ITMI921559A0 - Esteri amminoalchilcarbanici dell'eserolina atti all'impiego come anticolinesterasici e relativo procedimento di preparazione - Google Patents

Esteri amminoalchilcarbanici dell'eserolina atti all'impiego come anticolinesterasici e relativo procedimento di preparazione

Info

Publication number
ITMI921559A0
ITMI921559A0 IT92MI1559A ITMI921559A ITMI921559A0 IT MI921559 A0 ITMI921559 A0 IT MI921559A0 IT 92MI1559 A IT92MI1559 A IT 92MI1559A IT MI921559 A ITMI921559 A IT MI921559A IT MI921559 A0 ITMI921559 A0 IT MI921559A0
Authority
IT
Italy
Prior art keywords
aminoalkylcarbanic
eserolin
anticholinesterases
esters
preparation procedure
Prior art date
Application number
IT92MI1559A
Other languages
English (en)
Inventor
Mario Brufani
Sperandina Lappa
Pier Giuseppe Pagella
Stefano Maiorana
Donata Marchesini
Maria Alessandra Alisi
Maria Candida Cesta
Luigi Filocamo
Gianluca Gostoli
Enrico Ferrari
Original Assignee
Mediolanum Farmaceutici Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farmaceutici Srl filed Critical Mediolanum Farmaceutici Srl
Publication of ITMI921559A0 publication Critical patent/ITMI921559A0/it
Priority to ITMI921559A priority Critical patent/IT1254996B/it
Priority to EP93109932A priority patent/EP0575954B1/en
Priority to DE69320705T priority patent/DE69320705D1/de
Priority to AT93109932T priority patent/ATE170522T1/de
Priority to US08/079,921 priority patent/US5302593A/en
Priority to KR1019930011626A priority patent/KR940005627A/ko
Priority to JP5175912A priority patent/JPH06206882A/ja
Priority to CA002099648A priority patent/CA2099648A1/en
Publication of ITMI921559A1 publication Critical patent/ITMI921559A1/it
Priority to US08/177,325 priority patent/US5424451A/en
Application granted granted Critical
Publication of IT1254996B publication Critical patent/IT1254996B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
ITMI921559A 1992-06-25 1992-06-25 Esteri amminoalchilcarbammici dell'eserolina atti all'impiego come anticolinesterasici e relativo procedimento di preparazione IT1254996B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ITMI921559A IT1254996B (it) 1992-06-25 1992-06-25 Esteri amminoalchilcarbammici dell'eserolina atti all'impiego come anticolinesterasici e relativo procedimento di preparazione
EP93109932A EP0575954B1 (en) 1992-06-25 1993-06-22 Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process
DE69320705T DE69320705D1 (de) 1992-06-25 1993-06-22 Aminoalkylcarbamatester von Eserolin verwendbar als Inhibitoren von Cholinesteraseaktivität und Verfahren zu deren Herstellung
AT93109932T ATE170522T1 (de) 1992-06-25 1993-06-22 Aminoalkylcarbamatester von eserolin verwendbar als inhibitoren von cholinesteraseaktivität und verfahren zu deren herstellung
US08/079,921 US5302593A (en) 1992-06-25 1993-06-23 Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors
KR1019930011626A KR940005627A (ko) 1992-06-25 1993-06-24 콜린에스테라제 활성 저해제로서 적합한 에제롤린의 아미노알킬카르밤산 에스테르 및 이의 제조방법
JP5175912A JPH06206882A (ja) 1992-06-25 1993-06-24 コリンエステラーゼ活性インヒビターとしての使用に適したエセロリンのアミノアルキルカルバミンエステル及びその調製法
CA002099648A CA2099648A1 (en) 1992-06-25 1993-06-24 Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase activity inhibitors and relative preparation process
US08/177,325 US5424451A (en) 1992-06-25 1994-01-04 Process for preparing aminoalkylcarbamic esters of eseroline

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI921559A IT1254996B (it) 1992-06-25 1992-06-25 Esteri amminoalchilcarbammici dell'eserolina atti all'impiego come anticolinesterasici e relativo procedimento di preparazione

Publications (3)

Publication Number Publication Date
ITMI921559A0 true ITMI921559A0 (it) 1992-06-25
ITMI921559A1 ITMI921559A1 (it) 1993-12-25
IT1254996B IT1254996B (it) 1995-10-11

Family

ID=11363576

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI921559A IT1254996B (it) 1992-06-25 1992-06-25 Esteri amminoalchilcarbammici dell'eserolina atti all'impiego come anticolinesterasici e relativo procedimento di preparazione

Country Status (8)

Country Link
US (2) US5302593A (it)
EP (1) EP0575954B1 (it)
JP (1) JPH06206882A (it)
KR (1) KR940005627A (it)
AT (1) ATE170522T1 (it)
CA (1) CA2099648A1 (it)
DE (1) DE69320705D1 (it)
IT (1) IT1254996B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133444A (en) 1993-12-22 2000-10-17 Perseptive Biosystems, Inc. Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions
IT1271679B (it) * 1994-07-18 1997-06-04 Mediolanum Farmaceutici Srl Derivati del fenilcarbammato atti all'impiego come anticolinesterasici
JP2001518054A (ja) * 1995-06-07 2001-10-09 パーセプティブ バイオシステムズ，インコーポレーテッド Ｐｎａ−ｄｎａキメラと、このキメラ合成用のｐｎａシントン
US5952506A (en) * 1997-04-24 1999-09-14 American Home Products Corporation Process for the synthesis of 4- 6- (hexylcarbamoyloxy) hexylcarbamoyloxy!-piperidine-1-carboxylic acid 4-phenoxyphenyl ester
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
EA037187B1 (ru) 2010-02-09 2021-02-17 Дзе Джонс Хопкинс Юниверсити Способ и композиция для лечения когнитивного расстройства
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
US11160785B2 (en) 2013-03-15 2021-11-02 Agenebio Inc. Methods and compositions for improving cognitive function
EP2968237A4 (en) 2013-03-15 2016-08-31 Univ Johns Hopkins METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
AU2016268096B2 (en) 2015-05-22 2021-04-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
EP0513703A3 (en) * 1991-05-13 1993-01-13 Magis Farmaceutici S.P.A. Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle

Also Published As

Publication number Publication date
US5302593A (en) 1994-04-12
JPH06206882A (ja) 1994-07-26
IT1254996B (it) 1995-10-11
ITMI921559A1 (it) 1993-12-25
DE69320705D1 (de) 1998-10-08
KR940005627A (ko) 1994-03-22
ATE170522T1 (de) 1998-09-15
US5424451A (en) 1995-06-13
CA2099648A1 (en) 1993-12-26
EP0575954B1 (en) 1998-09-02
EP0575954A1 (en) 1993-12-29

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970627