BE689071A - - Google Patents

Info

Publication number
BE689071A
BE689071A BE689071DA BE689071A BE 689071 A BE689071 A BE 689071A BE 689071D A BE689071D A BE 689071DA BE 689071 A BE689071 A BE 689071A
Authority
BE
Belgium
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE689071A publication Critical patent/BE689071A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Jib Cranes (AREA)
BE689071D 1965-10-28 1966-10-28 BE689071A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB45657/65A GB1142654A (en) 1965-10-28 1965-10-28 Cyano-acetals and their use in benzylpyrimidine synthesis

Publications (1)

Publication Number Publication Date
BE689071A true BE689071A (fr) 1967-04-28

Family

ID=10438067

Family Applications (1)

Application Number Title Priority Date Filing Date
BE689071D BE689071A (fr) 1965-10-28 1966-10-28

Country Status (16)

Country Link
US (2) US3513185A (fr)
JP (1) JPS50657B1 (fr)
AT (1) AT271479B (fr)
BE (1) BE689071A (fr)
BR (1) BR6684142D0 (fr)
CH (1) CH484875A (fr)
DE (2) DE1793767C3 (fr)
DK (3) DK120546B (fr)
ES (1) ES332806A1 (fr)
FI (1) FI49716C (fr)
GB (1) GB1142654A (fr)
IL (1) IL26755A (fr)
NL (1) NL150442B (fr)
NO (1) NO127616B (fr)
PL (1) PL69908B1 (fr)
SE (3) SE390634B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1261455A (en) * 1969-03-06 1972-01-26 Burroughs Wellcome Co Improvements in or relating to substituted acrylonitriles
DE2065367C2 (de) * 1969-03-06 1985-04-04 The Wellcome Foundation Ltd., London Verfahren zur Herstellung von 2,4- Diamino-5-benzylpyrimidinen
BE789904A (fr) * 1971-10-12 1973-04-10 Wellcome Found Procedes de synthese organique
US3910984A (en) * 1972-11-27 1975-10-07 Plantex Ltd Benzylcyano-amides
USRE29467E (en) * 1971-12-20 1977-11-08 Plantex, Ltd. Benzylcyano-amides
AR207561A1 (es) * 1973-03-17 1976-10-15 Heumann Ludwig & Co Gmbh Procedimiento para la sintesis de 2,4-diamino 5(3'-metoxi-5'-substituido o no-4'alquildioxial-quilen-bencil)pirimidina
DK397574A (fr) * 1973-08-24 1975-04-28 Ciba Geigy Ag
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
DE2623170C2 (de) * 1976-05-22 1982-03-11 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von α-Cyanzimtaldehyd-Derivaten und 3,4,5-Trimethoxy-α-Cyanzimtaldehyd
GB1582245A (en) * 1976-06-09 1981-01-07 Wellcome Found Benzyl cyanoacetal derivatives and their conversion to pyrimidine derivatives
US4659861A (en) * 1981-11-03 1987-04-21 The Dow Chemical Company Novel nitrile functional glycol ether acetals
DE3211679A1 (de) * 1982-03-30 1983-10-06 Dynamit Nobel Ag Verfahren zur herstellung von acetalen und enolaethern aus acyloxymethylenverbindungen
JPS59120U (ja) * 1982-06-22 1984-01-05 株式会社タカハベッド 歩行練習器を兼ねた身障者用椅子
FR2602507B1 (fr) * 1986-08-08 1989-06-09 Sanofi Pharma Procede de preparation de diamino-2,4 benzyl-5 pyrimidines
CA2095518A1 (fr) * 1990-11-14 1992-05-15 Jeffrey M. Blaney Inhibition specifique de la dihydrofolate-reductase et composes utilises
CN103570631B (zh) * 2013-11-21 2016-05-25 华中农业大学 氚标记二甲氧苄啶的制备方法
CN103601688A (zh) * 2013-11-25 2014-02-26 四川大学 一种甲氧苄啶杂质的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3049544A (en) * 1962-08-14 Method for the preparation of
US2755298A (en) * 1956-07-17 pwiiq
US2745866A (en) * 1953-01-22 1956-05-15 Searle & Co Alpha, beta-diaryl substitution products of alpha-alkenonitriles
US2951089A (en) * 1953-12-28 1960-08-30 Schering Corp Alkyl ethers of polyiodophenyl propionic acids
US3128300A (en) * 1960-12-09 1964-04-07 Monsanto Chemicals 3-phenoxyacrylonitriles prepared by cyanovinylation reaction
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes

Also Published As

Publication number Publication date
ES332806A1 (es) 1967-10-01
DE1593723C3 (de) 1978-04-27
CH484875A (de) 1970-01-31
FI49716C (fi) 1975-09-10
PL69908B1 (fr) 1973-10-31
SE390634B (sv) 1977-01-03
US3513185A (en) 1970-05-19
GB1142654A (en) 1969-02-12
DK127415B (da) 1973-11-05
FI49716B (fr) 1975-06-02
DE1593723B2 (de) 1977-06-16
DK125849B (da) 1973-05-14
SE344746B (fr) 1972-05-02
DE1793767B2 (de) 1979-10-31
AT271479B (de) 1969-06-10
SE349580B (fr) 1972-10-02
JPS50657B1 (fr) 1975-01-10
US3671564A (en) 1972-06-20
DK120546B (da) 1971-06-14
NL150442B (nl) 1976-08-16
NO127616B (fr) 1973-07-23
DE1793767A1 (de) 1973-11-08
DE1593723A1 (de) 1972-04-13
DE1793767C3 (de) 1980-07-10
IL26755A (en) 1970-10-30
BR6684142D0 (pt) 1973-12-26
NL6615287A (fr) 1967-05-02

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: THE WELLCOME FOUNDATION LTD

Effective date: 19861028