)-azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione.Treatment of neoplastic conditions using carbamate of 1, 1a, 2,8,8a, 8b-hexahydro-8- (hydroxymethyl) -8a-methoxy-5-methyl-6- (3-hydroxy-1-pyrrolidinyl) - azirino (2 ', 3': 3,4) pyrrolo (1,2-a) indole-4,7-dione.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46461283A | 1983-02-07 | 1983-02-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE898856A true BE898856A (en) | 1984-05-30 |
Family
ID=23844605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/212351A BE898856A (en) | 1983-02-07 | 1984-02-07 | MITOMYCIN ANALOGS |
Country Status (29)
Country | Link |
---|---|
JP (1) | JPS59152384A (en) |
KR (1) | KR900006854B1 (en) |
AT (1) | AT385509B (en) |
AU (1) | AU571193B2 (en) |
BE (1) | BE898856A (en) |
CA (1) | CA1252789A (en) |
CH (1) | CH658658A5 (en) |
DD (1) | DD233844A5 (en) |
DE (1) | DE3403922A1 (en) |
DK (1) | DK161890C (en) |
ES (1) | ES8607305A1 (en) |
FI (1) | FI80698C (en) |
FR (1) | FR2540500B1 (en) |
GB (1) | GB2134514B (en) |
GR (1) | GR81455B (en) |
HU (1) | HU190236B (en) |
IE (1) | IE56814B1 (en) |
IL (1) | IL70897A (en) |
IT (1) | IT1178855B (en) |
LU (1) | LU85199A1 (en) |
NL (1) | NL8400338A (en) |
NO (1) | NO161374C (en) |
NZ (1) | NZ206932A (en) |
OA (1) | OA07654A (en) |
PH (1) | PH20249A (en) |
PT (1) | PT78067B (en) |
SE (1) | SE461982B (en) |
YU (1) | YU44984B (en) |
ZA (1) | ZA84788B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4487769A (en) * | 1982-06-04 | 1984-12-11 | Bristol-Myers Company | Amidines |
CA1282069C (en) * | 1985-09-12 | 1991-03-26 | Damon L. Meyer | Antibody complexes of hapten-modified diagnostic or therapeutic agents |
JPS63150282A (en) * | 1986-12-13 | 1988-06-22 | Kyowa Hakko Kogyo Co Ltd | Mitomycin derivative |
JPS63246379A (en) * | 1987-03-31 | 1988-10-13 | Kyowa Hakko Kogyo Co Ltd | 7-n,8-n-ethylenemitomycin 8-imines |
EP0485904B1 (en) * | 1990-11-13 | 1997-08-20 | Kyowa Hakko Kogyo Co., Ltd. | Mitomycin derivatives |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3332944A (en) * | 1964-11-02 | 1967-07-25 | American Cyanamid Co | Antibiotic derivatives of mitomycins a, b, c and porfiromycin |
JPS5439098A (en) * | 1977-08-31 | 1979-03-24 | Kyowa Hakko Kogyo Co Ltd | Mitomycin c derivatives |
US4268676A (en) * | 1979-12-05 | 1981-05-19 | University Patents, Inc. | Mitomycin analogs |
JPS5686184A (en) * | 1979-12-17 | 1981-07-13 | Kyowa Hakko Kogyo Co Ltd | Novel mitomycin c derivative |
NZ199617A (en) * | 1981-05-15 | 1985-08-30 | University Patents Inc | Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions |
US4487769A (en) * | 1982-06-04 | 1984-12-11 | Bristol-Myers Company | Amidines |
US4642352A (en) * | 1983-12-23 | 1987-02-10 | Bristol-Myers Company | Acylamino mitosanes |
-
1984
- 1984-01-25 NZ NZ206932A patent/NZ206932A/en unknown
- 1984-01-27 GB GB08402233A patent/GB2134514B/en not_active Expired
- 1984-02-02 ZA ZA84788A patent/ZA84788B/en unknown
- 1984-02-03 NL NL8400338A patent/NL8400338A/en not_active Application Discontinuation
- 1984-02-03 AU AU24073/84A patent/AU571193B2/en not_active Ceased
- 1984-02-04 DE DE19843403922 patent/DE3403922A1/en not_active Withdrawn
- 1984-02-06 DD DD84259885A patent/DD233844A5/en not_active IP Right Cessation
- 1984-02-06 GR GR73720A patent/GR81455B/el unknown
- 1984-02-06 PT PT78067A patent/PT78067B/en not_active IP Right Cessation
- 1984-02-06 IE IE272/84A patent/IE56814B1/en not_active IP Right Cessation
- 1984-02-06 CA CA000446811A patent/CA1252789A/en not_active Expired
- 1984-02-06 AT AT0037684A patent/AT385509B/en not_active IP Right Cessation
- 1984-02-06 ES ES529478A patent/ES8607305A1/en not_active Expired
- 1984-02-06 DK DK052484A patent/DK161890C/en active
- 1984-02-06 HU HU84483A patent/HU190236B/en not_active IP Right Cessation
- 1984-02-06 CH CH550/84A patent/CH658658A5/en not_active IP Right Cessation
- 1984-02-06 PH PH30204A patent/PH20249A/en unknown
- 1984-02-06 NO NO840433A patent/NO161374C/en unknown
- 1984-02-07 BE BE0/212351A patent/BE898856A/en not_active IP Right Cessation
- 1984-02-07 SE SE8400628A patent/SE461982B/en not_active IP Right Cessation
- 1984-02-07 KR KR1019840000574A patent/KR900006854B1/en not_active IP Right Cessation
- 1984-02-07 LU LU85199A patent/LU85199A1/en unknown
- 1984-02-07 FI FI840502A patent/FI80698C/en not_active IP Right Cessation
- 1984-02-07 FR FR8401845A patent/FR2540500B1/en not_active Expired
- 1984-02-07 IL IL70897A patent/IL70897A/en unknown
- 1984-02-07 OA OA58227A patent/OA07654A/en unknown
- 1984-02-07 JP JP59021505A patent/JPS59152384A/en active Pending
- 1984-02-07 IT IT67113/84A patent/IT1178855B/en active
- 1984-02-07 YU YU217/84A patent/YU44984B/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: UNIVERSITY PATENTS INC. Effective date: 19930228 |