AU9223198A - Mammalian chk1 effector cell-cycle checkpoint protein kinase materials and methods - Google Patents

Mammalian chk1 effector cell-cycle checkpoint protein kinase materials and methods Download PDF

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Publication number
AU9223198A
AU9223198A AU92231/98A AU9223198A AU9223198A AU 9223198 A AU9223198 A AU 9223198A AU 92231/98 A AU92231/98 A AU 92231/98A AU 9223198 A AU9223198 A AU 9223198A AU 9223198 A AU9223198 A AU 9223198A
Authority
AU
Australia
Prior art keywords
chkl
dna
kinase
cell
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU92231/98A
Other languages
English (en)
Inventor
Antony Michael Carr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Icos Corp
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Publication of AU9223198A publication Critical patent/AU9223198A/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU92231/98A 1997-09-05 1998-09-04 Mammalian chk1 effector cell-cycle checkpoint protein kinase materials and methods Abandoned AU9223198A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9718952 1997-09-05
GBGB9718952.6A GB9718952D0 (en) 1997-09-05 1997-09-05 Mammalian chk1 effector cell cycle checkpoint protein kinase materials and methods
PCT/US1998/018558 WO1999011795A1 (fr) 1997-09-05 1998-09-04 Materiels de proteine-kinase point de controle du cycle cellulaire, effecteur de chk1 mammalien et methodes

Publications (1)

Publication Number Publication Date
AU9223198A true AU9223198A (en) 1999-03-22

Family

ID=10818664

Family Applications (1)

Application Number Title Priority Date Filing Date
AU92231/98A Abandoned AU9223198A (en) 1997-09-05 1998-09-04 Mammalian chk1 effector cell-cycle checkpoint protein kinase materials and methods

Country Status (7)

Country Link
EP (1) EP0960203A1 (fr)
JP (1) JP2002516577A (fr)
CN (1) CN1254377A (fr)
AU (1) AU9223198A (fr)
CA (1) CA2270911A1 (fr)
GB (2) GB9718952D0 (fr)
WO (1) WO1999011795A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071691A (en) * 1998-04-27 2000-06-06 Oregon Health Science University Materials and methods for modulating differentiation
US6723498B1 (en) * 1999-06-30 2004-04-20 Millennium Pharmaceuticals, Inc. Chk1 and uses thereof
AU5874000A (en) 1999-07-29 2001-02-19 Wistar Institute Of Anatomy And Biology, The Compositions and methods to enhance sensitivity of cancer cells to mitotic stress
US6670167B1 (en) * 1999-11-01 2003-12-30 Agouron Pharmaceuticals, Inc. Catalytic domain of the human effector cell cycle checkpoint protein kinase materials and methods for identification of inhibitors thereof
JP2003517297A (ja) * 1999-09-23 2003-05-27 ライジェル・ファーマシューティカルズ・インコーポレイテッド チェックポイント遺伝子関連細胞周期タンパク質、組成物および使用法
IL132446A0 (en) * 1999-10-18 2001-03-19 Genena Ltd A method for establishing connections between genes
WO2001057206A2 (fr) * 2000-02-03 2001-08-09 Ribozyme Pharmaceuticals, Inc. Procede et reactif destines a inhiber la checkpoint kinase-1 (chk 1)
US6211164B1 (en) * 2000-03-10 2001-04-03 Abbott Laboratories Antisense oligonucleotides of the human chk1 gene and uses thereof
WO2004004785A1 (fr) * 2002-07-10 2004-01-15 Exelixis, Inc. Agents mchk modificateurs de la voie metabolique de chk1 et procedes d'utilisation
WO2005027907A1 (fr) * 2003-09-17 2005-03-31 Icos Corporation Utilisation d'inhibiteurs de la chk1 pour lutter contre la proliferation cellulaire
EP1869020B1 (fr) 2005-03-29 2010-12-01 ICOS Corporation Derives d'uree d'heteroaryle utilises pour inhiber chk1
DE102006054292A1 (de) * 2006-11-17 2009-01-08 Universität Duisburg-Essen Verwendung von Genveränderungen im menschlichen Gen CHK1, das für die Checkpointkinase 1 kodiert

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9518220D0 (en) * 1995-09-06 1995-11-08 Medical Res Council Checkpoint gene
AU1461197A (en) * 1995-11-16 1997-06-05 Icos Corporation Cell cycle checkpoint pik-related kinase materials and methods

Also Published As

Publication number Publication date
GB9718952D0 (en) 1997-11-12
WO1999011795A1 (fr) 1999-03-11
EP0960203A1 (fr) 1999-12-01
CA2270911A1 (fr) 1999-03-11
GB9723231D0 (en) 1998-01-07
JP2002516577A (ja) 2002-06-04
CN1254377A (zh) 2000-05-24

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted