BE1009071A3 - Werkwijze voor de bereiding van een beta-lactam antibioticum. - Google Patents

Werkwijze voor de bereiding van een beta-lactam antibioticum. Download PDF

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Publication number
BE1009071A3
BE1009071A3 BE9500081A BE9500081A BE1009071A3 BE 1009071 A3 BE1009071 A3 BE 1009071A3 BE 9500081 A BE9500081 A BE 9500081A BE 9500081 A BE9500081 A BE 9500081A BE 1009071 A3 BE1009071 A3 BE 1009071A3
Authority
BE
Belgium
Prior art keywords
lactam
enzyme
acylating agent
beta
core
Prior art date
Application number
BE9500081A
Other languages
English (en)
Dutch (nl)
Inventor
Wilhelmus Hubertus Jos Boesten
Dooren Theodorus Johannes Van
Johanna Christina Maria Smeets
Original Assignee
Dsm Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE9500081A priority Critical patent/BE1009071A3/nl
Application filed by Dsm Nv filed Critical Dsm Nv
Priority to AU48462/96A priority patent/AU4846296A/en
Priority to PCT/NL1996/000051 priority patent/WO1996023796A1/fr
Priority to JP8523436A priority patent/JPH11503408A/ja
Priority to IN161MA1996 priority patent/IN182469B/en
Priority to PL96321626A priority patent/PL321626A1/xx
Priority to KR1019970705249A priority patent/KR100439322B1/ko
Priority to DE69614711T priority patent/DE69614711T2/de
Priority to AT96904336T priority patent/ATE204580T1/de
Priority to PCT/NL1996/000052 priority patent/WO1996023897A1/fr
Priority to EP96904337A priority patent/EP0815256A1/fr
Priority to IN162MA1996 priority patent/IN181940B/en
Priority to CZ972419A priority patent/CZ241997A3/cs
Priority to AU48461/96A priority patent/AU4846196A/en
Priority to ES96904336T priority patent/ES2163002T3/es
Priority to EP96904336A priority patent/EP0869961B1/fr
Priority to CN96192915A priority patent/CN1101395C/zh
Application granted granted Critical
Publication of BE1009071A3 publication Critical patent/BE1009071A3/nl
Priority to US08/903,879 priority patent/US5874571A/en
Priority to MX9705917A priority patent/MX9705917A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BE9500081A 1995-02-02 1995-02-02 Werkwijze voor de bereiding van een beta-lactam antibioticum. BE1009071A3 (nl)

Priority Applications (19)

Application Number Priority Date Filing Date Title
BE9500081A BE1009071A3 (nl) 1995-02-02 1995-02-02 Werkwijze voor de bereiding van een beta-lactam antibioticum.
EP96904337A EP0815256A1 (fr) 1995-02-02 1996-02-01 Procede de preparation d'une beta-lactamine
JP8523436A JPH11503408A (ja) 1995-02-02 1996-02-01 セファレキシンの回収方法
IN161MA1996 IN182469B (fr) 1995-02-02 1996-02-01
PL96321626A PL321626A1 (en) 1995-02-02 1996-02-01 Method of recovering ceophalexin
KR1019970705249A KR100439322B1 (ko) 1995-02-02 1996-02-01 세팔렉신의회수방법
DE69614711T DE69614711T2 (de) 1995-02-02 1996-02-01 Verfahren zur gewinnung von cephalexin
AT96904336T ATE204580T1 (de) 1995-02-02 1996-02-01 Verfahren zur gewinnung von cephalexin
AU48462/96A AU4846296A (en) 1995-02-02 1996-02-01 Process for the preparation of a beta -lactam antibiotic
PCT/NL1996/000051 WO1996023796A1 (fr) 1995-02-02 1996-02-01 Procede de recuperation de cefalexine
IN162MA1996 IN181940B (fr) 1995-02-02 1996-02-01
CZ972419A CZ241997A3 (cs) 1995-02-02 1996-02-01 Způsob oddělování cefalexinu
AU48461/96A AU4846196A (en) 1995-02-02 1996-02-01 Process for the recovery of cephalexin
ES96904336T ES2163002T3 (es) 1995-02-02 1996-02-01 Procedimiento para la recuperacion de cefalexina.
EP96904336A EP0869961B1 (fr) 1995-02-02 1996-02-01 Procede de recuperation de cefalexine
CN96192915A CN1101395C (zh) 1995-02-02 1996-02-01 头胞氨苄的回收方法
PCT/NL1996/000052 WO1996023897A1 (fr) 1995-02-02 1996-02-01 Procede de preparation d'une beta-lactamine
US08/903,879 US5874571A (en) 1995-02-02 1997-07-31 Process for the recovery of cephalexin
MX9705917A MX9705917A (es) 1995-02-02 1997-08-01 Procedimiento para la recuperacion de cefalexina.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE9500081A BE1009071A3 (nl) 1995-02-02 1995-02-02 Werkwijze voor de bereiding van een beta-lactam antibioticum.

Publications (1)

Publication Number Publication Date
BE1009071A3 true BE1009071A3 (nl) 1996-11-05

Family

ID=3888755

Family Applications (1)

Application Number Title Priority Date Filing Date
BE9500081A BE1009071A3 (nl) 1995-02-02 1995-02-02 Werkwijze voor de bereiding van een beta-lactam antibioticum.

Country Status (5)

Country Link
EP (1) EP0815256A1 (fr)
AU (1) AU4846296A (fr)
BE (1) BE1009071A3 (fr)
IN (2) IN181940B (fr)
WO (1) WO1996023897A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1007302C2 (nl) * 1997-10-17 1999-04-20 Dsm Nv Werkwijze voor de bereiding van een ß-lactam antibioticum.
DE19823332C2 (de) * 1998-05-26 2000-09-07 Unifar Kimya Sanayii Ve Ticare Verfahren zur enzymatischen Herstellung von Betalactam-Antibiotika

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009136A1 (fr) * 1989-12-12 1991-06-27 Consejo Superior Investigaciones Cientificas Procede de synthese d'antibiotiques semi-synthetiques dans des systemes regules thermodynamiquement eau/cosolvants organiques miscibles apolaires par utilisation de penicilline g acylase
WO1992001061A1 (fr) * 1990-07-04 1992-01-23 Novo Nordisk A/S PROCEDE DE PREPARATION DE DERIVES DE β-LACTAMES

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009136A1 (fr) * 1989-12-12 1991-06-27 Consejo Superior Investigaciones Cientificas Procede de synthese d'antibiotiques semi-synthetiques dans des systemes regules thermodynamiquement eau/cosolvants organiques miscibles apolaires par utilisation de penicilline g acylase
WO1992001061A1 (fr) * 1990-07-04 1992-01-23 Novo Nordisk A/S PROCEDE DE PREPARATION DE DERIVES DE β-LACTAMES

Also Published As

Publication number Publication date
WO1996023897A1 (fr) 1996-08-08
IN182469B (fr) 1999-04-17
EP0815256A1 (fr) 1998-01-07
IN181940B (fr) 1998-11-14
AU4846296A (en) 1996-08-21

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: DSM N.V.

Effective date: 19970228