BE636489A - - Google Patents
Info
- Publication number
- BE636489A BE636489A BE636489DA BE636489A BE 636489 A BE636489 A BE 636489A BE 636489D A BE636489D A BE 636489DA BE 636489 A BE636489 A BE 636489A
- Authority
- BE
- Belgium
- Prior art keywords
- sep
- nitro
- weight
- chloromethyl
- desc
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 12
- 239000000829 suppository Substances 0.000 claims description 8
- 208000010484 vulvovaginitis Diseases 0.000 claims description 7
- 230000001857 anti-mycotic effect Effects 0.000 claims description 6
- 239000002543 antimycotic Substances 0.000 claims description 6
- -1 chloro- Chemical class 0.000 claims description 6
- 230000002378 acidificating effect Effects 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 2
- 239000002535 acidifier Substances 0.000 claims 1
- YIUZDGLJEZOSGS-UHFFFAOYSA-N bis(3-methyl-5-nitrofuran-2-yl)methanone Chemical compound CC1=C(OC(=C1)[N+](=O)[O-])C(=O)C=1OC(=CC=1C)[N+](=O)[O-] YIUZDGLJEZOSGS-UHFFFAOYSA-N 0.000 claims 1
- 230000000855 fungicidal effect Effects 0.000 claims 1
- 239000000417 fungicide Substances 0.000 claims 1
- DQJAAEADFORVGZ-UHFFFAOYSA-N 2-chloro-1-(5-nitrofuran-2-yl)ethanone Chemical compound [O-][N+](=O)C1=CC=C(C(=O)CCl)O1 DQJAAEADFORVGZ-UHFFFAOYSA-N 0.000 description 8
- 239000000203 mixture Substances 0.000 description 7
- 239000002253 acid Substances 0.000 description 6
- 239000006216 vaginal suppository Substances 0.000 description 5
- 229940120293 vaginal suppository Drugs 0.000 description 5
- 230000000699 topical effect Effects 0.000 description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 3
- 206010046914 Vaginal infection Diseases 0.000 description 3
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 239000000155 melt Substances 0.000 description 3
- 241000233866 Fungi Species 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 125000006353 oxyethylene group Chemical group 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 229930194542 Keto Natural products 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 201000008100 Vaginitis Diseases 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- HMKCSFHWMJHMTG-UHFFFAOYSA-N bis(furan-2-yl)methanone Chemical compound C=1C=COC=1C(=O)C1=CC=CO1 HMKCSFHWMJHMTG-UHFFFAOYSA-N 0.000 description 1
- 210000003756 cervix mucus Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- IPCSVZSSVZVIGE-UHFFFAOYSA-M hexadecanoate Chemical compound CCCCCCCCCCCCCCCC([O-])=O IPCSVZSSVZVIGE-UHFFFAOYSA-M 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- IPCSVZSSVZVIGE-UHFFFAOYSA-N palmitic acid group Chemical group C(CCCCCCCCCCCCCCC)(=O)O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 229940126702 topical medication Drugs 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
Landscapes
- Health & Medical Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE636489A true BE636489A (h) |
Family
ID=202490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE636489D BE636489A (h) |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE636489A (h) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0024023A3 (en) * | 1979-08-11 | 1981-10-28 | Bayer Ag | Antimycotic agents with enhanced release of the active ingredients |
-
0
- BE BE636489D patent/BE636489A/fr unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0024023A3 (en) * | 1979-08-11 | 1981-10-28 | Bayer Ag | Antimycotic agents with enhanced release of the active ingredients |
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