BE823411A - Nouveaux derives de la phenoxypropylamine et procede pour leur preparation - Google Patents
Nouveaux derives de la phenoxypropylamine et procede pour leur preparationInfo
- Publication number
- BE823411A BE823411A BE151557A BE151557A BE823411A BE 823411 A BE823411 A BE 823411A BE 151557 A BE151557 A BE 151557A BE 151557 A BE151557 A BE 151557A BE 823411 A BE823411 A BE 823411A
- Authority
- BE
- Belgium
- Prior art keywords
- phenoxypropylamine
- preparation
- new derivatives
- derivatives
- new
- Prior art date
Links
- DXVQSHRBALIFBC-UHFFFAOYSA-N 3-phenoxypropan-1-amine Chemical class NCCCOC1=CC=CC=C1 DXVQSHRBALIFBC-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/38—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT1066673A AT334385B (de) | 1973-12-20 | 1973-12-20 | Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE823411A true BE823411A (fr) | 1975-06-16 |
Family
ID=3623884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE151557A BE823411A (fr) | 1973-12-20 | 1974-12-16 | Nouveaux derives de la phenoxypropylamine et procede pour leur preparation |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4034009A (cs) |
| JP (2) | JPS5412461B2 (cs) |
| AT (1) | AT334385B (cs) |
| BE (1) | BE823411A (cs) |
| CA (1) | CA1001626A (cs) |
| CH (1) | CH612417A5 (cs) |
| CS (1) | CS185669B2 (cs) |
| DD (1) | DD118421A1 (cs) |
| ES (1) | ES433145A1 (cs) |
| FR (1) | FR2255058B1 (cs) |
| GB (1) | GB1441359A (cs) |
| IE (1) | IE40310B1 (cs) |
| IL (1) | IL46259A (cs) |
| LU (2) | LU71514A1 (cs) |
| PL (1) | PL94095B1 (cs) |
| RO (1) | RO69147A (cs) |
| SU (1) | SU547174A3 (cs) |
| YU (1) | YU36492B (cs) |
| ZA (1) | ZA748067B (cs) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4177280A (en) * | 1978-07-03 | 1979-12-04 | Syntex (U.S.A.) Inc. | Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents |
| JPS5757231U (cs) * | 1980-09-19 | 1982-04-03 | ||
| US4470965A (en) * | 1982-10-27 | 1984-09-11 | Usv Pharmaceutical Corporation | Celiprolol for the treatment of glaucoma |
| DE3410380A1 (de) * | 1984-03-21 | 1985-10-10 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu dessen herstellung, verwendung in der therapie und pharmazeutische zubereitungen |
| DE3544172A1 (de) * | 1985-12-13 | 1987-06-19 | Lentia Gmbh | Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung |
| DE3636209A1 (de) * | 1986-10-24 | 1988-04-28 | Lentia Gmbh | Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates |
| EP1545519B1 (en) | 2002-08-19 | 2011-03-23 | Pfizer Inc. | Combination therapy for hyperproliferative diseases |
| AU2004242777B2 (en) * | 2003-05-30 | 2011-05-12 | Ranbaxy Laboratories Limited | Substituted pyrrole derivatives and their use as HMG-Co inhibitors |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| WO2007029155A2 (en) * | 2005-09-05 | 2007-03-15 | Ranbaxy Laboratories Limited | An improved process for preparation of pure celiprolol base |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| CA2627599A1 (en) * | 2005-11-08 | 2007-05-18 | Ranbaxy Laboratories Limited | Process for (3r,5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxy methyl phenyl amino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid hemi calcium salt |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| TW200744583A (en) * | 2006-03-14 | 2007-12-16 | Ranbaxy Lab Ltd | Statin stabilizing dosage formulations |
| WO2008010087A2 (en) * | 2006-07-14 | 2008-01-24 | Ranbaxy Laboratories Limited | Polymorphic forms of an hmg-coa reductase inhibitor and uses thereof |
| EP2094643B1 (en) | 2006-12-01 | 2012-02-29 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
| CA2688161C (en) | 2007-06-04 | 2020-10-20 | Kunwar Shailubhai | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US20100120694A1 (en) | 2008-06-04 | 2010-05-13 | Synergy Pharmaceuticals, Inc. | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| EP2050441A1 (en) * | 2007-10-19 | 2009-04-22 | Université Victor Segalen Bordeaux 2 | Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
| US8987262B2 (en) | 2007-10-19 | 2015-03-24 | Universite de Bordeaux | Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
| AU2014274812B2 (en) | 2013-06-05 | 2018-09-27 | Bausch Health Ireland Limited | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| ES3007652T3 (en) | 2019-01-18 | 2025-03-20 | Astrazeneca Ab | 6'-[[(1s,3s)-3-[[5-(difluoromethoxy)-2-pyrimidinyl]amino]cyclopentyl]amino][1(2h),3'-bipyridin]-2-one as pcsk9 inhibitor and methods of use thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1214012A (en) * | 1967-12-21 | 1970-11-25 | Allen & Hanburys Ltd | Phenylethanolamines |
| AT292671B (de) * | 1967-12-22 | 1971-09-10 | May & Baker Ltd | Verfahren zur Herstellung von neuen 3-(4'-Alkanoylamino-2'-acylphenoxy)-2-hydroxy-1-aminopropanen |
| US3935259A (en) * | 1970-01-08 | 1976-01-27 | Ciba-Geigy Corporation | New amines and processes for their manufacture |
| SE354851B (cs) * | 1970-02-18 | 1973-03-26 | Haessle Ab | |
| NL7115581A (cs) * | 1970-11-13 | 1972-05-16 | Dresden Arzneimittel | |
| GB1396322A (en) * | 1971-06-15 | 1975-06-04 | Ici Ltd | Alkanolamine derivatives |
| GB1393675A (en) | 1971-06-16 | 1975-05-07 | Ici Ltd | Alkanolamine derivatives |
| SE386892B (sv) * | 1972-07-06 | 1976-08-23 | Haessle Ab | Forfarande for framstellning av oxaminoforeningar |
| GB1455116A (en) * | 1972-12-15 | 1976-11-10 | Ici Ltd | Pharmaceutical compositions |
| AT330150B (de) * | 1973-02-28 | 1976-06-10 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen |
| GB1460593A (en) * | 1973-06-22 | 1977-01-06 | Ici Ltd | Ethanolamine derivatives |
| FI65987C (fi) * | 1973-12-12 | 1984-08-10 | Ici Ltd | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat |
| AT334386B (de) * | 1973-12-21 | 1976-01-10 | Chemie Linz Ag | Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen |
-
1973
- 1973-12-20 AT AT1066673A patent/AT334385B/de active
-
1974
- 1974-12-05 CH CH1617574A patent/CH612417A5/xx not_active IP Right Cessation
- 1974-12-11 YU YU03277/74A patent/YU36492B/xx unknown
- 1974-12-16 BE BE151557A patent/BE823411A/xx active Protection Beyond IP Right Term
- 1974-12-16 IL IL46259A patent/IL46259A/xx unknown
- 1974-12-16 GB GB5432674A patent/GB1441359A/en not_active Expired
- 1974-12-16 IE IE2585/74A patent/IE40310B1/en not_active IP Right Cessation
- 1974-12-17 US US05/533,688 patent/US4034009A/en not_active Expired - Lifetime
- 1974-12-17 CA CA216,299A patent/CA1001626A/en not_active Expired
- 1974-12-18 LU LU71514A patent/LU71514A1/xx unknown
- 1974-12-18 DD DD183145A patent/DD118421A1/xx unknown
- 1974-12-18 ZA ZA00748067A patent/ZA748067B/xx unknown
- 1974-12-19 PL PL1974176602A patent/PL94095B1/pl unknown
- 1974-12-19 ES ES433145A patent/ES433145A1/es not_active Expired
- 1974-12-19 FR FR7442008A patent/FR2255058B1/fr not_active Expired
- 1974-12-20 SU SU2086133A patent/SU547174A3/ru active
- 1974-12-20 JP JP14586074A patent/JPS5412461B2/ja not_active Expired
- 1974-12-20 RO RO7480894A patent/RO69147A/ro unknown
- 1974-12-20 CS CS7400008838A patent/CS185669B2/cs unknown
-
1978
- 1978-04-06 JP JP3982678A patent/JPS53149947A/ja active Granted
-
1993
- 1993-06-09 LU LU88296C patent/LU88296I2/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS53149947A (en) | 1978-12-27 |
| JPS5412461B2 (cs) | 1979-05-23 |
| ES433145A1 (es) | 1976-11-16 |
| JPS5095246A (cs) | 1975-07-29 |
| AU7653874A (en) | 1976-06-17 |
| LU88296I2 (fr) | 1994-05-04 |
| LU71514A1 (cs) | 1975-08-20 |
| CH612417A5 (cs) | 1979-07-31 |
| IL46259A0 (en) | 1975-03-13 |
| GB1441359A (en) | 1976-06-30 |
| YU327774A (en) | 1982-02-25 |
| SU547174A3 (ru) | 1977-02-15 |
| CS185669B2 (en) | 1978-10-31 |
| AT334385B (de) | 1976-01-10 |
| PL94095B1 (cs) | 1977-07-30 |
| IE40310L (en) | 1975-06-20 |
| ATA1066673A (de) | 1976-05-15 |
| ZA748067B (en) | 1976-01-28 |
| FR2255058B1 (cs) | 1978-07-28 |
| US4034009A (en) | 1977-07-05 |
| IE40310B1 (en) | 1979-04-25 |
| IL46259A (en) | 1978-04-30 |
| FR2255058A1 (cs) | 1975-07-18 |
| YU36492B (en) | 1984-02-29 |
| CA1001626A (en) | 1976-12-14 |
| DD118421A1 (cs) | 1976-03-05 |
| JPS5549071B2 (cs) | 1980-12-10 |
| RO69147A (ro) | 1981-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CCPA | Application for a supplementary protection certificate |
Free format text: 093C0095 |
|
| CN | Change of patent owner's name | ||
| RE20 | Patent expired |
Owner name: RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. Effective date: 19941216 |
|
| CCPV | Grant of a supplementary protection certificate |
Free format text: 093C0095, EXPIRES 19991216 |