AU763975B2 - Microparticles with adsorbent surfaces, methods of making same, and uses thereof - Google Patents
Microparticles with adsorbent surfaces, methods of making same, and uses thereof Download PDFInfo
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- AU763975B2 AU763975B2 AU52452/99A AU5245299A AU763975B2 AU 763975 B2 AU763975 B2 AU 763975B2 AU 52452/99 A AU52452/99 A AU 52452/99A AU 5245299 A AU5245299 A AU 5245299A AU 763975 B2 AU763975 B2 AU 763975B2
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- microparticle
- antigen
- detergent
- microparticles
- polypeptides
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- 238000012546 transfer Methods 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 239000003656 tris buffered saline Substances 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 244000052613 viral pathogen Species 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 238000002424 x-ray crystallography Methods 0.000 description 1
- BPKIMPVREBSLAJ-QTBYCLKRSA-N ziconotide Chemical compound C([C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]2C(=O)N[C@@H]3C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CSSC2)C(N)=O)=O)CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC3)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(N1)=O)CCSC)[C@@H](C)O)C1=CC=C(O)C=C1 BPKIMPVREBSLAJ-QTBYCLKRSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- AIDS & HIV (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Steroid Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003259663A AU2003259663B2 (en) | 1998-07-29 | 2003-11-05 | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12453398A | 1998-07-29 | 1998-07-29 | |
| US09/124533 | 1998-07-29 | ||
| US28585599A | 1999-04-02 | 1999-04-02 | |
| US09/285855 | 1999-04-02 | ||
| PCT/US1999/017308 WO2000006123A1 (en) | 1998-07-29 | 1999-07-29 | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003259663A Division AU2003259663B2 (en) | 1998-07-29 | 2003-11-05 | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU5245299A AU5245299A (en) | 2000-02-21 |
| AU763975B2 true AU763975B2 (en) | 2003-08-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU52452/99A Ceased AU763975B2 (en) | 1998-07-29 | 1999-07-29 | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1100468B1 (enExample) |
| JP (2) | JP4601168B2 (enExample) |
| AT (1) | ATE321535T1 (enExample) |
| AU (1) | AU763975B2 (enExample) |
| CA (1) | CA2338646C (enExample) |
| CY (1) | CY1107326T1 (enExample) |
| DE (1) | DE69930642T2 (enExample) |
| DK (1) | DK1100468T3 (enExample) |
| ES (1) | ES2260923T3 (enExample) |
| NZ (1) | NZ509853A (enExample) |
| PT (1) | PT1100468E (enExample) |
| WO (1) | WO2000006123A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1156781B1 (en) | 1999-02-26 | 2005-06-08 | Chiron Corporation | Microemulsions with adsorbed macromolecules and microparticles |
| US7713739B1 (en) | 2000-11-17 | 2010-05-11 | Novartis Vaccines And Diagnostics, Inc. | Microparticle-based transfection and activation of dendritic cells |
| AU2001281921A1 (en) * | 2000-06-29 | 2002-01-08 | Bernina Biosystems Gmbh | Bdellosomes |
| MXPA03002643A (es) | 2000-09-28 | 2003-06-19 | Chiron Corp | Composiciones de microparticulas y metodos para producirlas. |
| EP1438323A4 (en) * | 2001-10-03 | 2007-08-01 | Novartis Vaccines & Diagnostic | ADJUVOUS MENINGOCOCCUS COMPOSITIONS |
| US7838015B2 (en) * | 2001-10-03 | 2010-11-23 | Novartis Vaccines And Diagnostics, Inc. | Adjuvanted meningococcus compositions |
| AR045702A1 (es) * | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
| EP2572707A3 (en) | 2002-02-20 | 2013-11-06 | Novartis Vaccines and Diagnostics, Inc. | Microparticles with adsorbed polypeptide-containing molecules |
| CA2501476A1 (en) * | 2002-10-07 | 2004-04-22 | Chiron Corporation | Hiv vaccine formulations |
| EP2263687B1 (en) | 2002-12-27 | 2015-03-25 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic compositions containing phospholipid |
| US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
| JP5557415B2 (ja) | 2003-06-02 | 2014-07-23 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物 |
| FR2859909B1 (fr) | 2003-09-22 | 2007-09-07 | Biomerieux Sa | Procede de preparation de microparticules bioresorbables, microparticules obtenues et utilisation |
| US7899527B2 (en) * | 2004-05-13 | 2011-03-01 | Palo Alto Investors | Treatment of conditions through modulation of the autonomic nervous system during at least one predetermined menstrual cycle phase |
| CN101072585A (zh) | 2004-11-01 | 2007-11-14 | 诺华疫苗和诊断公司 | 产生免疫应答的组合方法 |
| EP1812056B1 (en) | 2004-11-15 | 2013-08-07 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic compositions containing anthrax antigen, biodegradable polymer microparticles, and polynucleotide-containing immunological adjuvant |
| CA2631714C (en) | 2005-12-02 | 2014-09-16 | Novartis Ag | Nanoparticles for use in immunogenic compositions |
| US8431160B2 (en) | 2006-02-24 | 2013-04-30 | Novartis Ag | Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions |
| EP3067048B1 (en) | 2007-12-07 | 2018-02-14 | GlaxoSmithKline Biologicals SA | Compositions for inducing immune responses |
| EP2282771B1 (en) | 2008-04-28 | 2014-06-25 | Novartis AG | Method for producing nanoparticles |
| BRPI1012036A2 (pt) | 2009-05-27 | 2017-10-10 | Selecta Biosciences Inc | nanocarreadores que possuem componentes com diferentes taxas de liberação |
| JP5867952B2 (ja) | 2009-06-10 | 2016-02-24 | ノバルティス アーゲー | ベンゾナフチリジン含有ワクチン |
| EP2525815B1 (en) * | 2010-01-24 | 2015-02-25 | Novartis AG | Irradiated biodegradable polymer microparticles |
| CA2798739A1 (en) | 2010-05-26 | 2011-12-01 | Selecta Biosciences, Inc. | Nanocarrier compositions with uncoupled adjuvant |
| KR20130121699A (ko) | 2010-05-28 | 2013-11-06 | 테트리스 온라인, 인코포레이티드 | 상호작용 혼성 비동기 컴퓨터 게임 기반구조 |
| US9192661B2 (en) | 2010-07-06 | 2015-11-24 | Novartis Ag | Delivery of self-replicating RNA using biodegradable polymer particles |
| EA201390660A1 (ru) | 2010-11-05 | 2013-11-29 | Селекта Байосайенсиз, Инк. | Модифицированные никотиновые соединения и связанные способы |
| MX350258B (es) | 2011-07-06 | 2017-08-31 | Novartis Ag | Emulsiones cationicas de aceite en agua. |
| JP6059220B2 (ja) | 2011-07-06 | 2017-01-18 | ノバルティス アーゲー | 核酸を含む水中油型エマルジョン |
| KR20140050698A (ko) | 2011-07-29 | 2014-04-29 | 셀렉타 바이오사이언시즈, 인크. | 체액성 및 세포독성 t 림프구(ctl) 면역 반응을 발생시키는 합성 나노운반체 |
| EP2968510B1 (en) | 2013-03-14 | 2019-10-09 | President and Fellows of Harvard College | Nanoparticle-based compositions |
| CA3246538A1 (en) | 2022-03-30 | 2023-10-05 | Evonik Operations Gmbh | Formulations composed of cationic lipids and poly(lactic-co-glycolic acid) for the administration of polynucleotides into cells |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996020698A2 (en) * | 1995-01-05 | 1996-07-11 | The Board Of Regents Acting For And On Behalf Of The University Of Michigan | Surface-modified nanoparticles and method of making and using same |
| WO1997002810A2 (en) * | 1995-07-13 | 1997-01-30 | Danbiosyst Uk Limited | Polymeric lamellar substrate particles for drug delivery |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5759583A (en) * | 1995-08-30 | 1998-06-02 | Syntex (U.S.A.) Inc. | Sustained release poly (lactic/glycolic) matrices |
| ATE235890T1 (de) * | 1997-01-30 | 2003-04-15 | Chiron Corp | Verwendung von mikropartikeln mit adsorbiertem antigen zur stimulierung der immunabwehr |
-
1999
- 1999-07-29 DE DE69930642T patent/DE69930642T2/de not_active Expired - Lifetime
- 1999-07-29 JP JP2000561979A patent/JP4601168B2/ja not_active Expired - Fee Related
- 1999-07-29 ES ES99937664T patent/ES2260923T3/es not_active Expired - Lifetime
- 1999-07-29 CA CA002338646A patent/CA2338646C/en not_active Expired - Fee Related
- 1999-07-29 EP EP99937664A patent/EP1100468B1/en not_active Expired - Lifetime
- 1999-07-29 WO PCT/US1999/017308 patent/WO2000006123A1/en not_active Ceased
- 1999-07-29 PT PT99937664T patent/PT1100468E/pt unknown
- 1999-07-29 DK DK99937664T patent/DK1100468T3/da active
- 1999-07-29 AT AT99937664T patent/ATE321535T1/de active
- 1999-07-29 NZ NZ509853A patent/NZ509853A/en not_active IP Right Cessation
- 1999-07-29 AU AU52452/99A patent/AU763975B2/en not_active Ceased
-
2006
- 2006-06-05 CY CY20061100736T patent/CY1107326T1/el unknown
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2010
- 2010-03-15 JP JP2010058491A patent/JP2010168392A/ja not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996020698A2 (en) * | 1995-01-05 | 1996-07-11 | The Board Of Regents Acting For And On Behalf Of The University Of Michigan | Surface-modified nanoparticles and method of making and using same |
| WO1997002810A2 (en) * | 1995-07-13 | 1997-01-30 | Danbiosyst Uk Limited | Polymeric lamellar substrate particles for drug delivery |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2338646C (en) | 2008-10-07 |
| JP4601168B2 (ja) | 2010-12-22 |
| CY1107326T1 (el) | 2012-11-21 |
| ATE321535T1 (de) | 2006-04-15 |
| ES2260923T3 (es) | 2006-11-01 |
| EP1100468A1 (en) | 2001-05-23 |
| AU5245299A (en) | 2000-02-21 |
| DK1100468T3 (da) | 2006-07-31 |
| JP2002521425A (ja) | 2002-07-16 |
| NZ509853A (en) | 2003-08-29 |
| WO2000006123A1 (en) | 2000-02-10 |
| DE69930642T2 (de) | 2006-12-28 |
| HK1035862A1 (en) | 2001-12-14 |
| EP1100468B1 (en) | 2006-03-29 |
| CA2338646A1 (en) | 2000-02-10 |
| PT1100468E (pt) | 2006-07-31 |
| DE69930642D1 (de) | 2006-05-18 |
| JP2010168392A (ja) | 2010-08-05 |
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