AU8506601A - Binding polypeptides for b lymphocyte stimulator protein (blys) - Google Patents

Binding polypeptides for b lymphocyte stimulator protein (blys)

Info

Publication number
AU8506601A
AU8506601A AU8506601A AU8506601A AU8506601A AU 8506601 A AU8506601 A AU 8506601A AU 8506601 A AU8506601 A AU 8506601A AU 8506601 A AU8506601 A AU 8506601A AU 8506601 A AU8506601 A AU 8506601A
Authority
AU
Australia
Prior art keywords
blys
binding polypeptides
lymphocyte stimulator
polypeptides
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU8506601A
Other languages
English (en)
Inventor
James P Beltzer
M Daniel Potter
Tony J Fleming
Robert Charles Ladner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dyax Corp
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp filed Critical Dyax Corp
Publication of AU8506601A publication Critical patent/AU8506601A/xx
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU8506601A 2000-08-18 2001-08-17 Binding polypeptides for b lymphocyte stimulator protein (blys) Pending AU8506601A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22648900P 2000-08-18 2000-08-18
PCT/US2001/025891 WO2002016412A2 (en) 2000-08-18 2001-08-17 Binding polypeptides for b lymphocyte stimulator protein (blys)

Publications (1)

Publication Number Publication Date
AU8506601A true AU8506601A (en) 2002-03-04

Family

ID=22849104

Family Applications (2)

Application Number Title Priority Date Filing Date
AU8506601A Pending AU8506601A (en) 2000-08-18 2001-08-17 Binding polypeptides for b lymphocyte stimulator protein (blys)
AU2001285066A Ceased AU2001285066B2 (en) 2000-08-18 2001-08-17 Binding polypeptides for B lymphocyte stimulator protein (BLYS)

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001285066A Ceased AU2001285066B2 (en) 2000-08-18 2001-08-17 Binding polypeptides for B lymphocyte stimulator protein (BLYS)

Country Status (8)

Country Link
US (1) US7118872B2 (enExample)
EP (11) EP2267015A3 (enExample)
JP (2) JP2004532604A (enExample)
AT (1) ATE451390T1 (enExample)
AU (2) AU8506601A (enExample)
CA (1) CA2418006A1 (enExample)
DE (1) DE60140773D1 (enExample)
WO (1) WO2002016412A2 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8212004B2 (en) * 1999-03-02 2012-07-03 Human Genome Sciences, Inc. Neutrokine-alpha fusion proteins
US6812327B1 (en) * 1996-10-25 2004-11-02 Human Genome Sciences, Inc. Neutrokine-alpha polypeptides
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
US20050100548A1 (en) * 2001-07-24 2005-05-12 Biogen Idec Ma Inc. BAFF, inhibitors thereof and their use in the modulation of B-cell response
US20030095967A1 (en) * 1999-01-25 2003-05-22 Mackay Fabienne BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders
PT1255558E (pt) * 2000-02-16 2006-11-30 Genentech Inc Anticorpos anti-april e células hibridoma
US7879328B2 (en) * 2000-06-16 2011-02-01 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to B lymphocyte stimulator
EP2275449B1 (en) * 2000-06-16 2016-09-28 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to BLyS
US20030091565A1 (en) 2000-08-18 2003-05-15 Beltzer James P. Binding polypeptides and methods based thereon
UA83458C2 (uk) * 2000-09-18 2008-07-25 Байоджен Айдек Ма Інк. Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
ES2387546T3 (es) 2001-05-11 2012-09-25 Amgen Inc. Péptidos y moléculas relacionadas que se unen a TALL-1
KR20040019105A (ko) * 2001-08-03 2004-03-04 제넨테크, 인크. ＴＡＣＩｓ 및 ＢＲ3 폴리펩티드 및 이의 용도
US7825089B2 (en) 2001-10-24 2010-11-02 National Jewish Health Three-dimensional structures of TALL-1 and its cognate receptors and modified proteins and methods related thereto
US20080267965A1 (en) * 2002-02-21 2008-10-30 Kalled Susan L Use of Bcma as an Immunoregulatory Agent
EP1587944A4 (en) 2002-03-01 2007-03-21 Dyax Corp KDR AND VEGF / KDR BINDING PEPTIDES AND THEIR USE FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
EP2014310B8 (en) * 2002-03-01 2012-12-26 Dyax Corp. KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
AU2003256836A1 (en) * 2002-07-25 2004-02-16 Genentech, Inc. Taci antibodies and uses thereof
AU2004233164B2 (en) 2003-03-28 2009-10-08 Biogen Ma Inc. Truncated BAFF receptors
EP2272868B1 (en) * 2003-06-05 2015-03-04 Genentech, Inc. Combination therapy for B cell disorders
US20050163775A1 (en) * 2003-06-05 2005-07-28 Genentech, Inc. Combination therapy for B cell disorders
CN100378122C (zh) * 2004-12-03 2008-04-02 中国人民解放军第三军医大学 B淋巴细胞刺激因子抑制肽及其制备方法
EA015860B1 (ru) * 2005-10-13 2011-12-30 Хьюман Дженом Сайенсиз, Инк. Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа
US9168286B2 (en) * 2005-10-13 2015-10-27 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive disease
CA2629306A1 (en) 2005-11-23 2007-05-31 Genentech, Inc. Methods and compositions related to b cell assays
US8211649B2 (en) 2006-03-31 2012-07-03 Human Genome Sciences, Inc. Methods of diagnosing and prognosing hodgkin's lymphoma
WO2010075249A2 (en) 2008-12-22 2010-07-01 Genentech, Inc. A method for treating rheumatoid arthritis with b-cell antagonists
WO2010093993A2 (en) * 2009-02-12 2010-08-19 Human Genome Sciences, Inc. Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance
MX353186B (es) 2009-09-03 2018-01-05 Genentech Inc Metodos para el tratamiento, diagnosis y monitoreo de artritis reumatoide.
CN103502472B (zh) 2011-02-28 2017-06-06 弗·哈夫曼-拉罗切有限公司 生物标记物和用于预测对b‑细胞拮抗剂的响应的方法
JP2013040148A (ja) * 2011-08-19 2013-02-28 Asahi Kasei Corp シアリルオリゴ糖ペプチド固定化ビーズ
US9458246B2 (en) 2013-03-13 2016-10-04 Amgen Inc. Proteins specific for BAFF and B7RP1
PH12022550138A1 (en) 2013-03-13 2023-03-06 Amgen Inc Proteins specific for baff and b7rp1 and uses thereof
WO2018026742A1 (en) * 2016-08-01 2018-02-08 Askgene Pharma Inc. Novel antibody-albumin-drug conjugates (aadc) and methods for using them

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1195987B (de) 1962-02-05 1965-07-01 Siemens Ag Foerdereinrichtung fuer kartenfoermige Aufzeichnungstraeger
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4002531A (en) 1976-01-22 1977-01-11 Pierce Chemical Company Modifying enzymes with polyethylene glycol and product produced thereby
US5576195A (en) 1985-11-01 1996-11-19 Xoma Corporation Vectors with pectate lyase signal sequence
CN1033030C (zh) 1988-06-24 1996-10-16 唐化学原料公司 大环双官能螯合剂及其配合物和抗体共轭物的制备方法
US5756065A (en) 1988-06-24 1998-05-26 The Dow Chemical Company Macrocyclic tetraazacyclododecane conjugates and their use as diagnostic and therapeutic agents
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5349052A (en) 1988-10-20 1994-09-20 Royal Free Hospital School Of Medicine Process for fractionating polyethylene glycol (PEG)-protein adducts and an adduct for PEG and granulocyte-macrophage colony stimulating factor
EP0401384B1 (en) 1988-12-22 1996-03-13 Kirin-Amgen, Inc. Chemically modified granulocyte colony stimulating factor
US5198346A (en) 1989-01-06 1993-03-30 Protein Engineering Corp. Generation and selection of novel DNA-binding proteins and polypeptides
US5096815A (en) 1989-01-06 1992-03-17 Protein Engineering Corporation Generation and selection of novel dna-binding proteins and polypeptides
US5324844A (en) 1989-04-19 1994-06-28 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
CA2067194C (en) 1989-10-05 2003-03-18 Glenn Kawasaki Cell-free synthesis and isolation of novel genes and polypeptides
US5314995A (en) 1990-01-22 1994-05-24 Oncogen Therapeutic interleukin-2-antibody based fusion proteins
US5747334A (en) 1990-02-15 1998-05-05 The University Of North Carolina At Chapel Hill Random peptide library
GB9119270D0 (en) * 1991-10-09 1991-10-23 Seetru Ltd A novel design for a reflex flat glass type liquid level gauge
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
ZA932522B (en) 1992-04-10 1993-12-20 Res Dev Foundation Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
EP0749475A4 (en) 1992-08-26 1997-05-07 Harvard College USE OF CYTOKINE IP-10 AS ANTI-TUMOR AGENT
US5869331A (en) 1992-11-20 1999-02-09 University Of Medicine & Dentistry Of New Jersey Cell type specific gene transfer using retroviral vectors containing antibody-envelope fusion proteins and wild-type envelope fusion proteins
GB9317618D0 (en) 1993-08-24 1993-10-06 Royal Free Hosp School Med Polymer modifications
US5643575A (en) 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
WO1998029747A1 (en) * 1994-11-23 1998-07-09 Abbott Laboratories Reagents and methods for detecting hepatitis gb virus antigen
US5874409A (en) * 1995-06-07 1999-02-23 La Jolla Pharmaceutical Company APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies
JP2000512981A (ja) 1996-06-06 2000-10-03 ラ ホヤ ファーマシューティカル カンパニー ａＰＬ免疫応答性ペプチド、その結合体およびａＰＬ抗体媒介病理のための処置方法
EP0921817B1 (en) 1997-01-29 2001-03-28 PolyMASC Pharmaceuticals plc Pegylation process
EP1798288B1 (en) * 1997-05-07 2009-09-16 Schering Corporation Human Toll-like receptor proteins, related reagents and methods
US5795724A (en) * 1997-09-12 1998-08-18 Incyte Pharmaceuticals, Inc. Human N-acetyl transferase
WO1999058558A2 (en) * 1998-05-13 1999-11-18 Incyte Pharmaceuticals, Inc. Cell signaling proteins
DE19829785A1 (de) 1998-07-03 2000-01-05 Henkel Kgaa Verwendung
DE60005135T3 (de) * 1999-01-07 2015-04-09 Zymogenetics, Inc. Lösliche rezeptoren br43x2 und verfahren zu deren therapeutischen verwendung
CA2360062A1 (en) 1999-01-25 2000-07-27 Biogen, Inc. Baff, inhibitors thereof and their use in the modulation of b-cell response
US6475986B1 (en) * 1999-02-02 2002-11-05 Research Development Foundation Uses of THANK, a TNF homologue that activates apoptosis
AU3395900A (en) * 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
CA2404945C (en) 2000-04-27 2010-02-09 Biogen, Inc. Taci as an anti-tumor agent
CA2408617A1 (en) 2000-05-12 2001-11-22 Amgen Inc. Methods and compositions of matter concerning april/g70, bcma, blys/agp-3, and taci
EP2275449B1 (en) * 2000-06-16 2016-09-28 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to BLyS
UA83458C2 (uk) 2000-09-18 2008-07-25 Байоджен Айдек Ма Інк. Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
ES2387546T3 (es) 2001-05-11 2012-09-25 Amgen Inc. Péptidos y moléculas relacionadas que se unen a TALL-1
DK1436003T3 (da) 2001-05-24 2010-03-15 Zymogenetics Inc TACI-immunoglobulin-fusionsproteiner
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents

Also Published As

Publication number Publication date
EP1674477A3 (en) 2007-02-28
EP1674477B1 (en) 2009-12-09
EP2267020A2 (en) 2010-12-29
ATE451390T1 (de) 2009-12-15
EP2270040A2 (en) 2011-01-05
JP2012131816A (ja) 2012-07-12
EP2267018A3 (en) 2011-04-20
EP2267018A2 (en) 2010-12-29
WO2002016412A3 (en) 2003-06-26
EP2267017A3 (en) 2011-07-06
EP2261246A3 (en) 2011-07-13
EP2184291A1 (en) 2010-05-12
EP2267019A2 (en) 2010-12-29
EP2267019A3 (en) 2011-07-06
EP2267016A3 (en) 2011-04-20
EP1339746A2 (en) 2003-09-03
EP2267015A2 (en) 2010-12-29
EP2261246A2 (en) 2010-12-15
EP2267015A3 (en) 2011-04-20
US20030194743A1 (en) 2003-10-16
DE60140773D1 (de) 2010-01-21
WO2002016412A2 (en) 2002-02-28
EP2267020A3 (en) 2011-04-20
EP1674477A2 (en) 2006-06-28
CA2418006A1 (en) 2002-02-28
US7118872B2 (en) 2006-10-10
JP2004532604A (ja) 2004-10-28
EP2270040A3 (en) 2011-07-06
EP2267017A2 (en) 2010-12-29
EP2267016A2 (en) 2010-12-29
AU2001285066B2 (en) 2006-06-29

Similar Documents

Publication Publication Date Title
AU8506601A (en) Binding polypeptides for b lymphocyte stimulator protein (blys)
DK1434791T3 (da) Specifikke bindingsmidler til human angiopoietin-2
WO2002032925A3 (en) Protein scaffolds for antibody mimics and other binding proteins
HUP0100025A3 (en) Methods for treating hypercoagulable states or acquired protein c deficiency
AU7473500A (en) Identification of peptides that facilitate uptake and cytoplasmic and/or nucleartransport of proteins, dna and viruses
MXPA02012743A (es) Moleculas tipo il-17 y usos de las mismas.
PT1705183E (pt) Moléculas de ligação para o factor viii humano e proteínas de tipo factor viii
WO2002004949A3 (en) Reagents and methods for identification of binding agents
FR2816410B1 (fr) Necessaire de detection de la proteine esm-1 et procede de detection mettant en oeuvre ledit necessaire
DE60230312D1 (de) Verfahren zur proteinreinigung
EP1243923A4 (en) METHOD FOR SELECTING A CANCER REMEDY USING P53 AND MORTALIN INTERACTION AREAS
MXPA01008605A (es) Proteina de enlace del antigeno goodpasture.
WO2003068940A3 (en) Complexes and methods of using same
MXPA04002103A (es) Una proteina de union a caspasa-8, su preparacion y uso.
SE9002213D0 (sv) Albumin binding proteins
WO2002036766A3 (en) Protein-protein complexes and methods of using same
EP1627063A4 (en) INDUCTION OF FLOWER
WO2005017109A3 (en) Nucleic acids and polypeptides required for cell survival in the absence of rb
AU2002336837A1 (en) Methods and apparatus for protein sequence analysis
WO2007026171A8 (en) Vdcc gamma-8 ion channel
WO2003006496A3 (fr) Variants proteiques de la neocarzinostatine et de ses homologues et leur utilisation
TH43074A (th) โปรตีนเชื่อมกลูโคสดีไฮโดรจีเนส และการใช้ของมันในระบบการแสดงลักษณะ
AU2002323866A1 (en) Method for separating, purifying and identifying proteins from protein mixtures
AU2001273396A1 (en) Methods for stabilizing lyophilized blood proteins