BE1002024A6 - Preparation medicamenteuse a base de derives d'esters d'hecogenine et leur utilisation pour le traitement de l'hyperplasie prostatique benigne. - Google Patents
Preparation medicamenteuse a base de derives d'esters d'hecogenine et leur utilisation pour le traitement de l'hyperplasie prostatique benigne. Download PDFInfo
- Publication number
- BE1002024A6 BE1002024A6 BE8900463A BE8900463A BE1002024A6 BE 1002024 A6 BE1002024 A6 BE 1002024A6 BE 8900463 A BE8900463 A BE 8900463A BE 8900463 A BE8900463 A BE 8900463A BE 1002024 A6 BE1002024 A6 BE 1002024A6
- Authority
- BE
- Belgium
- Prior art keywords
- hecogenin
- treatment
- derivatives
- esters
- benign prostatic
- Prior art date
Links
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 title 1
- QOLRLLFJMZLYQJ-LOBDNJQFSA-N Hecogenin Chemical class O([C@@H]1[C@@H]([C@]2(C(=O)C[C@@H]3[C@@]4(C)CC[C@H](O)C[C@@H]4CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@@H](C)CO1 QOLRLLFJMZLYQJ-LOBDNJQFSA-N 0.000 title 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- OXLGJTRVVNGJRK-UHFFFAOYSA-N Hecogenin Natural products CC1CCC2(CC3CC4C5CCC6CC(O)CCC6(C)C5CC(=O)C4(C)C3C2C)OC1 OXLGJTRVVNGJRK-UHFFFAOYSA-N 0.000 abstract 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- UVLDESQWQRMYKD-UHFFFAOYSA-N Neobotogenin Natural products CC1C(C2(C(=O)CC3C4(C)CCC(O)CC4=CCC3C2C2)C)C2OC11CCC(C)CO1 UVLDESQWQRMYKD-UHFFFAOYSA-N 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 230000001364 causal effect Effects 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 206010020718 hyperplasia Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3838716A DE3838716A1 (de) | 1988-11-15 | 1988-11-15 | Arzneimittelzubereitung aus esterderivaten des hecogenins und dessen verwendung zur behandlung von benigner prostatahyperplasie |
Publications (1)
Publication Number | Publication Date |
---|---|
BE1002024A6 true BE1002024A6 (fr) | 1990-05-22 |
Family
ID=6367236
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE8900463A BE1002024A6 (fr) | 1988-11-15 | 1989-04-26 | Preparation medicamenteuse a base de derives d'esters d'hecogenine et leur utilisation pour le traitement de l'hyperplasie prostatique benigne. |
BE8900463A BE1002504A3 (fr) | 1988-11-15 | 1989-04-26 | Preparation medicamenteuse a base de derives d'esters d'hecogenine et leur utilisation pour le traitement de l'hyperplasie prostatique benigne. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE8900463A BE1002504A3 (fr) | 1988-11-15 | 1989-04-26 | Preparation medicamenteuse a base de derives d'esters d'hecogenine et leur utilisation pour le traitement de l'hyperplasie prostatique benigne. |
Country Status (9)
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE314057T1 (de) * | 1998-03-26 | 2006-01-15 | Phytopharm Plc | Smilagenin und anzurogenin-d zur behandlung der alzheimerischen krankheit |
GB9923076D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
US6241987B1 (en) * | 1998-08-20 | 2001-06-05 | Amway Corporation | Dietary supplement containing saw palmetto, pumpkin seed, and nettle root |
GB9923078D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
GB9923077D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
US6261607B1 (en) * | 1999-10-19 | 2001-07-17 | Thomas Newmark | Composition for promoting prostate health containing selenium and herbal extracts |
GB0000228D0 (en) * | 2000-01-06 | 2000-03-01 | Phytopharm Plc | Fluoro substituted sapogenins and their use |
GB0107822D0 (en) * | 2001-03-28 | 2001-05-23 | Phytopharm Plc | Sapogenin derivatives their synthesis and use methods based upon their use |
US20050130948A1 (en) * | 2002-03-27 | 2005-06-16 | Daryl Rees | Therapeutic methods and uses of sapogenins and their derivatives |
KR101130212B1 (ko) * | 2002-03-27 | 2012-04-13 | 파이토팜 피엘씨 | 사포게닌 및 그 유도체의 치료 방법 및 사용법 |
US8258329B2 (en) | 2008-04-18 | 2012-09-04 | Reata Pharmaceuticals, Inc. | Dehydroandrosterone analogs including an anti-inflammatory pharmacore and methods of use |
WO2018042825A1 (ja) * | 2016-08-30 | 2018-03-08 | パナソニックIpマネジメント株式会社 | 色変換素子 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2201893A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1972-10-06 | 1974-05-03 | American Home Prod | |
DE2759171A1 (de) * | 1977-12-31 | 1979-07-12 | Roecar Holdings Nv | Arzneimittel mit wirkung als prostaglandinsynthetaseninhibitor |
GB2024624A (en) * | 1978-07-05 | 1980-01-16 | Roecar Holdings Nv | Anti inflammatory spiroketalins |
EP0285383A2 (en) * | 1987-04-03 | 1988-10-05 | Merck & Co. Inc. | Treatment of prostatic carcinoma with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA582813A (en) * | 1959-09-08 | Elks Joseph | 3.beta., 12.beta.-DIHYDROXY-11-OXO-23-BROMO-5.alpha., 22.alpha.-SPIROSTAN | |
US3935194A (en) * | 1974-01-22 | 1976-01-27 | Omni Research Incorporated | Separation of hecogenin-tigogenin mixtures |
DE2926463A1 (de) * | 1978-07-05 | 1980-01-24 | Roecar Holdings Nv | Spiroketaline und ihre verwendung |
-
1988
- 1988-11-15 DE DE3838716A patent/DE3838716A1/de active Granted
-
1989
- 1989-04-26 BE BE8900463A patent/BE1002024A6/xx active
- 1989-04-26 BE BE8900463A patent/BE1002504A3/fr not_active IP Right Cessation
- 1989-05-11 IT IT8920466A patent/IT1229272B/it active
- 1989-10-25 DE DE8989119837T patent/DE58904722D1/de not_active Expired - Fee Related
- 1989-10-25 EP EP89119837A patent/EP0369216B1/de not_active Expired - Lifetime
- 1989-10-25 ES ES89119837T patent/ES2057054T3/es not_active Expired - Lifetime
- 1989-10-25 AT AT89119837T patent/ATE90563T1/de not_active IP Right Cessation
- 1989-11-13 US US07/434,344 patent/US5002939A/en not_active Expired - Lifetime
- 1989-11-15 JP JP1297266A patent/JP2562210B2/ja not_active Expired - Fee Related
-
1993
- 1993-06-17 GR GR930400367T patent/GR3008170T3/el unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2201893A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1972-10-06 | 1974-05-03 | American Home Prod | |
DE2759171A1 (de) * | 1977-12-31 | 1979-07-12 | Roecar Holdings Nv | Arzneimittel mit wirkung als prostaglandinsynthetaseninhibitor |
GB2024624A (en) * | 1978-07-05 | 1980-01-16 | Roecar Holdings Nv | Anti inflammatory spiroketalins |
EP0285383A2 (en) * | 1987-04-03 | 1988-10-05 | Merck & Co. Inc. | Treatment of prostatic carcinoma with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones |
Also Published As
Publication number | Publication date |
---|---|
ATE90563T1 (de) | 1993-07-15 |
US5002939A (en) | 1991-03-26 |
DE3838716A1 (de) | 1990-05-17 |
GR3008170T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-09-30 |
DE3838716C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-09-20 |
JPH02180830A (ja) | 1990-07-13 |
DE58904722D1 (de) | 1993-07-22 |
EP0369216B1 (de) | 1993-06-16 |
ES2057054T3 (es) | 1994-10-16 |
BE1002504A3 (fr) | 1991-03-05 |
IT1229272B (it) | 1991-07-26 |
JP2562210B2 (ja) | 1996-12-11 |
EP0369216A3 (en) | 1990-11-07 |
EP0369216A2 (de) | 1990-05-23 |
IT8920466A0 (it) | 1989-05-11 |
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