BE750139A - - Google Patents

Info

Publication number
BE750139A
BE750139A BE750139DA BE750139A BE 750139 A BE750139 A BE 750139A BE 750139D A BE750139D A BE 750139DA BE 750139 A BE750139 A BE 750139A
Authority
BE
Belgium
Application number
Inventor
F Bossert
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BE750139A publication Critical patent/BE750139A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE750139D 1969-05-10 1970-05-08 BE750139A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1923990A DE1923990C3 (de) 1969-05-10 1969-05-10 Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern

Publications (1)

Publication Number Publication Date
BE750139A true BE750139A (fr) 1970-11-09

Family

ID=5733869

Family Applications (1)

Application Number Title Priority Date Filing Date
BE750139D BE750139A (fr) 1969-05-10 1970-05-08

Country Status (15)

Country Link
US (1) US3773773A (fr)
JP (1) JPS4935277B1 (fr)
AT (1) AT299200B (fr)
BE (1) BE750139A (fr)
BR (1) BR6915159D0 (fr)
DE (1) DE1923990C3 (fr)
DK (1) DK136246B (fr)
FI (1) FI52078C (fr)
FR (1) FR2051515B1 (fr)
GB (1) GB1305793A (fr)
IL (1) IL34304A (fr)
NL (1) NL7006628A (fr)
NO (1) NO133274C (fr)
SE (1) SE376915B (fr)
YU (1) YU33268B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466972A (en) * 1977-06-20 1984-08-21 Sandoz Ltd. Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
US4500532A (en) * 1983-03-03 1985-02-19 Usv Pharmaceutical Corporation 1-(Substituted aminoalkyl)-1,4-dihydropyridines

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963188A1 (de) * 1969-12-17 1971-06-24 Bayer Ag Neue Cyanphenyl-1,4-dihydropyridinderivate
DE2117572C3 (de) * 1971-04-10 1980-03-20 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
GB1430961A (en) * 1972-01-22 1976-04-07 Yamanouchi Pharma Co Ltd 1-substituted-1,4-dihyddrypyridine derivatives
US4021434A (en) * 1972-01-22 1977-05-03 Yamanouchi Pharmaceutical Co., Ltd. Sodium β-[2,6-dimethyl-3,5-bis(ethoxycarbonyl)-4-(3-nitrophenyl)-1,4-dihydropyridine-1-yl]ethyl sulfate
DE2210674C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
US3935223A (en) * 1972-03-06 1976-01-27 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
US3939171A (en) * 1972-03-06 1976-02-17 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
US3917620A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-4,5-dihydropyridine derivatives
US3857849A (en) * 1973-02-28 1974-12-31 Bayer Ag 2-amino-1,4-dihydropyridine derivatives
US3957998A (en) * 1972-03-06 1976-05-18 Bayer Aktiengesellschaft Use of 2,6-diamino-4-substituted-1,4-dihydropyridine-3,5-dicarboxylic acid esters for effecting coronary vessel dilation and treating hypertension
US3887558A (en) * 1972-03-06 1975-06-03 Bayer Ag Process for producing 2,6-diamino -1,4- dihydro-3,5-pyridine-dicarboxylates and derivatives thereof
DD106832A5 (fr) * 1972-03-06 1974-07-05
US3933834A (en) * 1972-03-06 1976-01-20 Bayer Aktiengesellschaft Unsymmetrical esters of N-substituted 1,4-dihydropyridine 3,5-dicarboxylic acid
US3988458A (en) * 1972-03-06 1976-10-26 Bayer Aktiengesellschaft Bicyclic derivatives of 1,4-dihydropyridine 3,5-carboxylic acid esters
US3992545A (en) * 1972-03-06 1976-11-16 Bayer Aktiengesellschaft 2-Amino-4,5-dihydropyridine derivatives in pharmaceutical compositions
US3985886A (en) * 1972-03-06 1976-10-12 Bayer Aktiengesellschaft 2-Amino-4,5-dihydropyridine derivatives and process for their preparation
DE2218644C3 (de) * 1972-04-18 1982-08-19 Bayer Ag, 5090 Leverkusen Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2228363A1 (de) * 1972-06-10 1974-01-03 Bayer Ag 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US3968117A (en) * 1972-06-10 1976-07-06 Bayer Aktiengesellschaft 1,4-Dihydropyridines
DE2239815C2 (de) * 1972-08-12 1983-02-10 Bayer Ag, 5090 Leverkusen 2-Alkylamino-dihydropyridine, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
US4136187A (en) * 1972-08-12 1979-01-23 Bayer Aktiengesellschaft Antihypertensive 2-amino-4,5-dihydropyridine derivatives
DE2242787C2 (de) * 1972-08-31 1982-01-21 Bayer Ag, 5090 Leverkusen 4-Phenyl-6-amino-3,4-dihydropyridon-(2)-3,5-dicarbonsäure-diäthylesterderivate, ein Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2242786A1 (de) * 1972-08-31 1974-03-14 Bayer Ag Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
FR2218107A1 (en) * 1973-02-20 1974-09-13 Yamanouchi Pharma Co Ltd Amino alkyl 2,6-dialkyl-4-aryl-1,4 dihydropyridine-3, carboxylates - useful as cerebral vasodilators and musculotropic spasmolytic agents
US4002762A (en) * 1973-03-03 1977-01-11 Bayer Aktiengesellschaft 2-Amino-3,4-dihydropyridines used to effect coronary vessel dilation and treat hypertension
GB1425729A (en) * 1973-06-12 1976-02-18 Smith Kline French Lab 1,4-dihydropyridine compounds
US4020178A (en) * 1973-07-12 1977-04-26 Bayer Aktiengesellschaft 1,4-Dihydropyridine esters used as coronary dilators and anti-hypertensives
DE2335466A1 (de) * 1973-07-12 1975-01-30 Bayer Ag Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
DE2738153A1 (de) * 1977-08-24 1979-03-08 Bayer Ag 2-pyridyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FR2405937A1 (fr) * 1977-10-14 1979-05-11 Labaz Nouveaux derives de dihydropyridine, leur procede de preparation et leur application
SU798099A1 (ru) * 1978-03-06 1981-01-23 Ордена Трудового Красного Знамениинститут Органического Синтезаан Латвийской Ccp 1-Бензил-2,6-диметил-4-о-или-M-НиТРОфЕНил-3,5-диэТОКСиКАРбОНил- 1,4-дигидРОпиРидиНы, пРО Вл ющиЕКОРОНАРОдилАТиРующую АКТиВНОСТь
DE3022030A1 (de) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
US4365063A (en) * 1981-08-31 1982-12-21 American Home Products Corporation Antihypertensive agents
US4321384A (en) * 1981-02-27 1982-03-23 American Home Products Corporation Antihypertensive agents
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
JPS58159490A (ja) * 1982-02-23 1983-09-21 Nikken Kagaku Kk １，４−ジヒドロピリジン化合物
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
EP0388482B1 (fr) * 1989-03-20 1994-07-06 Siemens Aktiengesellschaft Mélange photosensible
US5258521A (en) * 1989-07-26 1993-11-02 Tosoh Corporation Process of producing optically active propionic acid ester derivatives
DE4011695A1 (de) * 1990-04-11 1991-10-17 Bayer Ag Verwendung von n-alkylierten 1,4-dihydropyridindicarbonsaeureestern als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung
DE4125271A1 (de) * 1991-07-31 1993-02-11 Bayer Ag Neue n-alkylierte 1,4-dihydropyridindicarbonsaeureester
DE4133257A1 (de) * 1991-10-08 1993-04-15 Bayer Ag N-methyl-nimodipin, verfahren zu seiner herstellung und seine verwendung als zerebraltherapeutikum
DE4223867A1 (de) * 1992-07-20 1994-01-27 Bayer Ag Spezieller 1,4-Dihydropyridin-3,5-dicarbonsäureester, Verfahren zu seiner Herstellung und seine pharmazeutische Verwendung
DE4430094A1 (de) 1994-08-25 1996-02-29 Bayer Ag Verwendung von 3,5-Dicarbonsäureester-1,4-Dihydropyridinen als Arzneimittel
JPH1039510A (ja) * 1996-07-29 1998-02-13 Nitto Denko Corp ネガ型フォトレジスト組成物及びその利用
DE69837282T2 (de) * 1997-12-13 2007-11-08 Bristol-Myers Squibb Co. VERWENDUNG VON PYRAZOLO Ä 3,4-bÜ PYRIDIN ALS CYCLIN-ABHÄNGIGE KINASE HEMMER
US6653481B2 (en) * 2000-12-29 2003-11-25 Synthon Bv Process for making amlodipine
CA2854252C (fr) * 2011-11-24 2016-11-29 Lipidart Kutato Fejleszto Es Tanacsado Kft. Derives de 1,4-dihydropyridine ayant une activite modulant hsp

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3325505A (en) * 1965-02-24 1967-06-13 Smith Kline French Lab 4-cycloalkyl(or cycloalkenyl)-dihydropyridines
US3441648A (en) * 1967-02-07 1969-04-29 Smithkline Corp Compositions and methods for lowering blood pressure with 1,4-dihydropyridines

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466972A (en) * 1977-06-20 1984-08-21 Sandoz Ltd. Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
US4500532A (en) * 1983-03-03 1985-02-19 Usv Pharmaceutical Corporation 1-(Substituted aminoalkyl)-1,4-dihydropyridines

Also Published As

Publication number Publication date
IL34304A0 (en) 1970-06-17
FI52078B (fr) 1977-02-28
FI52078C (fi) 1977-06-10
FR2051515A1 (fr) 1971-04-09
NL7006628A (fr) 1970-11-12
JPS4935277B1 (fr) 1974-09-20
BR6915159D0 (pt) 1973-04-19
SE376915B (fr) 1975-06-16
YU33268B (en) 1976-08-31
NO133274C (fr) 1976-04-07
NO133274B (fr) 1975-12-29
US3773773A (en) 1973-11-20
FR2051515B1 (fr) 1974-07-12
DE1923990C3 (de) 1978-11-23
DK136246C (fr) 1978-02-13
DE1923990A1 (de) 1970-11-19
GB1305793A (fr) 1973-02-07
YU102670A (en) 1976-03-31
IL34304A (en) 1973-06-29
DK136246B (da) 1977-09-12
AT299200B (de) 1972-06-12
DE1923990B2 (de) 1978-03-30

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