JPS52106877A - Novel pyridinecarboxyamides and their preparation - Google Patents

Novel pyridinecarboxyamides and their preparation

Info

Publication number
JPS52106877A
JPS52106877A JP14988976A JP14988976A JPS52106877A JP S52106877 A JPS52106877 A JP S52106877A JP 14988976 A JP14988976 A JP 14988976A JP 14988976 A JP14988976 A JP 14988976A JP S52106877 A JPS52106877 A JP S52106877A
Authority
JP
Japan
Prior art keywords
pyridinecarboxyamides
novel
preparation
novel pyridinecarboxyamides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14988976A
Other languages
English (en)
Other versions
JPS6238350B2 (ja
Inventor
Jiee Kuragoo Jiyuniya Edowaado
Daburiyu Uorutaasudoru Otsutoo
Enu Habetsukaa Chiyaarusu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS52106877A publication Critical patent/JPS52106877A/ja
Publication of JPS6238350B2 publication Critical patent/JPS6238350B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP14988976A 1975-12-15 1976-12-15 Novel pyridinecarboxyamides and their preparation Granted JPS52106877A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64080375A 1975-12-15 1975-12-15

Publications (2)

Publication Number Publication Date
JPS52106877A true JPS52106877A (en) 1977-09-07
JPS6238350B2 JPS6238350B2 (ja) 1987-08-17

Family

ID=24569755

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14988976A Granted JPS52106877A (en) 1975-12-15 1976-12-15 Novel pyridinecarboxyamides and their preparation

Country Status (14)

Country Link
US (1) US4085211A (ja)
JP (1) JPS52106877A (ja)
AU (1) AU511429B2 (ja)
BE (1) BE849379A (ja)
CH (1) CH630369A5 (ja)
DE (1) DE2656374A1 (ja)
DK (1) DK531476A (ja)
ES (2) ES454160A1 (ja)
FR (1) FR2335226A1 (ja)
GB (1) GB1527297A (ja)
HU (1) HU175504B (ja)
NL (1) NL7613276A (ja)
SE (1) SE431452B (ja)
ZA (1) ZA767431B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011506386A (ja) * 2007-12-10 2011-03-03 ノバルティス アーゲー 有機化合物
WO2016043230A1 (ja) * 2014-09-18 2016-03-24 日産化学工業株式会社 液晶配向剤、液晶配向膜、及び液晶表示素子

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208413A (en) * 1977-03-04 1980-06-17 Merck & Co., Inc. N-Pyrazinecarbonyl-N'-alkoxycarbonyl and N',N"-bis(alkoxycarbonyl)guanidines and processes for preparing same
US4163781A (en) * 1978-04-17 1979-08-07 Merck & Co., Inc. 3-Amino-N-[(phosphonoamino)iminomethyl]-6-halopyrazinecarboxamide compounds, compositions and methods of use
EP0009054A1 (en) * 1978-09-19 1980-04-02 Merck & Co. Inc. N-Pyrazinecarbonyl-N'-substituted-sulfamoyl-guanidine and processes for preparing same
US4277602A (en) * 1980-07-02 1981-07-07 Merck & Co., Inc. 3-Amino-5-substituted-6-halo-N-(3,4-dihydro-6-substituted-1,3,5-truazin-2-yl)2-pyrazinecarboxamides
US4272537A (en) * 1980-07-02 1981-06-09 Merck & Co., Inc. 3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides
FI820266L (fi) * 1981-02-02 1982-08-03 Ici Plc Alkanolaminderivater
US4594349A (en) * 1982-01-04 1986-06-10 Beyer Jr Karl H Hyperuretic agents
JPS62291361A (ja) * 1986-06-09 1987-12-18 株式会社ブリヂストン 床支持装置
JPS6342741U (ja) * 1986-09-04 1988-03-22
GB8810933D0 (en) * 1987-05-26 1988-06-15 Ici America Inc Heterocyclic compounds
GB8810934D0 (en) * 1987-05-26 1988-06-15 Ici America Inc Amides
GB8812343D0 (en) * 1988-05-25 1988-06-29 Ici America Inc Amino compounds
GB8812342D0 (en) * 1988-05-25 1988-06-29 Ici America Inc Bicyclic compounds
JPH02101937U (ja) * 1989-01-31 1990-08-14
AUPP646498A0 (en) * 1998-10-12 1998-11-05 Australian National University, The A method of modulating ion channel functional activity
US6858615B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6858614B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenolic guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20050090505A1 (en) * 2003-08-18 2005-04-28 Johnson Michael R. Methods of reducing risk of infection from pathogens
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
US20090253714A1 (en) * 2003-08-20 2009-10-08 Johnson Michael R Methods of reducing risk of infection from pathogens
WO2006023617A2 (en) * 2004-08-18 2006-03-02 Johnson Michael R Cyclic amide & ester pyrazinoylguanidine sodium channel blockers
US20070021439A1 (en) * 2005-07-25 2007-01-25 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers
GB0526244D0 (en) * 2005-12-22 2006-02-01 Novartis Ag Organic compounds
DE102008053024B4 (de) 2008-10-24 2015-04-30 RUHR-UNIVERSITäT BOCHUM Verwendung von Amilorid-Derivaten zur Bekämpfung von Insekten und Milben
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
PT2931713T (pt) 2012-12-17 2017-02-22 Parion Sciences Inc Derivados de cloro-pirazina carboxamida úteis para o tratamento de doenças favorecidas por insuficiente hidratação das mucosas
BR112015014178A2 (pt) 2012-12-17 2017-07-11 Parion Sciences Inc compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE639386A (ja) * 1962-10-30
NL299929A (ja) * 1962-10-30

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011506386A (ja) * 2007-12-10 2011-03-03 ノバルティス アーゲー 有機化合物
WO2016043230A1 (ja) * 2014-09-18 2016-03-24 日産化学工業株式会社 液晶配向剤、液晶配向膜、及び液晶表示素子

Also Published As

Publication number Publication date
BE849379A (fr) 1977-06-14
ES465742A1 (es) 1978-10-01
DE2656374C2 (ja) 1989-08-10
FR2335226B1 (ja) 1979-03-09
AU2018176A (en) 1978-06-08
SE7613289L (sv) 1977-06-16
AU511429B2 (en) 1980-08-21
SE431452B (sv) 1984-02-06
NL7613276A (nl) 1977-06-17
GB1527297A (en) 1978-10-04
HU175504B (hu) 1980-08-28
ZA767431B (en) 1978-07-26
DE2656374A1 (de) 1977-06-16
FR2335226A1 (fr) 1977-07-15
JPS6238350B2 (ja) 1987-08-17
CH630369A5 (de) 1982-06-15
ES454160A1 (es) 1978-03-01
US4085211A (en) 1978-04-18
DK531476A (da) 1977-06-16

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