DK531476A - Fremgangsmade til fremstilling af pyrazincarboxamid-forbindelser - Google Patents
Fremgangsmade til fremstilling af pyrazincarboxamid-forbindelserInfo
- Publication number
- DK531476A DK531476A DK531476A DK531476A DK531476A DK 531476 A DK531476 A DK 531476A DK 531476 A DK531476 A DK 531476A DK 531476 A DK531476 A DK 531476A DK 531476 A DK531476 A DK 531476A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- preparation
- carboxamide compounds
- pyrazine carboxamide
- pyrazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64080375A | 1975-12-15 | 1975-12-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK531476A true DK531476A (da) | 1977-06-16 |
Family
ID=24569755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK531476A DK531476A (da) | 1975-12-15 | 1976-11-25 | Fremgangsmade til fremstilling af pyrazincarboxamid-forbindelser |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4085211A (da) |
| JP (1) | JPS52106877A (da) |
| AU (1) | AU511429B2 (da) |
| BE (1) | BE849379A (da) |
| CH (1) | CH630369A5 (da) |
| DE (1) | DE2656374A1 (da) |
| DK (1) | DK531476A (da) |
| ES (2) | ES454160A1 (da) |
| FR (1) | FR2335226A1 (da) |
| GB (1) | GB1527297A (da) |
| HU (1) | HU175504B (da) |
| NL (1) | NL7613276A (da) |
| SE (1) | SE431452B (da) |
| ZA (1) | ZA767431B (da) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4208413A (en) * | 1977-03-04 | 1980-06-17 | Merck & Co., Inc. | N-Pyrazinecarbonyl-N'-alkoxycarbonyl and N',N"-bis(alkoxycarbonyl)guanidines and processes for preparing same |
| US4163781A (en) * | 1978-04-17 | 1979-08-07 | Merck & Co., Inc. | 3-Amino-N-[(phosphonoamino)iminomethyl]-6-halopyrazinecarboxamide compounds, compositions and methods of use |
| EP0009054A1 (en) * | 1978-09-19 | 1980-04-02 | Merck & Co. Inc. | N-Pyrazinecarbonyl-N'-substituted-sulfamoyl-guanidine and processes for preparing same |
| US4277602A (en) * | 1980-07-02 | 1981-07-07 | Merck & Co., Inc. | 3-Amino-5-substituted-6-halo-N-(3,4-dihydro-6-substituted-1,3,5-truazin-2-yl)2-pyrazinecarboxamides |
| US4272537A (en) * | 1980-07-02 | 1981-06-09 | Merck & Co., Inc. | 3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides |
| FI820266L (fi) * | 1981-02-02 | 1982-08-03 | Ici Plc | Alkanolaminderivater |
| US4594349A (en) * | 1982-01-04 | 1986-06-10 | Beyer Jr Karl H | Hyperuretic agents |
| JPS62291361A (ja) * | 1986-06-09 | 1987-12-18 | 株式会社ブリヂストン | 床支持装置 |
| JPS6342741U (da) * | 1986-09-04 | 1988-03-22 | ||
| GB8810933D0 (en) * | 1987-05-26 | 1988-06-15 | Ici America Inc | Heterocyclic compounds |
| GB8810934D0 (en) * | 1987-05-26 | 1988-06-15 | Ici America Inc | Amides |
| GB8812343D0 (en) * | 1988-05-25 | 1988-06-29 | Ici America Inc | Amino compounds |
| GB8812342D0 (en) * | 1988-05-25 | 1988-06-29 | Ici America Inc | Bicyclic compounds |
| JPH02101937U (da) * | 1989-01-31 | 1990-08-14 | ||
| AUPP646498A0 (en) * | 1998-10-12 | 1998-11-05 | Australian National University, The | A method of modulating ion channel functional activity |
| US6858615B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6858614B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenolic guanidine sodium channel blockers |
| US6903105B2 (en) * | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US20050090505A1 (en) * | 2003-08-18 | 2005-04-28 | Johnson Michael R. | Methods of reducing risk of infection from pathogens |
| US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| US20090253714A1 (en) * | 2003-08-20 | 2009-10-08 | Johnson Michael R | Methods of reducing risk of infection from pathogens |
| WO2006023617A2 (en) * | 2004-08-18 | 2006-03-02 | Johnson Michael R | Cyclic amide & ester pyrazinoylguanidine sodium channel blockers |
| US20070021439A1 (en) * | 2005-07-25 | 2007-01-25 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers |
| GB0526244D0 (en) * | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
| KR101578235B1 (ko) | 2007-12-10 | 2015-12-16 | 노파르티스 아게 | 유기 화합물 |
| DE102008053024B4 (de) | 2008-10-24 | 2015-04-30 | RUHR-UNIVERSITäT BOCHUM | Verwendung von Amilorid-Derivaten zur Bekämpfung von Insekten und Milben |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| PT2931713T (pt) | 2012-12-17 | 2017-02-22 | Parion Sciences Inc | Derivados de cloro-pirazina carboxamida úteis para o tratamento de doenças favorecidas por insuficiente hidratação das mucosas |
| BR112015014178A2 (pt) | 2012-12-17 | 2017-07-11 | Parion Sciences Inc | compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
| CN107003568B (zh) * | 2014-09-18 | 2020-09-15 | 日产化学工业株式会社 | 液晶取向剂、液晶取向膜和液晶表示元件 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE639386A (da) * | 1962-10-30 | |||
| NL299929A (da) * | 1962-10-30 |
-
1976
- 1976-09-13 US US05/722,442 patent/US4085211A/en not_active Expired - Lifetime
- 1976-11-25 DK DK531476A patent/DK531476A/da not_active Application Discontinuation
- 1976-11-26 SE SE7613289A patent/SE431452B/xx not_active IP Right Cessation
- 1976-11-29 NL NL7613276A patent/NL7613276A/xx not_active Application Discontinuation
- 1976-12-02 AU AU20181/76A patent/AU511429B2/en not_active Expired
- 1976-12-10 ES ES454160A patent/ES454160A1/es not_active Expired
- 1976-12-13 GB GB51940/76A patent/GB1527297A/en not_active Expired
- 1976-12-13 FR FR7637459A patent/FR2335226A1/fr active Granted
- 1976-12-13 DE DE19762656374 patent/DE2656374A1/de active Granted
- 1976-12-13 HU HU76ME2034A patent/HU175504B/hu unknown
- 1976-12-13 CH CH1566076A patent/CH630369A5/de not_active IP Right Cessation
- 1976-12-14 BE BE173235A patent/BE849379A/xx not_active IP Right Cessation
- 1976-12-14 ZA ZA00767431A patent/ZA767431B/xx unknown
- 1976-12-15 JP JP14988976A patent/JPS52106877A/ja active Granted
-
1978
- 1978-01-03 ES ES465742A patent/ES465742A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE849379A (fr) | 1977-06-14 |
| ES465742A1 (es) | 1978-10-01 |
| DE2656374C2 (da) | 1989-08-10 |
| FR2335226B1 (da) | 1979-03-09 |
| AU2018176A (en) | 1978-06-08 |
| SE7613289L (sv) | 1977-06-16 |
| AU511429B2 (en) | 1980-08-21 |
| SE431452B (sv) | 1984-02-06 |
| NL7613276A (nl) | 1977-06-17 |
| GB1527297A (en) | 1978-10-04 |
| HU175504B (hu) | 1980-08-28 |
| ZA767431B (en) | 1978-07-26 |
| DE2656374A1 (de) | 1977-06-16 |
| FR2335226A1 (fr) | 1977-07-15 |
| JPS6238350B2 (da) | 1987-08-17 |
| CH630369A5 (de) | 1982-06-15 |
| JPS52106877A (en) | 1977-09-07 |
| ES454160A1 (es) | 1978-03-01 |
| US4085211A (en) | 1978-04-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |