BE860126A - Derives de 4,6-di-o-(aminoglycosyl)-1,3-diamino-cyclitols leur procede de preparation et compositions pharmaceutiques les contenant - Google Patents

Derives de 4,6-di-o-(aminoglycosyl)-1,3-diamino-cyclitols leur procede de preparation et compositions pharmaceutiques les contenant

Info

Publication number
BE860126A
BE860126A BE182073A BE182073A BE860126A BE 860126 A BE860126 A BE 860126A BE 182073 A BE182073 A BE 182073A BE 182073 A BE182073 A BE 182073A BE 860126 A BE860126 A BE 860126A
Authority
BE
Belgium
Prior art keywords
aminoglycosyl
cyclitols
diamino
derivatives
pharmaceutical compositions
Prior art date
Application number
BE182073A
Other languages
English (en)
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of BE860126A publication Critical patent/BE860126A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/20—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hydrogen atoms and substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE182073A 1976-10-28 1977-10-26 Derives de 4,6-di-o-(aminoglycosyl)-1,3-diamino-cyclitols leur procede de preparation et compositions pharmaceutiques les contenant BE860126A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/736,640 US4171356A (en) 1976-10-28 1976-10-28 2-Unsubstituted derivatives of 4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitois, methods for their use as antibacterial agents and compositions useful therefor

Publications (1)

Publication Number Publication Date
BE860126A true BE860126A (fr) 1978-04-26

Family

ID=24960674

Family Applications (1)

Application Number Title Priority Date Filing Date
BE182073A BE860126A (fr) 1976-10-28 1977-10-26 Derives de 4,6-di-o-(aminoglycosyl)-1,3-diamino-cyclitols leur procede de preparation et compositions pharmaceutiques les contenant

Country Status (6)

Country Link
US (1) US4171356A (fr)
JP (1) JPS5356607A (fr)
BE (1) BE860126A (fr)
DE (1) DE2747946A1 (fr)
FR (1) FR2369293A1 (fr)
GB (1) GB1577540A (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5815994A (ja) * 1981-07-22 1983-01-29 Microbial Chem Res Found ２′位修飾カナマイシン誘導体およびその製造法
JPS58164600A (ja) * 1982-03-09 1983-09-29 Microbial Chem Res Found ３″−デオキシストレプトマイシン
JPS58154597A (ja) * 1982-03-10 1983-09-14 Microbial Chem Res Found ３″−エピストレプトマイシン又はそのジヒドロ体
JPS5953498A (ja) * 1982-09-20 1984-03-28 Microbial Chem Res Found ５，２′，３′，４′，４″，６″−ヘキサデオキシカナマイシンおよびその１−ｎ−アシル誘導体
JPS6041692A (ja) * 1983-08-15 1985-03-05 Microbial Chem Res Found ２′，３′−ジデオキシカナマイシンａ誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920628A (en) * 1972-10-24 1975-11-18 Schering Corp 2{41 -Deoxyaminoglycosides and 2{41 -epi-amino-3{41 -desamino derivatives thereof, methods for their manufacture and novel intermediates useful therein
CH606434A5 (fr) * 1973-08-06 1978-10-31 Scherico Ltd
ZA757397B (en) * 1974-11-29 1976-10-27 Scherico Ltd Pseudotrisaccharides and methods for their production
US3985727A (en) * 1975-03-28 1976-10-12 Schering Corporation Aminoglycoside antibiotics
US4208531A (en) * 1976-06-10 1980-06-17 Canas Rodriquez Antonio Synthetic aminoglycosides

Also Published As

Publication number Publication date
US4171356A (en) 1979-10-16
DE2747946A1 (de) 1978-05-11
JPS5356607A (en) 1978-05-23
FR2369293A1 (fr) 1978-05-26
GB1577540A (en) 1980-10-22

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