BE763745A - 1-(benzyl substitue)tetrahydro-2-(1h)pyrimidones - Google Patents

1-(benzyl substitue)tetrahydro-2-(1h)pyrimidones

Info

Publication number
BE763745A
BE763745A BE763745A BE763745A BE763745A BE 763745 A BE763745 A BE 763745A BE 763745 A BE763745 A BE 763745A BE 763745 A BE763745 A BE 763745A BE 763745 A BE763745 A BE 763745A
Authority
BE
Belgium
Prior art keywords
pyrimidons
tetrahydro
benzyl substitute
substitute
benzyl
Prior art date
Application number
BE763745A
Other languages
English (en)
French (fr)
Inventor
T J Schwan
S E Burrouset J L Butterfield
Original Assignee
Norwich Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwich Pharma Co filed Critical Norwich Pharma Co
Publication of BE763745A publication Critical patent/BE763745A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Joining Of Building Structures In Genera (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
BE763745A 1970-03-05 1971-03-03 1-(benzyl substitue)tetrahydro-2-(1h)pyrimidones BE763745A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1698270A 1970-03-05 1970-03-05

Publications (1)

Publication Number Publication Date
BE763745A true BE763745A (fr) 1971-09-03

Family

ID=21780073

Family Applications (1)

Application Number Title Priority Date Filing Date
BE763745A BE763745A (fr) 1970-03-05 1971-03-03 1-(benzyl substitue)tetrahydro-2-(1h)pyrimidones

Country Status (14)

Country Link
US (1) US3681349A (enExample)
AT (1) AT305288B (enExample)
BE (1) BE763745A (enExample)
CH (1) CH555343A (enExample)
DE (1) DE2110445C3 (enExample)
DK (1) DK127427B (enExample)
ES (1) ES388780A1 (enExample)
FR (1) FR2085673B1 (enExample)
GB (1) GB1294626A (enExample)
IL (1) IL36189A0 (enExample)
NL (1) NL7102519A (enExample)
NO (1) NO130728C (enExample)
SE (1) SE376420B (enExample)
ZA (1) ZA71928B (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL39003A (en) * 1971-03-25 1975-02-10 Morton Norwich Products Inc 1-(substituted benzyl)tetrahydro-2-(1h)-pyrimidones and their preparation
US3957785A (en) * 1971-12-02 1976-05-18 Societa' Farmaceutici Italia S.P.A. Bβ-Pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives
US3956325A (en) * 1974-01-21 1976-05-11 Smithkline Corporation 5-Heterocyclic-1,2,3,6-tetrahydro-4(5H) pyrimidinone
US4003900A (en) * 1976-03-11 1977-01-18 Morton-Norwich Products, Inc. 1-Benzyl-5-chloro-2-(1H)-pyrimidone
US4002627A (en) * 1976-03-26 1977-01-11 Morton-Norwich Products, Inc. 1-Benzyl-3-methyl-3,4,5,6-tetrahydro-2(1H) pyrimidone
US4052399A (en) * 1976-09-13 1977-10-04 Morton-Norwich Products, Inc. 1-[2-(Hexahydro-1H-azepino)ethyl]-2(1H)pyrimidone dihydrochloride
US4052400A (en) * 1976-10-29 1977-10-04 Morton-Norwich Products, Inc. Hypertensive 1-substituted 2(1h)-pyrimidones
US8835426B2 (en) * 2007-02-26 2014-09-16 Vitae Pharmaceuticals, Inc. Cyclic urea and carbamate inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5451611B2 (ja) * 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
CA2708303A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2714532A1 (en) * 2008-02-11 2009-08-20 Vitae Pharmaceuticals, Inc. 1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
US8598160B2 (en) * 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CA2718264A1 (en) * 2008-03-18 2009-09-24 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
KR20110002492A (ko) * 2008-05-01 2011-01-07 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
TW201004945A (en) * 2008-05-01 2010-02-01 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2291370B1 (en) * 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723032A1 (en) * 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2729993A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
WO2010011314A1 (en) * 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
US8846668B2 (en) 2008-07-25 2014-09-30 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5679997B2 (ja) 2009-02-04 2015-03-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
TW201039034A (en) * 2009-04-27 2010-11-01 Chunghwa Picture Tubes Ltd Pixel structure and the method of forming the same
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
KR20120061771A (ko) * 2009-04-30 2012-06-13 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
WO2011002910A1 (en) 2009-07-01 2011-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2496589B1 (en) 2009-11-05 2014-03-05 Boehringer Ingelheim International GmbH Novel chiral phosphorus ligands
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
EP2576570A1 (en) 2010-05-26 2013-04-10 Boehringer Ingelheim International GmbH 2-oxo-1,2-dihydropyridin-4-ylboronic acid derivatives
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
WO2011161128A1 (en) 2010-06-25 2011-12-29 Boehringer Ingelheim International Gmbh Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders
CA2813671A1 (en) 2010-11-02 2012-05-10 Boehringer Ingelheim International Gmbh Pharmaceutical combinations for the treatment of metabolic disorders
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE562987A (enExample) * 1956-12-05
DE1121617B (de) * 1959-05-26 1962-01-11 Huels Chemische Werke Ag Verfahren zur Herstellung von Tetrahydropyrimidin-2-onderivaten
DE1545601A1 (de) * 1965-07-22 1969-08-07 Basf Ag Verfahren zur Herstellung von Hexahydro-pyrimidinderivaten
DE1670368A1 (de) * 1966-07-16 1970-11-05 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung aralkylsubstituierter Lactame und Cyclischer Harnstoffe
DE1670241A1 (de) * 1967-07-01 1971-01-28 Basf Ag Verfahren zur Herstellung von 2-Oxohexahydropyrimidinen

Also Published As

Publication number Publication date
CH555343A (de) 1974-10-31
SE376420B (enExample) 1975-05-26
FR2085673A1 (enExample) 1971-12-31
US3681349A (en) 1972-08-01
DK127427B (da) 1973-11-05
ES388780A1 (es) 1975-03-01
ZA71928B (en) 1972-09-27
GB1294626A (en) 1972-11-01
NO130728C (enExample) 1975-01-29
DE2110445B2 (de) 1974-10-10
NL7102519A (enExample) 1971-09-07
IL36189A0 (en) 1971-04-28
AT305288B (de) 1973-02-26
DE2110445C3 (de) 1975-05-28
DE2110445A1 (de) 1971-11-04
FR2085673B1 (enExample) 1974-09-06
NO130728B (enExample) 1974-10-21

Similar Documents

Publication Publication Date Title
DK127427B (da) Analogifremgangsmåde til fremstilling af 1-(substitueret benzyl)-tetrahydro-2-(1H)-pyrimidoner.
AT329170B (de) Stockpunkterniedriger
AT309888B (de) Herbizid
SE7607857L (sv) Lagerkonstruktion
BG18573A3 (bg) Хербицидно средство
BE804421A (fr) Cisaille
AT311713B (de) Herbizid
IT993382B (it) Elemento per costruzioni
DK136512C (da) Herbicid
ES170885Y (es) Elemento de construccion.
BE768908A (fr) Colles
IT1008004B (it) Biocidi
BE781158A (fr) 1-(benzyl substitue)-2-(1h)pyrimidones et 1-(benzyl substitue)-tetrahydro-2-(1h)-pyrimidones
CH552893A (de) Akkumulator.
AT310496B (de) Herbizid
AT306430B (de) Herbizid
CA900482A (en) 1-(substituted benzyl)tetrahydro-2-(1h) pyrimidones
AT329300B (de) Piezoelektrische baueinheit
AT310491B (de) Herbizid
AT306429B (de) Herbizid
AT306432B (de) Herbizid
BG17709A3 (bg) Хербицидно средство
BG17452A3 (bg) Хербицидно средство
BG18580A3 (bg) Хербицидно средство
BE772238A (fr) Herbicide