BE849379A - Nouvelles pyrazinecarboxamides utiles comme medicaments et procedes permettant de les preparer - Google Patents

Nouvelles pyrazinecarboxamides utiles comme medicaments et procedes permettant de les preparer

Info

Publication number
BE849379A
BE849379A BE173235A BE173235A BE849379A BE 849379 A BE849379 A BE 849379A BE 173235 A BE173235 A BE 173235A BE 173235 A BE173235 A BE 173235A BE 849379 A BE849379 A BE 849379A
Authority
BE
Belgium
Prior art keywords
pyrazinecarboxamides
preparing
useful
new
methods
Prior art date
Application number
BE173235A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE849379A publication Critical patent/BE849379A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE173235A 1975-12-15 1976-12-14 Nouvelles pyrazinecarboxamides utiles comme medicaments et procedes permettant de les preparer BE849379A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64080375A 1975-12-15 1975-12-15

Publications (1)

Publication Number Publication Date
BE849379A true BE849379A (fr) 1977-06-14

Family

ID=24569755

Family Applications (1)

Application Number Title Priority Date Filing Date
BE173235A BE849379A (fr) 1975-12-15 1976-12-14 Nouvelles pyrazinecarboxamides utiles comme medicaments et procedes permettant de les preparer

Country Status (14)

Country Link
US (1) US4085211A (fr)
JP (1) JPS52106877A (fr)
AU (1) AU511429B2 (fr)
BE (1) BE849379A (fr)
CH (1) CH630369A5 (fr)
DE (1) DE2656374A1 (fr)
DK (1) DK531476A (fr)
ES (2) ES454160A1 (fr)
FR (1) FR2335226A1 (fr)
GB (1) GB1527297A (fr)
HU (1) HU175504B (fr)
NL (1) NL7613276A (fr)
SE (1) SE431452B (fr)
ZA (1) ZA767431B (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208413A (en) * 1977-03-04 1980-06-17 Merck & Co., Inc. N-Pyrazinecarbonyl-N'-alkoxycarbonyl and N',N"-bis(alkoxycarbonyl)guanidines and processes for preparing same
US4163781A (en) * 1978-04-17 1979-08-07 Merck & Co., Inc. 3-Amino-N-[(phosphonoamino)iminomethyl]-6-halopyrazinecarboxamide compounds, compositions and methods of use
EP0009054A1 (fr) * 1978-09-19 1980-04-02 Merck & Co. Inc. N-Pyrazinecarbonyl-sulfamoylguanidines substituées en N' et procédés pour leur préparation
US4272537A (en) * 1980-07-02 1981-06-09 Merck & Co., Inc. 3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides
US4277602A (en) * 1980-07-02 1981-07-07 Merck & Co., Inc. 3-Amino-5-substituted-6-halo-N-(3,4-dihydro-6-substituted-1,3,5-truazin-2-yl)2-pyrazinecarboxamides
FI820266L (fi) * 1981-02-02 1982-08-03 Ici Plc Alkanolaminderivater
US4594349A (en) * 1982-01-04 1986-06-10 Beyer Jr Karl H Hyperuretic agents
JPS62291361A (ja) * 1986-06-09 1987-12-18 株式会社ブリヂストン 床支持装置
JPS6342741U (fr) * 1986-09-04 1988-03-22
GB8810933D0 (en) * 1987-05-26 1988-06-15 Ici America Inc Heterocyclic compounds
GB8810934D0 (en) * 1987-05-26 1988-06-15 Ici America Inc Amides
GB8812342D0 (en) * 1988-05-25 1988-06-29 Ici America Inc Bicyclic compounds
GB8812343D0 (en) * 1988-05-25 1988-06-29 Ici America Inc Amino compounds
JPH02101937U (fr) * 1989-01-31 1990-08-14
AUPP646498A0 (en) * 1998-10-12 1998-11-05 Australian National University, The A method of modulating ion channel functional activity
US6858614B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenolic guanidine sodium channel blockers
US6858615B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20050090505A1 (en) * 2003-08-18 2005-04-28 Johnson Michael R. Methods of reducing risk of infection from pathogens
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
US20090253714A1 (en) * 2003-08-20 2009-10-08 Johnson Michael R Methods of reducing risk of infection from pathogens
WO2006023617A2 (fr) * 2004-08-18 2006-03-02 Johnson Michael R Bloqueurs des canaux sodiques a base d'amide cyclique et d'ester pyrazinoylguanidine
US20070021439A1 (en) * 2005-07-25 2007-01-25 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers
GB0526244D0 (en) * 2005-12-22 2006-02-01 Novartis Ag Organic compounds
AR069637A1 (es) 2007-12-10 2010-02-10 Novartis Ag Derivados de pirazinas
DE102008053024B4 (de) 2008-10-24 2015-04-30 RUHR-UNIVERSITäT BOCHUM Verwendung von Amilorid-Derivaten zur Bekämpfung von Insekten und Milben
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
BR112015014178A2 (pt) 2012-12-17 2017-07-11 Parion Sciences Inc compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida
ES2619954T3 (es) 2012-12-17 2017-06-27 Parion Sciences, Inc. Derivados de cloropiracinocarboxamida útiles para el tratamiento de enfermedades favorecidas por una hidratación mucosa insuficiente
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
WO2016043230A1 (fr) * 2014-09-18 2016-03-24 日産化学工業株式会社 Agent d'alignement de cristaux liquides, film d'alignement de cristaux liquides, et élément d'affichage à cristaux liquides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL299931A (fr) * 1962-10-30
NL299929A (fr) * 1962-10-30

Also Published As

Publication number Publication date
SE431452B (sv) 1984-02-06
ES454160A1 (es) 1978-03-01
DK531476A (da) 1977-06-16
ES465742A1 (es) 1978-10-01
FR2335226A1 (fr) 1977-07-15
GB1527297A (en) 1978-10-04
DE2656374C2 (fr) 1989-08-10
CH630369A5 (de) 1982-06-15
AU2018176A (en) 1978-06-08
NL7613276A (nl) 1977-06-17
US4085211A (en) 1978-04-18
FR2335226B1 (fr) 1979-03-09
ZA767431B (en) 1978-07-26
HU175504B (hu) 1980-08-28
JPS6238350B2 (fr) 1987-08-17
AU511429B2 (en) 1980-08-21
SE7613289L (sv) 1977-06-16
DE2656374A1 (de) 1977-06-16
JPS52106877A (en) 1977-09-07

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: MERCK & CO. INC.

Effective date: 19891231