BE745560A - Nouvelles tetrahydrobenzothienodiazepinones et procedes pour les preparer - Google Patents

Nouvelles tetrahydrobenzothienodiazepinones et procedes pour les preparer

Info

Publication number
BE745560A
BE745560A BE745560DA BE745560A BE 745560 A BE745560 A BE 745560A BE 745560D A BE745560D A BE 745560DA BE 745560 A BE745560 A BE 745560A
Authority
BE
Belgium
Prior art keywords
tetrahydrobenzothienodiazepinones
preparing
new
methods
new tetrahydrobenzothienodiazepinones
Prior art date
Application number
Other languages
English (en)
Inventor
F J Tinney
Original Assignee
Parke Davis & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis & Co filed Critical Parke Davis & Co
Publication of BE745560A publication Critical patent/BE745560A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/36—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74—Naphthothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/005—Stabilisers against oxidation, heat, light, ozone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
BE745560D 1967-04-21 1970-02-05 Nouvelles tetrahydrobenzothienodiazepinones et procedes pour les preparer BE745560A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH573567 1967-04-21
US79727469A 1969-02-06 1969-02-06
US85479069A 1969-09-02 1969-09-02
US15611871A 1971-06-23 1971-06-23

Publications (1)

Publication Number Publication Date
BE745560A true BE745560A (fr) 1970-07-16

Family

ID=27428927

Family Applications (2)

Application Number Title Priority Date Filing Date
BE713976D BE713976A (fr) 1967-04-21 1968-04-19
BE745560D BE745560A (fr) 1967-04-21 1970-02-05 Nouvelles tetrahydrobenzothienodiazepinones et procedes pour les preparer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BE713976D BE713976A (fr) 1967-04-21 1968-04-19

Country Status (7)

Country Link
US (3) US3697513A (fr)
BE (2) BE713976A (fr)
CH (2) CH540247A (fr)
DE (2) DE1768204A1 (fr)
FR (2) FR1562477A (fr)
GB (2) GB1224664A (fr)
NL (2) NL6805579A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081520A1 (fr) * 1970-02-17 1971-12-03 Yoshitomi Pharmaceutical

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4158099A (en) * 1967-07-14 1979-06-12 Ciba-Geigy Ag Production of aromatic compounds containing ethylene double bonds
GB1256548A (fr) * 1968-12-10 1971-12-08
US3880838A (en) * 1970-12-16 1975-04-29 Squibb & Sons Inc Amino acid derivatives
US3872114A (en) * 1971-02-05 1975-03-18 Hoechst Ag Benzofurane derivatives, process for their manufacture and their use as optical brighteners
US3932301A (en) * 1971-02-23 1976-01-13 Sterling Drug Inc. Stilbene optical brighteners and compositions brightened therewith
US3681343A (en) * 1971-05-11 1972-08-01 Upjohn Co 6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines
US3872089A (en) * 1971-05-14 1975-03-18 Hoffmann La Roche Substituted thienodiazepines
GB1345998A (en) * 1971-05-31 1974-02-06 Yoshitomi Pharmaceutical Thienodiazepine compounds and pharmaceutical compositions containining them
BE787575A (fr) * 1971-08-13 1973-02-14 Hoechst Ag Derives de benzofuranne utilisables comme azureurs optiques
BE787576A (fr) * 1971-08-13 1973-02-14 Hoechst Ag Derives de benzofuranne et leur utilisation comme azureurs optiques
BE787580A (fr) * 1971-08-13 1973-02-14 Hoechst Ag Procede de preparation de derives du furanne
US4002423A (en) * 1971-08-13 1977-01-11 Hoechst Aktiengesellschaft Benzofuran derivatives process for their preparation and their use as optical brighteners
US3833510A (en) * 1972-02-07 1974-09-03 Sterling Drug Inc Optically brightened compositions with unsymmetrical carboxystyrylphenyl-containing compounds
US3974144A (en) * 1972-02-07 1976-08-10 Sterling Drug Inc. Compounds including carboxystyrylphenyl group
US4016156A (en) * 1972-06-30 1977-04-05 Ciba-Geigy Corporation Distyryl compounds
CH574950A5 (fr) * 1972-06-30 1976-04-30 Ciba Geigy Ag
US3993645A (en) * 1973-05-29 1976-11-23 Sterling Drug Inc. Stilbene optical brighteners and compositions brightened therewith
US4008224A (en) * 1973-11-19 1977-02-15 Ciba-Geigy Corporation Process for the manufacture of cyano-substituted stilbene compounds
DE2525683A1 (de) * 1974-06-12 1976-01-02 Ciba Geigy Ag Sulfogruppenhaltige heterocyclen
CH598309A5 (fr) * 1974-08-14 1978-04-28 Ciba Geigy Ag
CH598307A5 (fr) * 1974-08-14 1978-04-28 Ciba Geigy Ag
GB1544963A (en) * 1976-03-12 1979-04-25 Hexachimie Cyclopenta(b)thiophene derivatives
DE2730644A1 (de) * 1977-07-07 1979-01-25 Bayer Ag Fluoreszenz-farbstoffe
US4366189A (en) * 1979-12-21 1982-12-28 Ciba-Geigy Corporation 4-Heterocyclyl-4'-vinylstilbenes
US4346016A (en) * 1980-04-23 1982-08-24 Ciba-Geigy Corporation 6-Styrylquinoxalines, and their use as fluorescent brighteners
US4816473A (en) * 1983-07-14 1989-03-28 Syntex (U.S.A.) Inc. Aroyl benzofuran and benzothiophene acetic and propionic acids
CA1281325C (fr) * 1984-06-20 1991-03-12 Patrice C. Belanger Derives de benzofurane
US5087638A (en) * 1984-06-20 1992-02-11 Merck Frosst Canada, Inc. Benzofuran derivatives
US5112852A (en) * 1986-12-23 1992-05-12 Merrell Dow Pharmaceuticals Inc. Allenyl amines
DE4024206A1 (de) * 1990-07-31 1992-02-06 Basf Ag 2,2'-thienyl-benzothiophene, ihre herstellung und ihre verwendung zur bekaempfung von schaedlingen
US5234516A (en) * 1992-01-28 1993-08-10 Toyo Kohan Co., Ltd. Method for production of a polyethylene laminated metal sheet
US5939432A (en) * 1997-10-29 1999-08-17 Medco Research, Inc. Thiophenes useful for modulating the adenosine receptor
US6323214B1 (en) 1997-10-29 2001-11-27 Medco Research, Inc Allosteric adenosine receptor modulators
US6727258B2 (en) 1997-10-29 2004-04-27 King Pharmaceutical Research & Development, Inc. Allosteric adenosine receptor modulators
MY150088A (en) * 2003-05-19 2013-11-29 Irm Llc Immunosuppressant compounds and compositions
BRPI0410454A (pt) * 2003-05-19 2006-06-13 Irm Llc composições e compostos imunossupressores
AU2004251146A1 (en) * 2003-05-19 2005-01-06 Irm, Llc Immunosuppressant compounds and compositions
ITRM20030355A1 (it) * 2003-07-18 2005-01-19 Sigma Tau Ind Farmaceuti Composti ad attivita' citotossica derivati della combretastatina.
RU2552252C1 (ru) * 2014-02-25 2015-06-10 Юлия Алексеевна Щепочкина Бильярдный шар
TWI708770B (zh) * 2015-06-08 2020-11-01 日商捷恩智股份有限公司 具有苯并噻吩的液晶性化合物、液晶組成物及液晶顯示元件
TWI694068B (zh) * 2015-10-13 2020-05-21 日商捷恩智股份有限公司 具有苯並噻吩的液晶性化合物、液晶組成物和液晶顯示元件

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081520A1 (fr) * 1970-02-17 1971-12-03 Yoshitomi Pharmaceutical

Also Published As

Publication number Publication date
BE713976A (fr) 1968-10-21
DE2005276B2 (de) 1977-12-29
NL7001657A (fr) 1970-08-10
FR1562477A (fr) 1969-04-04
DE2005276C3 (de) 1978-08-31
US3558606A (en) 1971-01-26
CH513201A (fr) 1971-09-30
DE1768204A1 (de) 1971-06-03
GB1264606A (fr) 1972-02-23
CH540247A (de) 1973-09-28
FR2034523A1 (fr) 1970-12-11
NL144616B (nl) 1975-01-15
NL6805579A (fr) 1968-10-22
US3697513A (en) 1972-10-10
GB1224664A (en) 1971-03-10
US3706767A (en) 1972-12-19
DE2005276A1 (de) 1970-09-03

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: PARKE DAVIS & CY

Effective date: 19840205