BE539965A - - Google Patents
Info
- Publication number
- BE539965A BE539965A BE539965DA BE539965A BE 539965 A BE539965 A BE 539965A BE 539965D A BE539965D A BE 539965DA BE 539965 A BE539965 A BE 539965A
- Authority
- BE
- Belgium
- Prior art keywords
- acid
- reacted
- dimethyl
- gives
- hydrochloride
- Prior art date
Links
- 238000000034 method Methods 0.000 claims 11
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 6
- HXEACLLIILLPRG-YFKPBYRVSA-N L-pipecolic acid Chemical compound [O-]C(=O)[C@@H]1CCCC[NH2+]1 HXEACLLIILLPRG-YFKPBYRVSA-N 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 4
- HXEACLLIILLPRG-RXMQYKEDSA-N l-pipecolic acid Natural products OC(=O)[C@H]1CCCCN1 HXEACLLIILLPRG-RXMQYKEDSA-N 0.000 claims 4
- 239000002253 acid Substances 0.000 claims 3
- VAYGXNSJCAHWJZ-UHFFFAOYSA-N dimethyl sulfate Chemical compound COS(=O)(=O)OC VAYGXNSJCAHWJZ-UHFFFAOYSA-N 0.000 claims 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 3
- UFFBMTHBGFGIHF-UHFFFAOYSA-N 2,6-dimethylaniline Chemical compound CC1=CC=CC(C)=C1N UFFBMTHBGFGIHF-UHFFFAOYSA-N 0.000 claims 2
- MLPVBIWIRCKMJV-UHFFFAOYSA-N 2-ethylaniline Chemical compound CCC1=CC=CC=C1N MLPVBIWIRCKMJV-UHFFFAOYSA-N 0.000 claims 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 claims 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 125000001309 chloro group Chemical group Cl* 0.000 claims 2
- WNJUTBJQYFHURV-UHFFFAOYSA-N piperidine-3-carbonyl chloride Chemical compound ClC(=O)C1CCCNC1 WNJUTBJQYFHURV-UHFFFAOYSA-N 0.000 claims 2
- -1 piperidine-monocarboxylic acid halide Chemical class 0.000 claims 2
- VTVJMWZZVJSEMO-BYPYZUCNSA-N (2s)-pyrrolidine-2-carbonyl chloride Chemical compound ClC(=O)[C@@H]1CCCN1 VTVJMWZZVJSEMO-BYPYZUCNSA-N 0.000 claims 1
- XJLSEXAGTJCILF-RXMQYKEDSA-N (R)-nipecotic acid zwitterion Chemical compound OC(=O)[C@@H]1CCCNC1 XJLSEXAGTJCILF-RXMQYKEDSA-N 0.000 claims 1
- MPPPKRYCTPRNTB-UHFFFAOYSA-N 1-bromobutane Chemical compound CCCCBr MPPPKRYCTPRNTB-UHFFFAOYSA-N 0.000 claims 1
- NAMYKGVDVNBCFQ-UHFFFAOYSA-N 2-bromopropane Chemical compound CC(C)Br NAMYKGVDVNBCFQ-UHFFFAOYSA-N 0.000 claims 1
- WFNLHDJJZSJARK-UHFFFAOYSA-N 2-chloro-6-methylaniline Chemical compound CC1=CC=CC(Cl)=C1N WFNLHDJJZSJARK-UHFFFAOYSA-N 0.000 claims 1
- GCWYXRHXGLFVFE-UHFFFAOYSA-N 4-hydroxy-2,6-dimethylaniline Chemical compound CC1=CC(O)=CC(C)=C1N GCWYXRHXGLFVFE-UHFFFAOYSA-N 0.000 claims 1
- DSYFCRKFHZVMOS-UHFFFAOYSA-N CCCCOC(C=C1C)=CC(C)=C1NC(C1N(C)CCCC1)=O Chemical compound CCCCOC(C=C1C)=CC(C)=C1NC(C1N(C)CCCC1)=O DSYFCRKFHZVMOS-UHFFFAOYSA-N 0.000 claims 1
- VUHKTERBGMWQAY-UHFFFAOYSA-N N-(2-ethylphenyl)-1-propan-2-ylpiperidine-3-carboxamide Chemical compound C(C)C1=C(NC(C2CN(CCC2)C(C)C)=O)C=CC=C1 VUHKTERBGMWQAY-UHFFFAOYSA-N 0.000 claims 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 1
- 230000029936 alkylation Effects 0.000 claims 1
- 238000005804 alkylation reaction Methods 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 150000004982 aromatic amines Chemical class 0.000 claims 1
- AQNQQHJNRPDOQV-UHFFFAOYSA-N bromocyclohexane Chemical compound BrC1CCCCC1 AQNQQHJNRPDOQV-UHFFFAOYSA-N 0.000 claims 1
- BRTFVKHPEHKBQF-UHFFFAOYSA-N bromocyclopentane Chemical compound BrC1CCCC1 BRTFVKHPEHKBQF-UHFFFAOYSA-N 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- DENRZWYUOJLTMF-UHFFFAOYSA-N diethyl sulfate Chemical compound CCOS(=O)(=O)OCC DENRZWYUOJLTMF-UHFFFAOYSA-N 0.000 claims 1
- 229940008406 diethyl sulfate Drugs 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- INWLQCZOYSRPNW-UHFFFAOYSA-N mepivacaine Chemical compound CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C INWLQCZOYSRPNW-UHFFFAOYSA-N 0.000 claims 1
- AALBZAYEBOEAPQ-UHFFFAOYSA-N n-(2,6-dimethylphenyl)-1-ethylpiperidine-2-carboxamide Chemical compound CCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C AALBZAYEBOEAPQ-UHFFFAOYSA-N 0.000 claims 1
- GUTOQBOCGOYORW-UHFFFAOYSA-N n-methyl-n-phenylpiperidine-4-carboxamide Chemical compound C=1C=CC=CC=1N(C)C(=O)C1CCNCC1 GUTOQBOCGOYORW-UHFFFAOYSA-N 0.000 claims 1
- AKQIYQXGTBXWND-UHFFFAOYSA-N n-phenylpiperidine-4-carboxamide Chemical compound C1CNCCC1C(=O)NC1=CC=CC=C1 AKQIYQXGTBXWND-UHFFFAOYSA-N 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- PHXHRAOVMXOPIC-UHFFFAOYSA-N piperidine-4-carbonyl chloride Chemical compound ClC(=O)C1CCNCC1 PHXHRAOVMXOPIC-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE539965A true BE539965A (d) |
Family
ID=169485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE539965D BE539965A (d) |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE539965A (d) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1292142B (de) * | 1957-05-15 | 1969-04-10 | Bofors Ab | Verfahren zur Herstellung von ª‡-Picolinaniliden |
-
0
- BE BE539965D patent/BE539965A/fr unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1292142B (de) * | 1957-05-15 | 1969-04-10 | Bofors Ab | Verfahren zur Herstellung von ª‡-Picolinaniliden |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CH619935A5 (d) | ||
| CH616647A5 (d) | ||
| BE539965A (d) | ||
| CA1063619A (fr) | Procede de preparation de nouveaux acides benzylamino alcanoiques et les produits qui en resultent | |
| JP7357388B2 (ja) | 造影剤イオメプロールの製造方法 | |
| BE569836A (d) | ||
| FR2475541A1 (fr) | Nouveaux intermediaires de synthese de colorants | |
| BE539933A (d) | ||
| BE451559A (d) | ||
| CH342559A (fr) | Procédé de préparation de phénylcarbamates | |
| FR2468595A2 (fr) | Amides d'alkylene diamines, leur preparation et leur application en therapeutique | |
| BE482321A (d) | ||
| CH627163A5 (en) | Processes for the preparation of new indole derivatives | |
| BE554776A (d) | ||
| BE485826A (d) | ||
| BE503775A (d) | ||
| BE532238A (d) | ||
| BE519969A (d) | ||
| BE519972A (d) | ||
| BE721781A (d) | ||
| BE569837A (d) | ||
| BE570545A (d) | ||
| BE697625A (d) | ||
| BE504403A (d) | ||
| CH420107A (fr) | Procédé de préparation de nouveaux dérivés d'aralcoylaminoalcoylcyclohexanes substitués |