AU766748B2 - The therapeutic use of d-threo-methylphenidate for the treatment of attention-deficit hyperactivity disorder - Google Patents

The therapeutic use of d-threo-methylphenidate for the treatment of attention-deficit hyperactivity disorder Download PDF

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Publication number
AU766748B2
AU766748B2 AU55432/00A AU5543200A AU766748B2 AU 766748 B2 AU766748 B2 AU 766748B2 AU 55432/00 A AU55432/00 A AU 55432/00A AU 5543200 A AU5543200 A AU 5543200A AU 766748 B2 AU766748 B2 AU 766748B2
Authority
AU
Australia
Prior art keywords
mph
treatment
dose
saline
methylphenidate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU55432/00A
Other languages
English (en)
Other versions
AU5543200A (en
Inventor
Elizabeth Janina Davidson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celltech Pharma Europe Ltd
Original Assignee
Medeva Europe Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medeva Europe Ltd filed Critical Medeva Europe Ltd
Publication of AU5543200A publication Critical patent/AU5543200A/en
Application granted granted Critical
Publication of AU766748B2 publication Critical patent/AU766748B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AU55432/00A 1999-06-09 2000-06-08 The therapeutic use of d-threo-methylphenidate for the treatment of attention-deficit hyperactivity disorder Ceased AU766748B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9913458.7A GB9913458D0 (en) 1999-06-09 1999-06-09 The therapeutic use of d-threo-methylphenidate
GB9913458 1999-06-09
PCT/GB2000/002234 WO2000074680A1 (en) 1999-06-09 2000-06-08 The therapeutic use of d-threo-methylphenidate for the treatment of attention-deficit hyperactivity disorder

Publications (2)

Publication Number Publication Date
AU5543200A AU5543200A (en) 2000-12-28
AU766748B2 true AU766748B2 (en) 2003-10-23

Family

ID=10855048

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55432/00A Ceased AU766748B2 (en) 1999-06-09 2000-06-08 The therapeutic use of d-threo-methylphenidate for the treatment of attention-deficit hyperactivity disorder

Country Status (9)

Country Link
EP (1) EP1185268B1 (enExample)
JP (1) JP2003501387A (enExample)
AT (1) ATE302006T1 (enExample)
AU (1) AU766748B2 (enExample)
CA (1) CA2376215A1 (enExample)
DE (1) DE60022033T2 (enExample)
ES (1) ES2243273T3 (enExample)
GB (1) GB9913458D0 (enExample)
WO (1) WO2000074680A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US6486177B2 (en) 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US6962997B1 (en) 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
NZ556456A (en) 2005-01-20 2010-12-24 Inst Molecular Medicine Inc Methylphenidate derivatives and uses of them
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
JP6983161B2 (ja) 2015-09-15 2021-12-17 プラクシス・バイオリサーチ・エルエルシー フェンカンファミンのプロドラッグ

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997003673A1 (en) * 1995-07-14 1997-02-06 Medeva Europe Limited Sustained-release formulation of d-threo-methylphenidate
WO1999016439A1 (en) * 1997-09-29 1999-04-08 Celgene Corporation CHRONIC, BOLUS ADMINISTRATION OF D-threo METHYLPHENIDATE
US5908850A (en) * 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837284A (en) * 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
MX9805870A (enExample) * 1996-01-22 1999-01-31
US6210705B1 (en) * 1997-12-15 2001-04-03 Noven Pharmaceuticals, Nc. Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate
US6025502A (en) * 1999-03-19 2000-02-15 The Trustees Of The University Of Pennsylvania Enantopselective synthesis of methyl phenidate

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997003673A1 (en) * 1995-07-14 1997-02-06 Medeva Europe Limited Sustained-release formulation of d-threo-methylphenidate
US5908850A (en) * 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
WO1999016439A1 (en) * 1997-09-29 1999-04-08 Celgene Corporation CHRONIC, BOLUS ADMINISTRATION OF D-threo METHYLPHENIDATE

Also Published As

Publication number Publication date
ATE302006T1 (de) 2005-09-15
WO2000074680A1 (en) 2000-12-14
EP1185268A1 (en) 2002-03-13
GB9913458D0 (en) 1999-08-11
AU5543200A (en) 2000-12-28
DE60022033T2 (de) 2006-03-30
CA2376215A1 (en) 2000-12-14
JP2003501387A (ja) 2003-01-14
DE60022033D1 (de) 2005-09-22
ES2243273T3 (es) 2005-12-01
EP1185268B1 (en) 2005-08-17

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