BE872832A - Derives d'ammonium quaternaires a activite therapeutique - Google Patents

Derives d'ammonium quaternaires a activite therapeutique

Info

Publication number
BE872832A
BE872832A BE1009197A BE1009197A BE872832A BE 872832 A BE872832 A BE 872832A BE 1009197 A BE1009197 A BE 1009197A BE 1009197 A BE1009197 A BE 1009197A BE 872832 A BE872832 A BE 872832A
Authority
BE
Belgium
Prior art keywords
quaternary ammonium
therapeutic activity
ammonium derivatives
derivatives
therapeutic
Prior art date
Application number
BE1009197A
Other languages
English (en)
French (fr)
Inventor
B B Molloy
M I Steingerb
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE872832A publication Critical patent/BE872832A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/037—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements with quaternary ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE1009197A 1977-12-19 1978-12-18 Derives d'ammonium quaternaires a activite therapeutique BE872832A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86178977A 1977-12-19 1977-12-19

Publications (1)

Publication Number Publication Date
BE872832A true BE872832A (fr) 1979-06-18

Family

ID=25336767

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1009197A BE872832A (fr) 1977-12-19 1978-12-18 Derives d'ammonium quaternaires a activite therapeutique

Country Status (28)

Country Link
EP (1) EP0002604B1 (ko)
JP (1) JPS5495520A (ko)
AR (1) AR222813A1 (ko)
AT (1) AT363065B (ko)
AU (1) AU524727B2 (ko)
BE (1) BE872832A (ko)
CA (1) CA1093072A (ko)
CH (1) CH640506A5 (ko)
CS (1) CS857778A2 (ko)
DD (1) DD139842A5 (ko)
DE (1) DE2862243D1 (ko)
DK (1) DK150475C (ko)
EG (1) EG14601A (ko)
ES (1) ES476152A1 (ko)
FI (1) FI65425C (ko)
FR (1) FR2411824A1 (ko)
GB (1) GB2011388B (ko)
HU (1) HU178220B (ko)
IE (1) IE47693B1 (ko)
IL (1) IL56212A (ko)
LU (1) LU80670A1 (ko)
NZ (1) NZ189162A (ko)
PH (1) PH14394A (ko)
PT (1) PT68907A (ko)
RO (1) RO76881A2 (ko)
SU (1) SU745360A3 (ko)
YU (1) YU297578A (ko)
ZA (1) ZA787111B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336269A (en) 1979-12-10 1982-06-22 Eli Lilly And Company Para-nitrophenylalkylamines

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2952382A1 (de) * 1979-12-24 1981-07-16 Basf Ag, 6700 Ludwigshafen Phenylpropylammoniumsalze, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
DE3263407D1 (en) * 1981-08-29 1985-06-05 Basf Ag Fungicides containing phenylpropylammonium salt, and process for combating fungi
DE3421810A1 (de) * 1984-06-12 1985-12-12 Basf Ag, 6700 Ludwigshafen Phenylalkylamine - bioregulatoren
JPS61140547A (ja) * 1984-12-13 1986-06-27 Seitai Kagaku Kenkyusho:Kk フェネチルアミン誘導体および診断・治療剤
JPH02268142A (ja) * 1989-04-10 1990-11-01 Toubishi Yakuhin Kogyo Kk 筋弛緩作用を有する新規化合物及びその製造方法
WO2001008685A1 (en) * 1999-07-30 2001-02-08 Vertex Pharmaceuticals Incorporated Acyclic and cyclic amine derivatives
TWI356054B (en) * 2004-03-31 2012-01-11 Activus Pharma Co Ltd Quaternary ammonium compound, producing method the

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336269A (en) 1979-12-10 1982-06-22 Eli Lilly And Company Para-nitrophenylalkylamines

Also Published As

Publication number Publication date
ZA787111B (en) 1980-08-27
IE47693B1 (en) 1984-05-30
RO76881A2 (ro) 1981-08-30
DK150475C (da) 1987-10-26
GB2011388B (en) 1982-04-28
ES476152A1 (es) 1980-05-16
CA1093072A (en) 1981-01-06
DE2862243D1 (en) 1983-06-09
CS857778A2 (en) 1985-07-16
PH14394A (en) 1981-06-25
AR222813A1 (es) 1981-06-30
DK567778A (da) 1979-07-31
YU297578A (en) 1982-10-31
PT68907A (en) 1979-01-01
HU178220B (en) 1982-03-28
EP0002604A1 (en) 1979-06-27
GB2011388A (en) 1979-07-11
IL56212A0 (en) 1979-03-12
JPS5495520A (en) 1979-07-28
DK150475B (da) 1987-03-09
FI783845A (fi) 1979-06-20
FI65425C (fi) 1984-05-10
IL56212A (en) 1982-08-31
NZ189162A (en) 1980-10-24
DD139842A5 (de) 1980-01-23
EP0002604B1 (en) 1983-05-04
FI65425B (fi) 1984-01-31
FR2411824B1 (ko) 1985-03-29
JPS6214538B2 (ko) 1987-04-02
SU745360A3 (ru) 1980-06-30
EG14601A (en) 1984-09-30
ATA904378A (de) 1980-12-15
AU524727B2 (en) 1982-09-30
CH640506A5 (fr) 1984-01-13
LU80670A1 (fr) 1979-04-13
IE782489L (en) 1979-06-19
AU4255478A (en) 1979-06-28
AT363065B (de) 1981-07-10
FR2411824A1 (fr) 1979-07-13

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19951231