FI65425B - Foerfarande foer framstaellning av ett terapeutiskt anvaendbart kvaternaert ammoniumsalt av fenylalkylamin - Google Patents

Foerfarande foer framstaellning av ett terapeutiskt anvaendbart kvaternaert ammoniumsalt av fenylalkylamin

Info

Publication number
FI65425B
FI65425B FI783845A FI783845A FI65425B FI 65425 B FI65425 B FI 65425B FI 783845 A FI783845 A FI 783845A FI 783845 A FI783845 A FI 783845A FI 65425 B FI65425 B FI 65425B
Authority
FI
Finland
Prior art keywords
phenylalkylamine
eth
framework
procedure
ammonium salt
Prior art date
Application number
FI783845A
Other languages
English (en)
Other versions
FI783845A (fi
FI65425C (fi
Inventor
Bryan Barnet Molloy
Mitchell Irvin Steinberg
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI783845A publication Critical patent/FI783845A/fi
Publication of FI65425B publication Critical patent/FI65425B/fi
Application granted granted Critical
Publication of FI65425C publication Critical patent/FI65425C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/037—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements with quaternary ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI783845A 1977-12-19 1978-12-14 Foerfarande foer framstaellning av ett terapeutiskt anvaendbart kvaternaert ammoniumsalt av fenylalkylamin FI65425C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86178977A 1977-12-19 1977-12-19
US86178977 1977-12-19

Publications (3)

Publication Number Publication Date
FI783845A FI783845A (fi) 1979-06-20
FI65425B true FI65425B (fi) 1984-01-31
FI65425C FI65425C (fi) 1984-05-10

Family

ID=25336767

Family Applications (1)

Application Number Title Priority Date Filing Date
FI783845A FI65425C (fi) 1977-12-19 1978-12-14 Foerfarande foer framstaellning av ett terapeutiskt anvaendbart kvaternaert ammoniumsalt av fenylalkylamin

Country Status (28)

Country Link
EP (1) EP0002604B1 (fi)
JP (1) JPS5495520A (fi)
AR (1) AR222813A1 (fi)
AT (1) AT363065B (fi)
AU (1) AU524727B2 (fi)
BE (1) BE872832A (fi)
CA (1) CA1093072A (fi)
CH (1) CH640506A5 (fi)
CS (1) CS857778A2 (fi)
DD (1) DD139842A5 (fi)
DE (1) DE2862243D1 (fi)
DK (1) DK150475C (fi)
EG (1) EG14601A (fi)
ES (1) ES476152A1 (fi)
FI (1) FI65425C (fi)
FR (1) FR2411824A1 (fi)
GB (1) GB2011388B (fi)
HU (1) HU178220B (fi)
IE (1) IE47693B1 (fi)
IL (1) IL56212A (fi)
LU (1) LU80670A1 (fi)
NZ (1) NZ189162A (fi)
PH (1) PH14394A (fi)
PT (1) PT68907A (fi)
RO (1) RO76881A2 (fi)
SU (1) SU745360A3 (fi)
YU (1) YU297578A (fi)
ZA (1) ZA787111B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336269A (en) 1979-12-10 1982-06-22 Eli Lilly And Company Para-nitrophenylalkylamines
DE2952382A1 (de) * 1979-12-24 1981-07-16 Basf Ag, 6700 Ludwigshafen Phenylpropylammoniumsalze, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
DE3263407D1 (en) * 1981-08-29 1985-06-05 Basf Ag Fungicides containing phenylpropylammonium salt, and process for combating fungi
DE3421810A1 (de) * 1984-06-12 1985-12-12 Basf Ag, 6700 Ludwigshafen Phenylalkylamine - bioregulatoren
JPS61140547A (ja) * 1984-12-13 1986-06-27 Seitai Kagaku Kenkyusho:Kk フェネチルアミン誘導体および診断・治療剤
JPH02268142A (ja) * 1989-04-10 1990-11-01 Toubishi Yakuhin Kogyo Kk 筋弛緩作用を有する新規化合物及びその製造方法
WO2001008685A1 (en) * 1999-07-30 2001-02-08 Vertex Pharmaceuticals Incorporated Acyclic and cyclic amine derivatives
TWI356054B (en) * 2004-03-31 2012-01-11 Activus Pharma Co Ltd Quaternary ammonium compound, producing method the

Also Published As

Publication number Publication date
IL56212A (en) 1982-08-31
ES476152A1 (es) 1980-05-16
JPS6214538B2 (fi) 1987-04-02
CH640506A5 (fr) 1984-01-13
GB2011388A (en) 1979-07-11
AU4255478A (en) 1979-06-28
HU178220B (en) 1982-03-28
CS857778A2 (en) 1985-07-16
EG14601A (en) 1984-09-30
YU297578A (en) 1982-10-31
FI783845A (fi) 1979-06-20
ZA787111B (en) 1980-08-27
IE782489L (en) 1979-06-19
ATA904378A (de) 1980-12-15
LU80670A1 (fr) 1979-04-13
CA1093072A (en) 1981-01-06
DD139842A5 (de) 1980-01-23
DK150475C (da) 1987-10-26
RO76881A2 (ro) 1981-08-30
SU745360A3 (ru) 1980-06-30
FR2411824B1 (fi) 1985-03-29
AU524727B2 (en) 1982-09-30
DK567778A (da) 1979-07-31
DE2862243D1 (en) 1983-06-09
EP0002604B1 (en) 1983-05-04
PH14394A (en) 1981-06-25
EP0002604A1 (en) 1979-06-27
AT363065B (de) 1981-07-10
NZ189162A (en) 1980-10-24
AR222813A1 (es) 1981-06-30
FI65425C (fi) 1984-05-10
IE47693B1 (en) 1984-05-30
DK150475B (da) 1987-03-09
FR2411824A1 (fr) 1979-07-13
IL56212A0 (en) 1979-03-12
GB2011388B (en) 1982-04-28
PT68907A (en) 1979-01-01
BE872832A (fr) 1979-06-18
JPS5495520A (en) 1979-07-28

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed
MM Patent lapsed

Owner name: ELI LILLY AND CO