FR2024846A1 - Pyrasinoyl-thio-semicarbazides et procedes pour leur preparation - Google Patents

Pyrasinoyl-thio-semicarbazides et procedes pour leur preparation

Info

Publication number
FR2024846A1
FR2024846A1 FR6938783A FR6938783A FR2024846A1 FR 2024846 A1 FR2024846 A1 FR 2024846A1 FR 6938783 A FR6938783 A FR 6938783A FR 6938783 A FR6938783 A FR 6938783A FR 2024846 A1 FR2024846 A1 FR 2024846A1
Authority
FR
France
Prior art keywords
pyrasinoyl
semicarbazides
thio
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6938783A
Other languages
English (en)
Inventor
Jethro Cragoe Edward Jr.
Leroy Shepard Kenneth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2024846A1 publication Critical patent/FR2024846A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
FR6938783A 1968-11-13 1969-11-12 Pyrasinoyl-thio-semicarbazides et procedes pour leur preparation Withdrawn FR2024846A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77554268A 1968-11-13 1968-11-13

Publications (1)

Publication Number Publication Date
FR2024846A1 true FR2024846A1 (fr) 1970-09-04

Family

ID=25104737

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6938783A Withdrawn FR2024846A1 (fr) 1968-11-13 1969-11-12 Pyrasinoyl-thio-semicarbazides et procedes pour leur preparation

Country Status (4)

Country Link
US (1) US3555023A (fr)
DE (1) DE1956859A1 (fr)
FR (1) FR2024846A1 (fr)
NL (1) NL6915952A (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20050090505A1 (en) * 2003-08-18 2005-04-28 Johnson Michael R. Methods of reducing risk of infection from pathogens
US7745442B2 (en) * 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
US20090253714A1 (en) * 2003-08-20 2009-10-08 Johnson Michael R Methods of reducing risk of infection from pathogens
US20070021439A1 (en) * 2005-07-25 2007-01-25 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
US9029382B2 (en) 2012-12-17 2015-05-12 Parion Sciences, Inc. 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds
EP3150585A1 (fr) 2012-12-17 2017-04-05 Parion Sciences, Inc. Dérivés de carboxamide de chloro-pyrazine avec une activité de blocage de canal de sodium épithélial
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Also Published As

Publication number Publication date
DE1956859A1 (de) 1970-06-04
NL6915952A (fr) 1970-05-15
US3555023A (en) 1971-01-12

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Legal Events

Date Code Title Description
RE Withdrawal of published application