AU8154398A - Cloning using donor nuclei from non-serum starved, differentiated cells - Google Patents

Cloning using donor nuclei from non-serum starved, differentiated cells Download PDF

Info

Publication number
AU8154398A
AU8154398A AU81543/98A AU8154398A AU8154398A AU 8154398 A AU8154398 A AU 8154398A AU 81543/98 A AU81543/98 A AU 81543/98A AU 8154398 A AU8154398 A AU 8154398A AU 8154398 A AU8154398 A AU 8154398A
Authority
AU
Australia
Prior art keywords
cells
cell
disease
differentiated
offspring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU81543/98A
Other languages
English (en)
Inventor
Jose Cibelli
Paul Golueke
D. Joseph Jerry
F. Abel Ponce De Leon
James M. Robl
Steven L. Stice
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Massachusetts UMass
Original Assignee
University of Massachusetts UMass
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Massachusetts UMass filed Critical University of Massachusetts UMass
Publication of AU8154398A publication Critical patent/AU8154398A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877Techniques for producing new mammalian cloned embryos
    • C12N15/8771Bovine embryos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00Cells related to new breeds of animals
    • C12N2517/02Cells from transgenic animals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00Cells related to new breeds of animals
    • C12N2517/04Cells produced using nuclear transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Psychology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
AU81543/98A 1997-01-10 1998-06-24 Cloning using donor nuclei from non-serum starved, differentiated cells Abandoned AU8154398A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/781752 1997-01-10
US88828397A 1997-07-03 1997-07-03
US08888283 1997-07-03
PCT/US1998/012800 WO1999001163A1 (fr) 1997-07-03 1998-06-24 Clonage a l'aide de noyaux donneurs a partir de cellules differentiees ne presentant pas de carence serique

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU60145/98A Division AU742363C (en) 1997-01-10 1998-01-05 Nuclear transfer with differentiated fetal and adult donor cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2002301114A Division AU2002301114A1 (en) 1997-01-10 2002-09-20 Cloning using donor nuclei from non-serum starved, differentiated cells

Publications (1)

Publication Number Publication Date
AU8154398A true AU8154398A (en) 1999-01-25

Family

ID=25392916

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81543/98A Abandoned AU8154398A (en) 1997-01-10 1998-06-24 Cloning using donor nuclei from non-serum starved, differentiated cells

Country Status (9)

Country Link
EP (1) EP1017422A4 (fr)
JP (1) JP2001509361A (fr)
CN (2) CN1265599A (fr)
AU (1) AU8154398A (fr)
BR (1) BR9811657A (fr)
CA (1) CA2294916A1 (fr)
IL (1) IL133786A0 (fr)
NZ (1) NZ502129A (fr)
WO (1) WO1999001163A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235969B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
CA2259368C (fr) * 1998-01-16 2010-10-05 Agrobiogen Gmbh Transfert de noyau efficace avec des fibroblastes de foetus
US6331659B1 (en) 1998-01-21 2001-12-18 University Of Hawaii Cumulus cells as nuclear donors
JP2002511234A (ja) * 1998-03-16 2002-04-16 リレグ ピーティーワイ リミテッド ブタの核移植
AUPP294898A0 (en) * 1998-04-15 1998-05-07 Monash University Method of nuclear transfer
WO2000025578A2 (fr) * 1999-04-26 2000-05-11 Trustees Of Tufts College Procedes de clonage des animaux
US6781030B1 (en) 1998-11-02 2004-08-24 Trustee Of Tufts College, Ballou Hall Methods for cloning mammals using telophase oocytes
EP1375654A3 (fr) * 1998-11-02 2008-01-16 GTC Biotherapeutics, Inc. Mammifères trangéniques et clonés
EP1818397A1 (fr) * 1998-11-02 2007-08-15 Trustees Of Tufts College Procéde pour le clonage des animaux
ATE452973T1 (de) 1999-03-04 2010-01-15 Revivicor Inc Genetische veränderung von somatischen zellen und deren verwendungen
AU753209B2 (en) * 1999-06-30 2002-10-10 Seoul National University Industry Foundation Method for producing cloned tigers by employing inter-species nuclear transplantation technique
JP2003503044A (ja) * 1999-06-30 2003-01-28 ワン,ウー−サク 種間核移植技術を用いたヒトクローン胚の作製方法
US6590139B1 (en) * 1999-06-30 2003-07-08 Woo-Suk Hwang Method for producing cloned cows
BR0014864A (pt) * 1999-10-15 2002-11-19 Advanced Cell Tech Inc Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagem
US7253334B2 (en) * 2000-12-22 2007-08-07 Aurox, Llc Methods for cloning non-human mammals using reprogrammed donor chromatin or donor cells
WO2001094554A1 (fr) * 2000-06-08 2001-12-13 Trostner, Jens Procede de reconstruction genetique d'organes humains
AU8470301A (en) 2000-08-03 2002-02-18 Wim-Van Schooten Production of humanized antibodies in transgenic animals
FR2814642B1 (fr) 2000-10-03 2005-07-01 Ass Pour Le Dev De La Rech En Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee
CN100422315C (zh) * 2000-11-30 2008-10-01 斯坦姆荣公司 分离的纯合干细胞,由其衍生的分化细胞,以及制备和使用上述细胞的材料和方法
ATE466089T1 (de) 2000-12-22 2010-05-15 Agronomique Inst Nat Rech Positionsunabhängige und gewebespezifische expression eines transgens in der milch eines transgen-tieres
EP1425386A4 (fr) 2001-08-13 2007-05-02 Embrex Inc Techniques d'injection sur des oeufs aviaires
JP2005528095A (ja) * 2002-04-01 2005-09-22 ジーティーシー バイオセラピューティックス インコーポレイテッド 哺乳類種における核移植に使用するための細胞株を選択する方法
US7612250B2 (en) 2002-07-29 2009-11-03 Trustees Of Tufts College Nuclear transfer embryo formation method
CN102719444B (zh) 2006-09-01 2016-12-14 人类多细胞株治疗学公司 人或人源化免疫球蛋白在非人转基因动物中增强的表达
EP2267153A1 (fr) 2009-05-26 2010-12-29 Université Claude Bernard Lyon 1 Identification de la mutation du gène unc5c du récepteur de la nétrine-1 dans des cancers solides
WO2013010045A1 (fr) 2011-07-12 2013-01-17 Biotime Inc. Nouveaux procédés et formulations pour thérapie cellulaire orthopédique

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0739412B1 (fr) * 1993-12-23 2002-02-27 Infigen, Inc. CELLULES d'ongules, SOUCHES D'EMBRYONS UTILISEES COMME DONNEUSES DE NOYAUX ET PROCEDES DE TRANSFERT DE NOYAUX POUR LA PRODUCTION D'ANIMAUX CHIMERIQUES ET TRANSGENIQUES
GB9517780D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517779D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
US5945577A (en) 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
CA2259368C (fr) * 1998-01-16 2010-10-05 Agrobiogen Gmbh Transfert de noyau efficace avec des fibroblastes de foetus

Also Published As

Publication number Publication date
EP1017422A1 (fr) 2000-07-12
CA2294916A1 (fr) 1999-01-14
WO1999001163A1 (fr) 1999-01-14
EP1017422A4 (fr) 2002-10-29
BR9811657A (pt) 2000-09-05
IL133786A0 (en) 2001-04-30
NZ502129A (en) 2005-02-25
JP2001509361A (ja) 2001-07-24
CN1265599A (zh) 2000-09-06
CN101003800A (zh) 2007-07-25

Similar Documents

Publication Publication Date Title
CA2277192C (fr) Transfert nucleaire au moyen de cellules donneuses foetales et adultes differentiees
US6235969B1 (en) Cloning pigs using donor nuclei from non-quiescent differentiated cells
AU740709B2 (en) Embryonic or stem-like cell lines produced by cross species nuclear transplanta tion
US6215041B1 (en) Cloning using donor nuclei from a non-quiesecent somatic cells
AU8154398A (en) Cloning using donor nuclei from non-serum starved, differentiated cells
US20010012513A1 (en) Embryonic or stem-like cell lines produced by cross species nuclear transplantation
CA2381124A1 (fr) Clonage de porcs a l'aide de cellules ou de noyaux de donneurs provenant de cellules differenciees et production de porcins multipotents
US20050095704A1 (en) Embryonic or stem-like cell lines produced by cross species nuclear transplantation
AU2006202185A1 (en) Cloning using donor nuclei from non-serum starved, differentiated cells
AU2011202964A1 (en) Nuclear transfer with differentiated fetal and adult donor cells
AU2006236032A1 (en) Nuclear transfer with differentiated fetal and adult donor cells
MXPA00000201A (en) Cloning using donor nuclei from non-serum starved, differentiated cells
MXPA99006464A (en) Nuclear transfer with differentiated fetal and adult donor cells
AU2005225075A1 (en) Cloning pigs using donor cells or nuclei from differentiated cells and production of pluripotent porcine

Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND APPLICATION TO CONVERT TO DIVISIONAL OF 60145/98

MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted