AU7702281A - 1-carboxy-azaalkanoylindoline-2-carboxylic acids - Google Patents

1-carboxy-azaalkanoylindoline-2-carboxylic acids

Info

Publication number
AU7702281A
AU7702281A AU77022/81A AU7702281A AU7702281A AU 7702281 A AU7702281 A AU 7702281A AU 77022/81 A AU77022/81 A AU 77022/81A AU 7702281 A AU7702281 A AU 7702281A AU 7702281 A AU7702281 A AU 7702281A
Authority
AU
Australia
Prior art keywords
azaalkanoylindoline
carboxy
carboxylic acids
carboxylic
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU77022/81A
Other languages
English (en)
Inventor
Harris Burt Renfroe
Alex Sele
James L. Stanton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU7702281A publication Critical patent/AU7702281A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
AU77022/81A 1980-11-03 1981-11-02 1-carboxy-azaalkanoylindoline-2-carboxylic acids Abandoned AU7702281A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20376980A 1980-11-03 1980-11-03
US203769 1980-11-03
US23991881A 1981-03-03 1981-03-03
US239918 1981-03-03

Publications (1)

Publication Number Publication Date
AU7702281A true AU7702281A (en) 1982-05-13

Family

ID=26898886

Family Applications (1)

Application Number Title Priority Date Filing Date
AU77022/81A Abandoned AU7702281A (en) 1980-11-03 1981-11-02 1-carboxy-azaalkanoylindoline-2-carboxylic acids

Country Status (13)

Country Link
EP (1) EP0051301A1 (enrdf_load_stackoverflow)
AU (1) AU7702281A (enrdf_load_stackoverflow)
CA (1) CA1172258A (enrdf_load_stackoverflow)
DD (1) DD201888A5 (enrdf_load_stackoverflow)
DK (1) DK483681A (enrdf_load_stackoverflow)
ES (3) ES506784A0 (enrdf_load_stackoverflow)
FI (1) FI813422A7 (enrdf_load_stackoverflow)
GB (1) GB2086390B (enrdf_load_stackoverflow)
GR (1) GR74689B (enrdf_load_stackoverflow)
HU (1) HU185324B (enrdf_load_stackoverflow)
IL (1) IL64185A0 (enrdf_load_stackoverflow)
NO (1) NO813694L (enrdf_load_stackoverflow)
PT (1) PT73916B (enrdf_load_stackoverflow)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN156096B (enrdf_load_stackoverflow) * 1981-03-19 1985-05-11 Usv Pharma Corp
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
ATE25244T1 (de) * 1981-12-29 1987-02-15 Hoechst Ag Neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung.
NZ202903A (en) * 1981-12-29 1988-01-08 Hoechst Ag 1-- pe pyrrol-2-yl-carboxylic acid derivatives and pharmaceutical compositions
DE3210496A1 (de) * 1982-03-23 1983-10-06 Hoechst Ag Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
US4520205A (en) * 1982-06-28 1985-05-28 American Home Products Corporation Chemical resolution of (+)-2,3-dihydroindole-2-carboxylic acid
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
FR2546886B2 (fr) * 1983-06-06 1986-05-16 Adir Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant
DE3324263A1 (de) * 1983-07-06 1985-01-17 Hoechst Ag, 6230 Frankfurt Derivate der 2-azabicyclo(3.1.0)hexan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(3.1.0)hexan-derivate als zwischenprodukte und verfahren zu deren herstellung
DE3333454A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
TW197945B (enrdf_load_stackoverflow) * 1990-11-27 1993-01-11 Hoechst Ag
US5504080A (en) * 1992-10-28 1996-04-02 Bristol-Myers Squibb Co. Benzo-fused lactams
WO1995001353A1 (en) * 1993-06-30 1995-01-12 Ciba-Geigy Ag Antihypertensive tricyclic azepine derivatives useful as inhibitors of enkephalinase and ace

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4303583A (en) * 1979-08-13 1981-12-01 American Home Products Corporation 1H,5H-[1,4]Thiazepino[4,3-a]indole-1,5-diones
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids

Also Published As

Publication number Publication date
HU185324B (en) 1985-01-28
ES8303329A1 (es) 1983-02-01
FI813422L (fi) 1982-05-04
IL64185A0 (en) 1982-02-28
NO813694L (no) 1982-05-04
ES8401026A1 (es) 1983-12-01
CA1172258A (en) 1984-08-07
ES8401025A1 (es) 1983-12-01
GR74689B (enrdf_load_stackoverflow) 1984-07-03
PT73916A (en) 1981-12-01
ES516556A0 (es) 1983-12-01
ES516555A0 (es) 1983-12-01
ES506784A0 (es) 1983-02-01
PT73916B (en) 1983-11-30
DK483681A (da) 1982-05-04
FI813422A7 (fi) 1982-05-04
GB2086390B (en) 1984-06-06
DD201888A5 (de) 1983-08-17
EP0051301A1 (de) 1982-05-12
GB2086390A (en) 1982-05-12

Similar Documents

Publication Publication Date Title
AU543861B2 (en) Oltahydro-1h-indole-2-carboxylic acids
AU540242B2 (en) 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthy-ridine- 3-carboxylic acids
AU544099B2 (en) Triazolylpentenols
AU537992B2 (en) Polusilanes
AU542600B2 (en) Platinum-diamines
AU545667B2 (en) Diamino-pyridines
AU7702281A (en) 1-carboxy-azaalkanoylindoline-2-carboxylic acids
AU539188B2 (en) Skin-packaging
AU538782B2 (en) Triazoloquinoxalin-4-ones
AU536754B2 (en) Imidodisulfamides
AU3206284A (en) 2-guanidno-4-heteroarylthiazoles
AU546022B2 (en) Combi-equipment
AU558451B2 (en) Amido-amino acids
AU545397B2 (en) Cloches
AU527275B2 (en) Auto-diaphragm hemodialyser
AU537824B2 (en) Oxygensensor
AU541912B2 (en) 2-nitroimidazoles
AU540787B2 (en) 4-indenyl-alkyl-piperidenes
AU538455B2 (en) N-glycosidal aminobenzoic acids
AU558708B2 (en) 6-bromo-3-chloromethyl-3-methyl-penam-2-carboxylic acids
AU543520B2 (en) Kijanimicin
AU534814B2 (en) Showstand
AU537073B2 (en) Haloacetanilide
AU538427B2 (en) Dichlorobenzoyl-3-phenylpyrazolines
AU548141B2 (en) 1-phenyl-2-triazolyl-pent-gen-3-ols