AU7570996A - Quinoline derivatives as type iv phosphodiesterase inhibitors - Google Patents

Quinoline derivatives as type iv phosphodiesterase inhibitors

Info

Publication number
AU7570996A
AU7570996A AU75709/96A AU7570996A AU7570996A AU 7570996 A AU7570996 A AU 7570996A AU 75709/96 A AU75709/96 A AU 75709/96A AU 7570996 A AU7570996 A AU 7570996A AU 7570996 A AU7570996 A AU 7570996A
Authority
AU
Australia
Prior art keywords
type
phosphodiesterase inhibitors
quinoline derivatives
quinoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU75709/96A
Other languages
English (en)
Inventor
Rainer Luond
Esteban Pombo Villar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis Erfindungen Verwaltungs GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Erfindungen Verwaltungs GmbH filed Critical Novartis Erfindungen Verwaltungs GmbH
Publication of AU7570996A publication Critical patent/AU7570996A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU75709/96A 1995-11-14 1996-11-13 Quinoline derivatives as type iv phosphodiesterase inhibitors Abandoned AU7570996A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9523267 1995-11-14
GBGB9523267.4A GB9523267D0 (en) 1995-11-14 1995-11-14 Organic compounds
PCT/EP1996/004978 WO1997018208A1 (fr) 1995-11-14 1996-11-13 Derives quinolines en tant qu'inhibiteurs des phosphodiesterases de type iv

Publications (1)

Publication Number Publication Date
AU7570996A true AU7570996A (en) 1997-06-05

Family

ID=10783856

Family Applications (1)

Application Number Title Priority Date Filing Date
AU75709/96A Abandoned AU7570996A (en) 1995-11-14 1996-11-13 Quinoline derivatives as type iv phosphodiesterase inhibitors

Country Status (17)

Country Link
EP (1) EP0873338A1 (fr)
JP (1) JPH11515000A (fr)
KR (1) KR19990067574A (fr)
CN (1) CN1202170A (fr)
AU (1) AU7570996A (fr)
BR (1) BR9611504A (fr)
CA (1) CA2235126A1 (fr)
CO (1) CO4770973A1 (fr)
CZ (1) CZ149498A3 (fr)
GB (1) GB9523267D0 (fr)
HU (1) HUP9903492A3 (fr)
MX (1) MX9803839A (fr)
PE (1) PE17598A1 (fr)
PL (1) PL326636A1 (fr)
SK (1) SK63998A3 (fr)
TR (1) TR199800851T2 (fr)
WO (1) WO1997018208A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100701904B1 (ko) 1999-08-21 2007-04-02 알타나 파마 아게 Ｐｄｅ 억제제 및 베타 2 아드레날린수용체 작동제의상승적 조합
CN1520313A (zh) 2001-05-23 2004-08-11 ������ҩ��ʽ���� 一种加速骨折愈合的组合物
CA2447618A1 (fr) 2001-05-23 2002-11-28 Tanabe Seiyaku Co., Ltd. Composition pour le traitement regeneratif de la maladie du cartilage
TW200536851A (en) * 2004-01-23 2005-11-16 Amgen Inc Compounds and methods of use
JP2006347936A (ja) * 2005-06-15 2006-12-28 Bayer Cropscience Ag 殺虫性ベンズアニリド類
AR081377A1 (es) 2010-05-10 2012-08-29 Gilead Sciences Inc Compuestos de pirazolopiridina bifuncionales
EP2569285A1 (fr) 2010-05-10 2013-03-20 Gilead Sciences, Inc. Dérivés quinoliniques bifonctionnels
AR093017A1 (es) 2012-10-16 2015-05-13 Janssen Pharmaceutica Nv MODULARES DE RORgT DE QUINOLINILO UNIDOS POR METILENO
JP6250686B2 (ja) 2012-10-16 2017-12-20 ヤンセン ファーマシューティカ エヌ．ベー． Ｒｏｒγｔのヘテロアリール結合させたキノリニルモジュレータ
JP6251277B2 (ja) 2012-10-16 2017-12-20 ヤンセン ファーマシューティカ エヌ．ベー． ＲＯＲ−ガンマ−ｔのフェニル結合キノリニルモジュレーター
US10555941B2 (en) 2013-10-15 2020-02-11 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of RORγt
ES2770727T3 (es) 2013-10-15 2020-07-02 Janssen Pharmaceutica Nv Moduladores de quinilonila enlazados a alquilo de ROR(gamma)t
US9328095B2 (en) 2013-10-15 2016-05-03 Janssen Pharmaceutica Nv Heteroaryl linked quinolinyl modulators of RORgammat
US9284308B2 (en) 2013-10-15 2016-03-15 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of RORγt
US9221804B2 (en) 2013-10-15 2015-12-29 Janssen Pharmaceutica Nv Secondary alcohol quinolinyl modulators of RORγt
US9403816B2 (en) 2013-10-15 2016-08-02 Janssen Pharmaceutica Nv Phenyl linked quinolinyl modulators of RORγt
US9624225B2 (en) 2013-10-15 2017-04-18 Janssen Pharmaceutica Nv Quinolinyl modulators of RORγt
EP3813532B1 (fr) * 2018-06-24 2024-02-28 Adama Agan Ltd. Procédé de préparation de quinmérac

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9027055D0 (en) * 1990-12-13 1991-02-06 Sandoz Ltd Organic compounds
US5455252A (en) * 1993-03-31 1995-10-03 Syntex (U.S.A.) Inc. Optionally substituted 6,8-quinolines

Also Published As

Publication number Publication date
MX9803839A (es) 1998-09-30
KR19990067574A (ko) 1999-08-25
CZ149498A3 (cs) 1998-08-12
CA2235126A1 (fr) 1997-05-22
GB9523267D0 (en) 1996-01-17
WO1997018208A1 (fr) 1997-05-22
CO4770973A1 (es) 1999-04-30
SK63998A3 (en) 1998-10-07
HUP9903492A3 (en) 2000-08-28
PL326636A1 (en) 1998-10-12
EP0873338A1 (fr) 1998-10-28
CN1202170A (zh) 1998-12-16
PE17598A1 (es) 1998-04-06
TR199800851T2 (xx) 1998-08-21
JPH11515000A (ja) 1999-12-21
BR9611504A (pt) 1999-03-02
HUP9903492A2 (en) 2000-07-28

Similar Documents

Publication Publication Date Title
AU6419296A (en) Cyclic gmp-specific phosphodiesterase inhibitors
AU1301697A (en) Tyrosin-derivate as alpha-v-integrin inhibitors
AU7692696A (en) Heteroaryl derivatives
PL326967A1 (en) Quinoline derivatives
AU4791797A (en) 6-phenylpyridyl-2-amine derivatives useful as nos inhibitors
AU2747395A (en) Substituted oxime derivatives useful as pde iv inhibitors
AU2717899A (en) Quinoline derivatives as antibacterials
AU7631496A (en) Substituted 2-anilinopyrimidines useful as protein kinase inhibitors
AU5343396A (en) Quinazoline derivatives
AU5040696A (en) Quinazoline derivatives
AU5343296A (en) Quinazoline derivatives
AU5343096A (en) Quinazoline derivatives
AU7131196A (en) Pyrimidine derivatives as 5ht2c-receptor antagonists
AU7570996A (en) Quinoline derivatives as type iv phosphodiesterase inhibitors
AU2274299A (en) Benzazine derivatives phosphodiesterase 4 inhibitors
AU6318196A (en) Novel benzimidazole derivatives having cgmp-phosphodisterase inhibiting activity
AU7295196A (en) 4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity
AU4779297A (en) Pde iv inhibiting 2-cyanoiminoimidazole derivatives
AU7295096A (en) 4-phenyl-4-oxo-2-butenoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity
AU6384296A (en) Acyclovir derivatives for topical use
AU1605699A (en) Substituted 3-amino-2-hydroxyphenylacetamide derivatives as enzyme inhibitors (ii)
AU3578695A (en) Acridone derivative
ZA969812B (en) Novel quinoline derivatives.
AU3299193A (en) Biphenyl-substituted quinoline derivatives
AU4501199A (en) 8-phenylxanthine derivatives and their use as phosphodiesterase inhibitors

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted