AU740238B2 - Method for polynucleotide sequencing - Google Patents
Method for polynucleotide sequencing Download PDFInfo
- Publication number
- AU740238B2 AU740238B2 AU38784/97A AU3878497A AU740238B2 AU 740238 B2 AU740238 B2 AU 740238B2 AU 38784/97 A AU38784/97 A AU 38784/97A AU 3878497 A AU3878497 A AU 3878497A AU 740238 B2 AU740238 B2 AU 740238B2
- Authority
- AU
- Australia
- Prior art keywords
- primer
- template
- polynucleotide
- analog
- polymerase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000000034 method Methods 0.000 title claims description 90
- 108091033319 polynucleotide Proteins 0.000 title claims description 66
- 102000040430 polynucleotide Human genes 0.000 title claims description 66
- 239000002157 polynucleotide Substances 0.000 title claims description 66
- 238000012163 sequencing technique Methods 0.000 title claims description 33
- 125000003729 nucleotide group Chemical group 0.000 claims description 66
- 239000002773 nucleotide Substances 0.000 claims description 64
- -1 nucleoside triphosphate Chemical class 0.000 claims description 56
- 239000002777 nucleoside Substances 0.000 claims description 53
- 239000001226 triphosphate Substances 0.000 claims description 47
- 235000011178 triphosphate Nutrition 0.000 claims description 47
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- 101001093748 Homo sapiens Phosphatidylinositol N-acetylglucosaminyltransferase subunit P Proteins 0.000 description 4
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- 125000002264 triphosphate group Chemical class [H]OP(=O)(O[H])OP(=O)(O[H])OP(=O)(O[H])O* 0.000 description 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 2
- XPDXVDYUQZHFPV-UHFFFAOYSA-N Dansyl Chloride Chemical compound C1=CC=C2C(N(C)C)=CC=CC2=C1S(Cl)(=O)=O XPDXVDYUQZHFPV-UHFFFAOYSA-N 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
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- 230000005257 nucleotidylation Effects 0.000 description 2
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- NPEIGRBGMUJNFE-UHFFFAOYSA-N 1-aminohexan-1-ol Chemical compound CCCCCC(N)O NPEIGRBGMUJNFE-UHFFFAOYSA-N 0.000 description 1
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- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
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- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66521096A | 1996-06-14 | 1996-06-14 | |
| US08/665210 | 1996-06-14 | ||
| PCT/US1997/009664 WO1997047761A1 (en) | 1996-06-14 | 1997-06-13 | Method for polynucleotide sequencing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU3878497A AU3878497A (en) | 1998-01-07 |
| AU740238B2 true AU740238B2 (en) | 2001-11-01 |
Family
ID=24669185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU38784/97A Ceased AU740238B2 (en) | 1996-06-14 | 1997-06-13 | Method for polynucleotide sequencing |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5908755A (enExample) |
| EP (1) | EP0912752A1 (enExample) |
| JP (1) | JP2000512498A (enExample) |
| AU (1) | AU740238B2 (enExample) |
| CA (1) | CA2258511A1 (enExample) |
| IL (1) | IL127560A0 (enExample) |
| WO (1) | WO1997047761A1 (enExample) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830655A (en) | 1995-05-22 | 1998-11-03 | Sri International | Oligonucleotide sizing using cleavable primers |
| US6391622B1 (en) * | 1997-04-04 | 2002-05-21 | Caliper Technologies Corp. | Closed-loop biochemical analyzers |
| US6235471B1 (en) * | 1997-04-04 | 2001-05-22 | Caliper Technologies Corp. | Closed-loop biochemical analyzers |
| US6780591B2 (en) | 1998-05-01 | 2004-08-24 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
| US7875440B2 (en) | 1998-05-01 | 2011-01-25 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
| GB9828785D0 (en) * | 1998-12-30 | 1999-02-17 | Amersham Pharm Biotech Ab | Sequencing systems |
| WO2000058507A1 (en) * | 1999-03-30 | 2000-10-05 | Solexa Ltd. | Polynucleotide sequencing |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| US7668658B2 (en) | 1999-10-13 | 2010-02-23 | Sequenom, Inc. | Methods for generating databases and databases for identifying polymorphic genetic markers |
| WO2001032930A1 (en) * | 1999-11-04 | 2001-05-10 | California Institute Of Technology | Methods and apparatuses for analyzing polynucleotide sequences |
| US6958214B2 (en) | 2000-07-10 | 2005-10-25 | Sequenom, Inc. | Polymorphic kinase anchor proteins and nucleic acids encoding the same |
| GB0021286D0 (en) * | 2000-08-30 | 2000-10-18 | Gemini Genomics Ab | Identification of drug metabolic capacity |
| US9708358B2 (en) | 2000-10-06 | 2017-07-18 | The Trustees Of Columbia University In The City Of New York | Massive parallel method for decoding DNA and RNA |
| WO2002029003A2 (en) | 2000-10-06 | 2002-04-11 | The Trustees Of Columbia University In The City Of New York | Massive parallel method for decoding dna and rna |
| US6720148B1 (en) * | 2001-02-22 | 2004-04-13 | Caliper Life Sciences, Inc. | Methods and systems for identifying nucleotides by primer extension |
| US7110885B2 (en) | 2001-03-08 | 2006-09-19 | Dnaprint Genomics, Inc. | Efficient methods and apparatus for high-throughput processing of gene sequence data |
| JP2004523243A (ja) * | 2001-03-12 | 2004-08-05 | カリフォルニア インスティチュート オブ テクノロジー | 非同期性塩基伸長によってポリヌクレオチド配列を分析するための方法および装置 |
| JP3871301B2 (ja) * | 2001-05-15 | 2007-01-24 | インターナショナル・ビジネス・マシーンズ・コーポレーション | データベース検索装置、及びプログラム |
| US20030224380A1 (en) * | 2001-10-25 | 2003-12-04 | The General Hospital Corporation | Genes and polymorphisms on chromosome 10 associated with Alzheimer's disease and other neurodegenerative diseases |
| AU2002364945A1 (en) * | 2001-10-25 | 2003-07-09 | Neurogenetics, Inc. | Genes and polymorphisms on chromosome 10 associated with alzheimer's disease and other neurodegenerative diseases |
| US20030170678A1 (en) * | 2001-10-25 | 2003-09-11 | Neurogenetics, Inc. | Genetic markers for Alzheimer's disease and methods using the same |
| CA2464682A1 (en) * | 2001-10-26 | 2003-05-01 | Sequenom, Inc. | Method and apparatus for high-throughput sample handling process line |
| WO2003093296A2 (en) | 2002-05-03 | 2003-11-13 | Sequenom, Inc. | Kinase anchor protein muteins, peptides thereof, and related methods |
| US20030220844A1 (en) * | 2002-05-24 | 2003-11-27 | Marnellos Georgios E. | Method and system for purchasing genetic data |
| EP2112229A3 (en) | 2002-11-25 | 2009-12-02 | Sequenom, Inc. | Methods for identifying risk of breast cancer and treatments thereof |
| AU2003302770B2 (en) | 2002-12-20 | 2007-07-12 | Caliper Life Sciences, Inc. | Single molecule amplification and detection of DNA |
| US20060147935A1 (en) * | 2003-02-12 | 2006-07-06 | Sten Linnarsson | Methods and means for nucleic acid sequencing |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| DE602005020421D1 (de) | 2004-02-19 | 2010-05-20 | Helicos Biosciences Corp | Verfahren zur analyse von polynukleotidsequenzen |
| US7635562B2 (en) | 2004-05-25 | 2009-12-22 | Helicos Biosciences Corporation | Methods and devices for nucleic acid sequence determination |
| US7476734B2 (en) | 2005-12-06 | 2009-01-13 | Helicos Biosciences Corporation | Nucleotide analogs |
| US20080199480A1 (en) * | 2004-07-22 | 2008-08-21 | Sequenom, Inc. | Methods for Identifying Risk of Type II Diabetes and Treatments Thereof |
| US7220549B2 (en) | 2004-12-30 | 2007-05-22 | Helicos Biosciences Corporation | Stabilizing a nucleic acid for nucleic acid sequencing |
| US7482120B2 (en) | 2005-01-28 | 2009-01-27 | Helicos Biosciences Corporation | Methods and compositions for improving fidelity in a nucleic acid synthesis reaction |
| US7666593B2 (en) | 2005-08-26 | 2010-02-23 | Helicos Biosciences Corporation | Single molecule sequencing of captured nucleic acids |
| US7397546B2 (en) | 2006-03-08 | 2008-07-08 | Helicos Biosciences Corporation | Systems and methods for reducing detected intensity non-uniformity in a laser beam |
| US20080309926A1 (en) * | 2006-03-08 | 2008-12-18 | Aaron Weber | Systems and methods for reducing detected intensity non uniformity in a laser beam |
| EP2029777B1 (en) | 2006-05-31 | 2017-03-08 | Sequenom, Inc. | Methods and compositions for the extraction of nucleic acid from a sample |
| WO2007140599A1 (en) | 2006-06-05 | 2007-12-13 | Cancer Care Ontario | Assessment of risk for colorectal cancer |
| GB2457402B (en) | 2006-12-01 | 2011-10-19 | Univ Columbia | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators |
| US7902345B2 (en) | 2006-12-05 | 2011-03-08 | Sequenom, Inc. | Detection and quantification of biomolecules using mass spectrometry |
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- 1997-06-13 AU AU38784/97A patent/AU740238B2/en not_active Ceased
- 1997-06-13 EP EP97936015A patent/EP0912752A1/en not_active Withdrawn
- 1997-06-13 JP JP10501677A patent/JP2000512498A/ja active Pending
- 1997-06-13 IL IL12756097A patent/IL127560A0/xx unknown
- 1997-06-13 CA CA002258511A patent/CA2258511A1/en not_active Abandoned
- 1997-06-13 WO PCT/US1997/009664 patent/WO1997047761A1/en not_active Ceased
- 1997-10-15 US US08/950,709 patent/US5908755A/en not_active Expired - Lifetime
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| WO1990013666A1 (en) * | 1989-05-11 | 1990-11-15 | Amersham International Plc | Sequencing method |
| US5403708A (en) * | 1992-07-06 | 1995-04-04 | Brennan; Thomas M. | Methods and compositions for determining the sequence of nucleic acids |
Also Published As
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|---|---|
| AU3878497A (en) | 1998-01-07 |
| EP0912752A1 (en) | 1999-05-06 |
| CA2258511A1 (en) | 1997-12-18 |
| JP2000512498A (ja) | 2000-09-26 |
| WO1997047761A1 (en) | 1997-12-18 |
| US5908755A (en) | 1999-06-01 |
| IL127560A0 (en) | 1999-10-28 |
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