AU742970C - Method of suppressing beta-amyloid-related changes in Alzheimer's disease - Google Patents
Method of suppressing beta-amyloid-related changes in Alzheimer's diseaseInfo
- Publication number
- AU742970C AU742970C AU17099/99A AU1709999A AU742970C AU 742970 C AU742970 C AU 742970C AU 17099/99 A AU17099/99 A AU 17099/99A AU 1709999 A AU1709999 A AU 1709999A AU 742970 C AU742970 C AU 742970C
- Authority
- AU
- Australia
- Prior art keywords
- disease
- amyloid
- mammal
- administration
- alzheimer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2026—IL-4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Marine Sciences & Fisheries (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
- Engine Equipment That Uses Special Cycles (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU27727/02A AU781126B2 (en) | 1997-12-03 | 2002-03-28 | Method of suppressing beta-amyloid-related changes in Alzheimer's disease |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6721997P | 1997-12-03 | 1997-12-03 | |
US60/067219 | 1997-12-03 | ||
US7969798P | 1998-03-27 | 1998-03-27 | |
US60/079697 | 1998-03-27 | ||
PCT/US1998/025694 WO1999027949A1 (en) | 1997-12-03 | 1998-12-03 | METHOD OF SUPPRESSING β-AMYLOID-RELATED CHANGES IN ALZHEIMER'S DISEASE |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU27727/02A Division AU781126B2 (en) | 1997-12-03 | 2002-03-28 | Method of suppressing beta-amyloid-related changes in Alzheimer's disease |
Publications (3)
Publication Number | Publication Date |
---|---|
AU1709999A AU1709999A (en) | 1999-06-16 |
AU742970B2 AU742970B2 (en) | 2002-01-17 |
AU742970C true AU742970C (en) | 2003-03-20 |
Family
ID=26747618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU17099/99A Expired AU742970C (en) | 1997-12-03 | 1998-12-03 | Method of suppressing beta-amyloid-related changes in Alzheimer's disease |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1033998B1 (zh) |
JP (2) | JP2002511385A (zh) |
AT (1) | ATE306931T1 (zh) |
AU (1) | AU742970C (zh) |
CA (1) | CA2312475C (zh) |
DE (2) | DE1033998T1 (zh) |
ES (1) | ES2253839T3 (zh) |
WO (1) | WO1999027949A1 (zh) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0866805A1 (en) | 1995-12-12 | 1998-09-30 | Karolinska Innovations AB | PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b) |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US6750324B1 (en) | 1997-12-02 | 2004-06-15 | Neuralab Limited | Humanized and chimeric N-terminal amyloid beta-antibodies |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
US6787523B1 (en) | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US6905686B1 (en) | 1997-12-02 | 2005-06-14 | Neuralab Limited | Active immunization for treatment of alzheimer's disease |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
EP1033998B1 (en) * | 1997-12-03 | 2005-10-19 | Neuralab, Ltd. | Suppressing beta-amyloid-related changes in alzheimer's disease |
US20030147882A1 (en) | 1998-05-21 | 2003-08-07 | Alan Solomon | Methods for amyloid removal using anti-amyloid antibodies |
US7060670B1 (en) | 1999-05-05 | 2006-06-13 | Neurochem (International) Limited | Stereoselective antifibrillogenic peptides and peptidomimetics thereof |
US6787637B1 (en) | 1999-05-28 | 2004-09-07 | Neuralab Limited | N-Terminal amyloid-β antibodies |
UA81216C2 (en) | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
CN1249085C (zh) * | 2000-05-22 | 2006-04-05 | 纽约大学 | 诱导对β淀粉状蛋白和淀粉状蛋白沉积物的免疫反应、与β淀粉状蛋白同源的免疫源性但非淀粉状蛋白源性合成肽 |
AU2001268005A1 (en) | 2000-07-07 | 2002-01-21 | Lars Lannfelt | Prevention and treatment of alzheimer's disease |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
US7320793B2 (en) | 2001-01-19 | 2008-01-22 | Cytos Biotechnology Ag | Molecular antigen array |
AU2002357007A1 (en) | 2001-11-21 | 2003-06-10 | New York University | SYNTHETIC IMMUNOGENIC BUT NON-DEPOSIT-FORMING POLYPEPTIDES AND PEPTIDES HOMOLOGOUS TO AMYLOID Beta, PRION PROTEIN, AMYLIN, Alpha-SYNUCLEIN, OR POLYGLUTAMINE REPEATS FOR INDUCTION OF AN IMMUNE RESPONSE THERETO |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
SI1524994T1 (sl) | 2002-07-19 | 2011-08-31 | Cytos Biotechnology Ag | Sestavki cepiv, ki vsebujejo amiloidne beta 1-6 antigenske mreĹľe |
AU2003303198A1 (en) | 2002-12-19 | 2004-07-14 | New York University | Method for treating amyloid disease |
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
TWI374893B (en) | 2003-05-30 | 2012-10-21 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
SE0401601D0 (sv) | 2004-06-21 | 2004-06-21 | Bioarctic Neuroscience Ab | Protofibril specific antibodies and uses thereof |
GB0424563D0 (en) | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
PE20061329A1 (es) | 2004-12-15 | 2006-12-08 | Neuralab Ltd | Anticuerpos ab humanizados para mejorar la cognicion |
GT200600031A (es) | 2005-01-28 | 2006-08-29 | Formulacion anticuerpo anti a beta | |
KR20180058863A (ko) | 2005-11-30 | 2018-06-01 | 애브비 인코포레이티드 | 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도 |
RU2442793C2 (ru) | 2005-11-30 | 2012-02-20 | Эбботт Лэборетриз | АНТИТЕЛА ПРОТИВ ГЛОБУЛОМЕРА Аβ, ИХ АНТИГЕНСВЯЗЫВАЮЩИЕ ЧАСТИ, СООТВЕТСТВУЮЩИЕ ГИБРИДОМЫ, НУКЛЕИНОВЫЕ КИСЛОТЫ, ВЕКТОРЫ, КЛЕТКИ-ХОЗЯЕВА, СПОСОБЫ ПОЛУЧЕНИЯ УКАЗАННЫХ АНТИТЕЛ, КОМПОЗИЦИИ, СОДЕРЖАЩИЕ УКАЗАННЫЕ АНТИТЕЛА, ПРИМЕНЕНИЯ УКАЗАННЫХ АНТИТЕЛ И СПОСОБЫ ИСПОЛЬЗОВАНИЯ УКАЗАННЫХ АНТИТЕЛ |
SI2004688T2 (sl) | 2006-03-23 | 2014-05-30 | Bioarctic Neuroscience Ab | Izboljšana protofibrilno selektivna protitelesa in njihova uporaba |
US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
SI2182983T1 (sl) | 2007-07-27 | 2014-09-30 | Janssen Alzheimer Immunotherapy | Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta |
JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
ES2684475T3 (es) | 2010-04-15 | 2018-10-03 | Abbvie Inc. | Proteínas que se unen a beta amiloide |
US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
WO2013012811A2 (en) | 2011-07-19 | 2013-01-24 | New York University | Immunotherapeutic modulation of amyloidogenic disease using non-fibrillogenic, non-amyloidogenic polymerized proteins and peptides |
WO2013013056A1 (en) | 2011-07-19 | 2013-01-24 | New York University | Method for treating amyloid disease |
JP2016503410A (ja) * | 2012-11-09 | 2016-02-04 | スリーイー セラピューティクス コーポレイション3E Therapeutics Corporation | X線造影剤組成物およびそれを使用して炎症関連症状を治療する方法 |
EP3166970B1 (en) | 2014-07-10 | 2021-03-10 | BioArctic AB | Improved a-beta protofibril binding antibodies |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5223482A (en) * | 1986-11-17 | 1993-06-29 | Scios Nova Inc. | Recombinant Alzheimer's protease inhibitory amyloid protein and method of use |
CA2081482C (en) * | 1990-04-27 | 2000-11-21 | Ellis L. Kline | Method and composition for treatment of central nervous system disease states associated with abnormal amyloid beta protein molecular organization |
WO1995031996A1 (en) * | 1994-05-25 | 1995-11-30 | Milkhaus Lab | Materials and methods for treatment of plaquing diseases |
WO1996039176A1 (en) * | 1995-06-05 | 1996-12-12 | Brigham & Women's Hospital | USE OF ORAL TOLERANCE TO SUPPRESS BOTH Th1 AND Th2 IMMUNE RESPONSES AND TO SUPPRESS ANTIBODY PRODUCTION |
WO1997018855A1 (en) * | 1995-11-21 | 1997-05-29 | Eduard Naumovich Lerner | Device for enhanced delivery of biologically active substances and compounds in an organism |
ZA97452B (en) * | 1996-01-25 | 1997-08-15 | Trinity College Dublin | Streptococcus equi vaccine. |
JPH09208485A (ja) * | 1996-01-31 | 1997-08-12 | Teijin Ltd | ペプチド・蛋白質性薬物の水難溶性組成物 |
EP1033998B1 (en) * | 1997-12-03 | 2005-10-19 | Neuralab, Ltd. | Suppressing beta-amyloid-related changes in alzheimer's disease |
-
1998
- 1998-12-03 EP EP98961894A patent/EP1033998B1/en not_active Expired - Lifetime
- 1998-12-03 JP JP2000522934A patent/JP2002511385A/ja active Pending
- 1998-12-03 DE DE1033998T patent/DE1033998T1/de active Pending
- 1998-12-03 DE DE69831971T patent/DE69831971T2/de not_active Expired - Lifetime
- 1998-12-03 AU AU17099/99A patent/AU742970C/en not_active Expired
- 1998-12-03 CA CA2312475A patent/CA2312475C/en not_active Expired - Lifetime
- 1998-12-03 WO PCT/US1998/025694 patent/WO1999027949A1/en active IP Right Grant
- 1998-12-03 ES ES98961894T patent/ES2253839T3/es not_active Expired - Lifetime
- 1998-12-03 AT AT98961894T patent/ATE306931T1/de not_active IP Right Cessation
-
2010
- 2010-04-02 JP JP2010086400A patent/JP2010215627A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2312475A1 (en) | 1999-06-10 |
JP2002511385A (ja) | 2002-04-16 |
EP1033998B1 (en) | 2005-10-19 |
WO1999027949A1 (en) | 1999-06-10 |
ATE306931T1 (de) | 2005-11-15 |
EP1033998A1 (en) | 2000-09-13 |
DE69831971T2 (de) | 2006-07-06 |
WO1999027949A9 (en) | 1999-09-10 |
ES2253839T3 (es) | 2006-06-01 |
JP2010215627A (ja) | 2010-09-30 |
CA2312475C (en) | 2010-08-03 |
DE69831971D1 (de) | 2006-03-02 |
DE1033998T1 (de) | 2001-05-23 |
AU742970B2 (en) | 2002-01-17 |
EP1033998A4 (en) | 2003-06-04 |
AU1709999A (en) | 1999-06-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU742970C (en) | Method of suppressing beta-amyloid-related changes in Alzheimer's disease | |
JP3712260B2 (ja) | 自己免疫疾患のバイスタンダー抑制 | |
JP2548056B2 (ja) | I型糖尿病に係る自己免疫疾患の抑制および予防用製剤 | |
JP4216342B2 (ja) | コポリマー1の摂取又は吸入を通じての多発性硬化症の治療 | |
US5720955A (en) | Method of treating rheumatoid arthritis with soluble collagen | |
WO1994007520A1 (en) | Method of treating rheumatoid arthritis with type ii collagen | |
WO1994007520A9 (en) | Method of treating rheumatoid arthritis with type ii collagen | |
JP2001511134A (ja) | メトトレキサートと組合せる耐性化を用いる自己免疫疾患の治療 | |
KR0159046B1 (ko) | 포유류의 자기면역 포도막망막염의 치료 또는 예방방법 | |
US20010007758A1 (en) | Treatment of multiple sclerosis using COP-1 and Th2-enhancing cytokines | |
JPH09511745A (ja) | 経口寛容および/またはタイプiインターフェロンを用いた自己免疫疾患の治療 | |
US6812205B2 (en) | Suppression of vascular disorders by mucosal administration of heat shock protein peptides | |
WO2007028133A2 (en) | Treatment and prevention of vascular dementia | |
AU781126B2 (en) | Method of suppressing beta-amyloid-related changes in Alzheimer's disease | |
CA2410563C (en) | Methods for preventing strokes by inducing tolerance to e-selectin | |
JP3845447B2 (ja) | タイプ▲ii▼コラーゲンによるリウマチ性関節炎治療方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FGA | Letters patent sealed or granted (standard patent) | ||
PC | Assignment registered |
Owner name: NEURALAB LIMITED Free format text: FORMER OWNER WAS: BRIGHAM AND WOMEN'S HOSPITAL |
|
DA2 | Applications for amendment section 104 |
Free format text: THE NATURE OF THE PROPOSED AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20020702 |
|
DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS AS WAS NOTIFIED IN THE OFFICIAL JOURNAL DATED 20020912 |
|
MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |